A5090601148- HIV, Drug Use, Sexual Risk
- Cerebrovascular and Carotid Artery Diseases
- Retirement, Disability, and Employment
- Syphilis Diagnosis and Treatment
- Aortic aneurysm repair treatments
- HIV/AIDS Research and Interventions
- Moyamoya disease diagnosis and treatment
- Bioinformatics and Genomic Networks
- Cardiovascular Issues in Pregnancy
Boston Medical Center
2023
University of Virginia
2018
HIV and other sexually transmitted infections (STIs) are on the rise nationally internationally. The coronavirus 2019 (COVID-19) pandemic drove a shift toward telemedicine prioritization of symptomatic treatment over asymptomatic screening. impact in safety-net settings, which faced disproportionate baseline STI/HIV rates rooted structural inequities, where many patients lack resources, is not yet known. This study describes COVID-19 testing at an urban hospital. We used descriptive...
Introduction: Abdominal aortic aneurysm (AAA) rupture has a mortality rate of 64% and intracranial (IA) 50%. Despite the high rates, early detection treatment these vascular lesions prior to can prevent devastating clinical outcomes, underscoring need identify high-risk populations for screening. Current evidence demonstrates shared genetic environmental risk factors both AAA IA. Methods: The BAAS study sought establish co-prevalence In one arm BAAS, we recruited patients presenting with...
Introduction: Recent success identifying genetic variation in ischemic stroke (IS) has yet to translate into actionable targets or pathways. Weighted Gene Co-Expression Network Analysis (WGCNA) uses an unsupervised approach cluster genes modules based on co-expression profiles. Modules likely contain biologically related genes. The correlation between a gene’s expression and the module’s overall pattern (eigengene) defines connectivity. Genes with high connectivity may inform supplement...
Introduction: The pathogenesis of spontaneous cervical artery dissection (sCeAD), a common cause stroke in young adults, is poorly understood. majority published data sCeAD derive from populations European ancestry, including recent genome-wide study identifying an association with the rs9349379 polymorphism PHACTR1 gene. Little known about individuals African ancestry despite robust epidemiological showing increased risk at younger ages, partially explained by higher prevalence traditional...
Introduction: Aneurysm rupture is associated with high mortality and morbidity, including both intracranial aneurysms (IA) abdominal aortic (AAA). Despite potential preemptive treatment in those identified prior to IA or AAA rupture, the evidence for whom screen remains limited. share environmental genetic risk, cost-effectiveness models suggest efficacy of screening these high-risk individuals. We hypothesized that reciprocal presenting would yield positive results. Methods: The BAAS study...