A5049826232- Forensic and Genetic Research
- Genetic diversity and population structure
- Digital Humanities and Scholarship
- Hemoglobinopathies and Related Disorders
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Digital Games and Media
- Iron Metabolism and Disorders
- Cancer-related molecular mechanisms research
- Animal Genetics and Reproduction
- Veterinary medicine and infectious diseases
- Epigenetics and DNA Methylation
- Race, Genetics, and Society
- Vector-borne infectious diseases
- Genetic Associations and Epidemiology
- Demographic Trends and Gender Preferences
- Forensic Anthropology and Bioarchaeology Studies
- Prenatal Screening and Diagnostics
- Biomedical Text Mining and Ontologies
- Genomics and Rare Diseases
- Computational and Text Analysis Methods
- Research Data Management Practices
- BRCA gene mutations in cancer
- Data Analysis with R
- Genomics and Phylogenetic Studies
- Contemporary Sociological Theory and Practice
University of Massachusetts Lowell
2016-2019
Murdoch University
2007-2018
University of Otago
2018
Edith Cowan University
2001-2015
University of Illinois Urbana-Champaign
2012-2013
University of Reading
2012
Capital University
2007
Capital Medical University
2007
University of California, San Diego
1991
University of California Davis Medical Center
1989
The symbiotic relationship between legumes and nitrogen fixing bacteria is critical for agriculture, as it may have profound impacts on lowering costs farmers, land sustainability, soil quality, mitigation of greenhouse gas emissions. However, despite the importance symbioses to global cycling balance, very few rhizobial genomes been sequenced so far, although there are some ongoing efforts in sequencing elite strains. In this study, fourteen selected strains order Rhizobiales, all...
Mate choice among early human groups and in many historical populations was subject to both demographic social constraints, ensuring that most unions were between couples who had coinherited substantial proportions of their genomes from common ancestors. Even which close consanguineous marriage proscribed, community endogamy would have been sufficient ensure high levels homozygosity. Consanguineous remains the an estimated 10.4% global population, although there has overall decline its...
The anaerobic spirochete Brachyspira pilosicoli colonizes the large intestine of various species birds and mammals, including humans. It causes "intestinal spirochetosis", a condition characterized by mild colitis, diarrhea reduced growth. This study aimed to sequence analyse bacterial genome investigate genetic basis its specialized ecology virulence.
The anaerobic spirochaete Brachyspira pilosicoli causes enteric disease in avian, porcine and human hosts, amongst others. To date, the only available genome sequence of B. is that strain 95/1000, a isolate. In first intra-species comparison within genus, we report whole B2904, an avian isolate, incomplete WesB, comparisons with 95/1000. We also draw on sequences from three other species. Finally application high-throughput Biolog phenotype screening tool strains for detailed between...
Computational analysis and digital humanities are far from neutral processes sites unimpeded by the political, social economic context in which they emerged utilized. As an interdisciplinary field, have transformed relationship of humans to computers broadly conceived. At same time, methods, theories, perspectives concomitant tools developed being criticized for reproducing divisions that exist society. The effort recover Black women's subjectivities minefield is not without its challenges,...
The intestinal spirochete Brachyspira hyodysenteriae is an important pathogen in swine, causing mucohemorrhagic colitis a disease known as swine dysentery. Based on the detection of significant linkage disequilibrium multilocus sequence data, species considered to be clonal. An analysis genome Western Australian B. strain WA1 has been published, and current study 19 further strains from countries around world were sequenced with Illumina technology. genomes assembled aligned over 97.5%...
To mine large digital libraries in humanistically meaningful ways, scholars need to divide them by genre. This is a task that classification algorithms are well suited assist, but they adjustment address the specific challenges of this domain. Digital pose two problems scale not usually found article datasets used test these algorithms. 1) Because span several centuries, genres being identified may change gradually across time axis. 2) volumes much longer than articles, tend be internally...
