Mehmet Ali Kobat

ORCID: 0000-0002-2217-2925
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About
Contact & Profiles
Research Areas
  • Phonocardiography and Auscultation Techniques
  • Atherosclerosis and Cardiovascular Diseases
  • Cardiac electrophysiology and arrhythmias
  • Atrial Fibrillation Management and Outcomes
  • ECG Monitoring and Analysis
  • COVID-19 diagnosis using AI
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Cardiovascular Disease and Adiposity
  • Cardiac Arrhythmias and Treatments
  • Coronary Interventions and Diagnostics
  • Apelin-related biomedical research
  • Cardiovascular, Neuropeptides, and Oxidative Stress Research
  • Adipose Tissue and Metabolism
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Acute Myocardial Infarction Research
  • Lipoproteins and Cardiovascular Health
  • Galectins and Cancer Biology
  • Cardiovascular Function and Risk Factors
  • Cardiac Valve Diseases and Treatments
  • Coronary Artery Anomalies
  • Dental Implant Techniques and Outcomes
  • Inflammatory Biomarkers in Disease Prognosis
  • Advanced Computing and Algorithms
  • Reproductive System and Pregnancy
  • Pregnancy and preeclampsia studies

Fırat University
2014-2025

Elazığ Eğitim ve Araştırma Hastanesi
2009-2015

GTx (United States)
2014

Summary The pathophysiology of cardiac syndrome X ( CSX ) is still unclear, but most patients with have endothelial dysfunction. It has been shown that adropin uniquely effects the regulation function. purpose study was to evaluate role in . Eighty‐six consecutive ‐diagnosed and 86 age‐sex matched healthy subjects were enrolled into study. Serum levels, nitrite/nitrate levels measured each subject. significantly lower than (1.7 ± 0.8 ng/ mL 3.4 1.8 , respectively; P < 0.001). BMI values...

10.1111/1755-5922.12025 article EN Cardiovascular Therapeutics 2013-01-29

Chronic inflammatory diseases are associated with an accelerated atherosclerotic process. Recent studies have discussed whether bowel (IBDs) can predict early atherosclerosis. We investigated this possibility.The study consisted of IBD cases (group 1, n = 40) and healthy persons 2, 40). The group was selected so as not to vascular disease or the presence established major cardiovascular risk factors.Group 1 showed a significant increase in carotid intima media thickness (cIMT; P .01)....

10.1177/0003319709333869 article EN Angiology 2009-04-26

Background/Objectives: Heart attacks are the leading cause of death in world. There two important classes heart attack: ST-segment Elevation Myocardial Infarction (STEMI) and Non-ST-segment (NSTEMI) patient groups. While STEMI group has a higher mortality rate short term, NSTEMI is considered more dangerous insidious long term. Blocked coronary arteries can be predicted from ECG signals patients but not patients. Therefore, angiography (CAG) inevitable for these However, elderly some with...

10.3390/diagnostics15030347 article EN cc-by Diagnostics 2025-02-02

COVID-19 and heart failure (HF) are common disorders although they share some similar symptoms, require different treatments. Accurate diagnosis of these is crucial for disease management, including patient isolation to curb infection spread COVID-19. In this work, we aim develop a computer-aided diagnostic system that can accurately differentiate three classes (normal, HF) using cough sounds. A novel handcrafted model was used classify vs. healthy (Case 1), HF 2) 3) automatically...

10.3390/diagnostics11111962 article EN cc-by Diagnostics 2021-10-22

The awareness, time in therapeutic range (TTR), and safety of warfarin therapy were investigated the adult Turkish population.This multicenter prospective study includes 4987 patients using involved regular international normalized ratio (INR) monitoring between January 1, 2014 December 31, 2014. TTR was calculated according to F.R. Roosendaal's algorithm. Awareness evaluated based on patients' knowledge warfarin's affect food-drug interactions.The mean 49.52±22.93%. with hypertension...

10.5152/anatoljcardiol.2015.6474 article EN cc-by-nc The Anatolian Journal of Cardiology 2015-11-19

Abstract COVID‐19, chronic obstructive pulmonary disease (COPD), heart failure (HF), and pneumonia can lead to acute respiratory deterioration. Prompt accurate diagnosis is crucial for effective clinical management. Chest X‐ray (CXR) chest computed tomography (CT) are commonly used confirming the diagnosis, but they be time‐consuming biased. To address this, we developed a computationally efficient deep feature engineering model called Hybrid‐Patch‐Alex automated COPD, HF diagnosis. We...

