Radzisław Mierzyński

ORCID: 0000-0002-2224-6365
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About
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Research Areas
  • Pregnancy and preeclampsia studies
  • Gestational Diabetes Research and Management
  • Birth, Development, and Health
  • Cardiovascular Issues in Pregnancy
  • Assisted Reproductive Technology and Twin Pregnancy
  • Ovarian cancer diagnosis and treatment
  • Adipose Tissue and Metabolism
  • Diabetes and associated disorders
  • Blood Coagulation and Thrombosis Mechanisms
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Education and Cultural Studies
  • Adipokines, Inflammation, and Metabolic Diseases
  • Cardiovascular, Neuropeptides, and Oxidative Stress Research
  • Regulation of Appetite and Obesity
  • Apelin-related biomedical research
  • Labour Market and Migration
  • Nutrition and Health Studies
  • Catholicism, Bioethics, Media, Education
  • Neonatal Health and Biochemistry
  • Gestational Trophoblastic Disease Studies
  • Fibroblast Growth Factor Research
  • Bariatric Surgery and Outcomes
  • Homicide, Infanticide, and Child Abuse
  • Systemic Lupus Erythematosus Research
  • Reproductive Physiology in Livestock

Medical University of Lublin
2015-2024

Institute of Agrophysics, Polish Academy of Sciences
1996

Gestational diabetes mellitus (GDM) is considered to be one of the most frequent medical complication observed among pregnant women. The role adipokines in pathogenesis GDM remains strictly unknown. Different have been studied throughout gestation, and they proposed as biomarkers other pregnancy-related complications; however, there no biomarker reported for screening at present. aim this study was evaluate serum nesfatin-1 vaspin levels non-GDM women, characterize correlation between these...

10.3390/ijms20010159 article EN International Journal of Molecular Sciences 2019-01-04

The aim of this study was to determine any changes in adiponectin and omentin levels GDM patients who delivered at term preterm evaluate whether adipokines can be useful as a clinical biomarker predict subsequent delivery.The were measured four groups: (1) women with (n=63); (2) had the symptoms threatened labor (n=23); (3) spontaneous birth (before 37 completed weeks gestation) (n=19); (4) physiological pregnancy (n=55).In comparison control group median concentrations significantly lower...

10.1155/2018/7154216 article EN cc-by BioMed Research International 2018-09-18

Fetuses exposed to gestational diabetes mellitus (GDM) have a higher risk of abnormal glucose homeostasis in later life. The molecular mechanisms this phenomenon are still not fully understood. Fatty acid binding protein 4 (FABP4) appears be one the most probable candidates involved pathophysiology GDM. main aim study was investigate whether umbilical cord serum FABP4 concentrations altered term neonates born GDM mothers. Two groups subjects were selected—28 healthy controls and 26 patients...

10.3390/jcm8030285 article EN Journal of Clinical Medicine 2019-02-27

The exact role of adipokines in the pathogenesis gestational diabetes mellitus (GDM) still remains not fully clear, and multiple studies have analyzed their potential contribution to pathophysiology this pregnancy complication. This study is aimed at evaluating serum chemerin, lipocalin 2, apelin concentrations GDM healthy pregnant patients, assessing correlation between these adipokines, suggesting cytokines diagnosis GDM. comprised 237 women: 153 with 84 physiological pregnancy. Serum were...

10.1155/2021/5547228 article EN cc-by Journal of Diabetes Research 2021-06-09

Women with a previous history of gestational diabetes mellitus (GDM) have significantly increased risk developing type 2 diabetes, obesity, and cardiovascular diseases in the future. The aim study was to evaluate ghrelin concentrations serum urine GDM group early post-partum period, reference laboratory results, body composition, hydration status. subjects were divided into two groups, that is, 28 healthy controls 26 patients diagnosed GDM. maternal composition status evaluated by...

10.3390/ijms19103001 article EN International Journal of Molecular Sciences 2018-10-01

Abstract Aim: (1) To evaluate the prevalence of inherited thrombophilia in pregnant women with adverse pregnancy outcomes: intrauterine growth retardation (IUGR), preeclampsia (PE) and placental abruption. (2) assess impact on nature obstetric complications. (3) levels protein S, C, antithrombin III homocysteine outcomes. Subjects methods: The study comprised 162 women. patients were divided into three test groups one control group. In all following tests completed: activated C resistance...

10.1515/jpm-2017-0059 article EN Journal of Perinatal Medicine 2017-08-09

The aim of the study was to evaluate concentrations soluble intercellular adhesion molecule-1 (s-ICAM-1) and endogenous NOS inhibitor, asymmetric dimethylarginine (ADMA), as markers endothelium dysfunction in patients with gestational diabetes mellitus (GDM).The levels s-ICAM-1 ADMA were analysed group 56 GDM compared 25 healthy pregnant women. measured serum using ELISA tests.The groups did not differ by baseline descriptors: age (30.75 ± 6.32 versus 28.50 4.95 years, NS) (28.96 2.85 29.12...

10.1155/2016/1342643 article EN cc-by Journal of Diabetes Research 2016-01-01

The aim of the study was to evaluate levels adipokines such as adiponectin and leptin well soluble intercellular adhesion molecule-1 (sICAM-1) endogenous NOS inhibitor-asymmetric dimethylarginine (ADMA), endothelium dysfunction markers in pregnant women with gestational hypertension (GH). Adiponectin, leptin, sICAM-1, ADMA concentrations were measured a group 34 patients GH 32 healthy between 24th 34th week gestation ELISA tests. compared ones characterized by significantly higher BMI (28.09...

10.1155/2019/7541846 article EN cc-by International Journal of Hypertension 2019-10-13

Gestational diabetes mellitus (GDM) is one of the most common medical disorders in pregnancy. Adipokines, predominantly secreted by adipose tissue, are involved numerous metabolic processes. The exact role adipokines pathogenesis GDM still not well known, and have been analysed throughout pregnancy proposed as biomarkers GDM. This study aimed to evaluate serum adiponectin, chemerin, lipocalin apelin levels non-GDM women, assess them clinically useful occurrence demonstrate correlation...

10.3390/ijms25010175 article EN International Journal of Molecular Sciences 2023-12-22

Objectives: The aim of the study was to evaluate levels adipokines such as adiponectin, resistin, leptin well C-peptide in overweight and obese pregnant women. Material methods: concentrations were measured group 38 overweight/obese women (BMI > 25 kg/m2) 42 normal weight < with ELISA tests between 24th 34th weeks gestation. Results: compared lean ones characterized by significantly higher (43.44 ± 31.41 vs. 21.29 12.67 ng/mL, p = 0.0001) (2.77 1.88 2.25 1.42 0.034). There no significant...

10.5603/gp.a2018.0076 article EN cc-by-nc-nd Ginekologia Polska 2018-08-31

Summary The aim of the following study was comparison phospholipase A 2 (PLA ) activity and fatty acids content in cows with without retained fetal membranes. enzyme levels were measured maternal placental tissues obtained from immediately after spontaneous parturition (group A) B) PLA statistically significantly (P &lt; 0.05) higher group than B, lower part placenta both groups. examined –‐ myristic (14:0), palmitic (16:0), palmitoleic (16:1), stearic (18:0), oleic (18:1), linolenic (18:3),...

10.1111/j.1439-0442.1996.tb00475.x article EN Journal of Veterinary Medicine Series A 1996-02-12
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