Science journalism is a previously neglected but rapidly growing area of scholarship in postgenomics medicine and socio-technical studies knowledge-based innovations. can help evaluate the quantity quality information flux between traditional scientific expert communities broader public, for example, personalized education. Newspapers play crucial role science health communication, more importantly, framing public engagement. However, research on newspaper coverage genomics-related articles...
The widespread geographical distribution of Rhipicephalus decoloratus in southern Africa and its ability to transmit the pathogens causing redwater, gallsickness spirochaetosis cattle makes this hematophagous ectoparasite economic importance. In South Africa, most commonly used chemical acaricides control tick populations are pyrethroids amitraz. current amitraz resistance mechanism described R. microplus, from Australia, involves mutations octopamine receptor, but it is unlikely that will...
While intellectual property protections effectively frame digital humanities text mining as a field primarily for the study of nineteenth century, Internet offers an intriguing object humanists working in later periods. As complex data source, World Wide Web presents its own methodological challenges humanists, but lessons learned from projects studying large century corpora offer helpful starting points. Complicating matters further, legal and ethical questions surrounding web scraping, or...
Genomic data have increasingly been used to complement linguistic, archeological, and anthropological evidence in reconstructing the origins migratory patterns of modern humans. East Asia is a particular hotspot human migration, especially mainland China, where large number fossils unearthed more than 20% world's population now resides. There are 56 officially recognized ethnic populations (minzu) China. In present study we investigated ancestry genetic diversity nine populations: majority...
It is often taken for granted that personal computers today are designed to hide technical information in order make software seem easier. While “transparency of interaction” has influenced popular understandings computer systems, it also shapes our engagement with as critics. This essay examines the origins transparent design different models usability proposed by IBM and Apple response concerns over inaccessibility early 1980s. By tracing how why transparency emerged from this period...
Simplistic by today’s standards, the graphical adventure genre has been overlooked in favor of vast narratives unfolding across more recent three-dimensional virtual worlds and complex social relationships within online environments. Yet this established practices game construction that allow developers to foreground narrative experiences. Graphical games made with Script Creation Utility for Maniac Mansion (SCUMM) engine like Ron Gilbert’s The Secret Monkey Island were among earliest...
Web-based informatics resources for genetic disorders have evolved from genome-wide databases like OMIM and HGMD to Locus Specific (LSDBs) National Ethnic Mutation Databases (NEMDBs). However, with the increasing amenability of diagnosis better management, many previously underreported conditions are emerging as public health significance. In turn, greater emphasis on noncommunicable has generated a demand comprehensive relevant disease-based information end-users, including clinicians,...
A survey of the genetic ancestry 125 Cambodian children resident in Siem Reap province was undertaken, based on eight Y-chromosome binary polymorphisms and sequencing mtDNA HV1 region. The data indicated a largely East Asian paternal local Southeast maternal ancestry. presence Y-chromosomes P* R1a1* suggestive small but significant Indo-European male ancestral component, which probably reflects history Indian, later European, influences Cambodia.
To investigate the proposed historical origins of Hui, a Chinese Muslim minority resident in Liaoning Province, PR China, DNA samples obtained from 53 individuals were analyzed at ten autosomal and six Y-chromosome microsatellite loci. As reference sources, equivalent investigated coresident Han majority population. Both Hui exhibited appreciable genetic heterogeneity terms size, number, size range alleles, suggestive population substructure resulting their particular cultural backgrounds....
Abstract Christmas Island is a remote Australian territory located close to the main Indonesian island of Java. Y‐chromosome and mitochondrial DNA (mtDNA) markers were used investigate genetic structure population, which comprises communities mixed ethnic origin. Analysis 12 biallelic polymorphisms revealed high level gene diversity haplotype frequencies that consistent with source populations in southern China Southeast Asia. mtDNA hypervariable segment I (HVS‐I) sequences displayed levels...