10.1002/ima.22914 article EN International Journal of Imaging Systems and Technology 2023-05-29

Index of cardio-electrophysiological balance (iCEB) has been described as a novel risk marker for predicting malignant ventricular arrhythmia. There remains limited evidence on the effects amiodarone and propafenone used sinus rhythm maintenance iCEB in patients with atrial fibrillation (AF). The aim this study was to evaluate AF antiarrhythmic-drug therapy.A total 108 (68 using 40 propafenone) 50 healthy subjects were included study. All groups underwent standard 12-lead surface...

10.14740/cr1185 article EN Cardiology Research 2020-12-12

Background and objective: Arrhythmia is a widely seen cardiologic ailment worldwide, diagnosed using electrocardiogram (ECG) signals. The ECG signals can be translated manually by human experts, but also scheduled to carried out automatically some agents. To easily diagnose arrhythmia, an intelligent assistant used. Machine learning-based automatic arrhythmia detection models have been proposed create assistant. Materials Methods: In this work, we used dataset. This dataset contains 1000...

10.3390/sym13101914 article EN Symmetry 2021-10-11

In the context of coronary artery disease (CAD) pathogenesis, inflammation has emerged as a critical player. This study investigates potential Neutrophil-to-Albumin Ratio (NAR) novel biomarker for assessing CAD severity and extension in patients suffering from acute myocardial infarction (AMI) without ST-segment elevation.

10.26355/eurrev_202312_34781 article EN PubMed 2023-12-01

Objectives: This study aimed to determine whether there is a difference in the electrocardiography (ECG) measurements of healthy controls and rheumatoid arthritis (RA) patients predict they can be used risk arrhythmia patients. Patients methods: The prospective included 50 cardiac asymptomatic RA (38 males, 12 females; mean age: 46.8±9.1 years; range, 18 60 years) who met 2010 American College Rheumatology/European Alliance Associations for Rheumatology criteria volunteers (34 16 43.4±10.4...

10.46497/archrheumatol.2024.10590 article EN Archives of Rheumatology 2024-08-26

Nesfatin-1 was originally identified as a neuropeptide of the hypothalamus, which is key integration area brain, where numerous neuropeptides and transmitters are released to participate in control essential body functions. In literature, there no studies showing relationship between nesfatin-1 level paroxysmal supraventricular tachycardia. We hypothesize that circulating levels may increase during tachycardia, engage vagal stimulation terminate by inhibition neuropeptide-Y, activate...

10.2310/jim.0b013e31828dedd2 article EN Journal of Investigative Medicine 2013-06-01

Our aim was to investigate the apelin-12 levels in patients with atrioventricular tachyarrhythmias and compare those lone atrial fibrillation.Forty four supraventricular tachycardia as fibrillation, 44 paroxysmal (P-SVT) tachyarrhythmias, including nodal reentrant or tachycardia, 30 age- sex-matched healthy individuals were included study.The significantly lower both fibrillation P-SVT groups than control group. In post-hoc analysis, there no significant difference between (P = 0.9)....

10.2459/jcm.0000000000000010 article EN Journal of Cardiovascular Medicine 2014-06-16

Migraine, the most widespread cause of headache in young adults, is a frequent reason for presentation to emergency departments. The aim this study was determine diagnostic value serum galectin-3 and high-sensitivity C-reactive protein (hsCRP) levels migraine patients.Serum hsCRP were measured using enzyme-linked immunosorbent assay 70 patients healthy control subjects.The mean values significantly higher group than those (1.67 ±0.49, 1.12 ±0.38 mg/l, p < 0.001; 3.76 ±1.45, 2.05 ±0.29 ng/ml,...

10.5114/aoms.2016.60984 article EN cc-by-nc-sa Archives of Medical Science 2016-07-22

Abstract Aim To examine subfatin, preptin and betatrophin levels in plasma aqueous patients with diabetes mellitus (DM) (with without retinopathy). Material method Sixty patients, who were similar terms of age gender, scheduled for operation due to cataract, included the study. The divided into three groups as Group C (20 weeks comorbidity), DM but no retinopathy) DR diabetic preoperative body mass index (BMI), fasting glucose, HbA1c, lipid profile all examined. Blood samples also taken...

10.1186/s12886-023-03075-0 article EN cc-by BMC Ophthalmology 2023-07-11
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