A5071366116- Inflammasome and immune disorders
- Autoimmune and Inflammatory Disorders Research
- Kawasaki Disease and Coronary Complications
- Vasculitis and related conditions
- Ocular Diseases and Behçet’s Syndrome
- Renal Diseases and Glomerulopathies
- Adolescent and Pediatric Healthcare
- Streptococcal Infections and Treatments
- Otitis Media and Relapsing Polychondritis
- Systemic Lupus Erythematosus Research
- Retinal and Optic Conditions
- IgG4-Related and Inflammatory Diseases
- Osteomyelitis and Bone Disorders Research
- Spondyloarthritis Studies and Treatments
- Complement system in diseases
- Hematological disorders and diagnostics
- Systemic Sclerosis and Related Diseases
- Dermatological and COVID-19 studies
- Urticaria and Related Conditions
- Orthopedic Infections and Treatments
- IL-33, ST2, and ILC Pathways
- Infectious Diseases and Tuberculosis
- Mechanical Circulatory Support Devices
- interferon and immune responses
- Immunodeficiency and Autoimmune Disorders
Ministry of Health
2020-2025
Bilkent University
2021-2024
Sağlık Bilimleri Üniversitesi
2020-2024
ORCID
2023
Memorial Ankara Hospital
2020-2023
Kaplan (United States)
2023
Ankara Mevki Asker Hastanesi
2021-2023
Ankara Bilkent City Hospital
2023
University of Health Science
2021-2023
University of Health Sciences
2021-2023
Abstract Aims Recently, multisystem inflammatory syndrome in children (MIS‐C) has been recognized association with coronavirus disease 2019 as a cytokine storm syndrome. MIS‐C presents symptoms similar to Kawasaki and macrophage activation (MAS). We aimed better understand this by comparing the initial laboratory findings of MAS. Methods Patients who were diagnosed MAS due systemic juvenile idiopathic arthritis our clinic between March 2002 November 2020 20 September October enrolled into...
The aims of this study were to evaluate the role biological agents in treatment severe multisystem inflammatory syndrome children (MIS-C) and assess current application, outcomes, adverse effects patients who are followed up a pediatric intensive care unit (PICU).This observational, descriptive, medical records review was performed on with MIS-C admitted PICU between September 1 November 1, 2020. Through review, we confirmed that positive for or recent SARS-CoV-2 infection COVID-19 exposure...
Abstract Aim The aim of this study is to evaluate the clinical parameters, acute‐phase reactants, side effects, genetic mutations among colchicine‐resistant Familial Mediterranean fever (FMF) patients who received anti‐interleukin‐1 (anti‐IL‐1) treatment. We also quality life and school attendance FMF patients, in relation treatment with anti‐IL‐1. Introductıon most common inherited autoinflammatory disorder. Although main colchicine, a small group are resistant colchicine Anti‐IL‐1...
To compare enthesitis-related arthritis (ERA) patients with active and inactive disease at 6 months define baseline predictors for inactivity. In addition, to evaluate the demographic, clinical, laboratory characteristics of ERA identify real-life impact Juvenile Spondyloarthritis Disease Activity Index (JSpADA) in predicting ERA.This medical record review study was conducted 56 who were diagnosed our clinic between June 2009 2022. Demographic clinical characteristics, parameters, treatment,...
Behçet's disease (BD) is a multisystem and frequently occurs during the second-fourth decades of life, although onset may be seen at any age. This study aimed to analyze influence age on clinical manifestations BD.This retrospective analyzed two cohorts (paediatric adult) determine association between features in BD. Patients were classified into four groups characteristics according fulfilling BD diagnostic criteria as follows: childhood (<12 years), adolescent (13-17 adult (18-39 late (>40...
Chronic non-bacterial osteomyelitis is a chronic sterile inflammatory bone condition. We aimed to describe patients' clinical and radiographic findings evaluate their response therapy quality of life.This cross-sectional study included 18 patients from single center in Turkey whose clinical, radiological features, outcomes were reviewed retrospectively. The the lives after treatment was compared with healthy controls using Pediatric Quality Life Inventory 4.0.The median age disease onset 12...
The aim of this study is to describe clinical features patients with oligoarticular juvenile idiopathic arthritis (JIA) who achieved inactive disease at 3rd month and also determine the predictors relapse extended course.In cohort study, 88 JIA were retrospectively analyzed. demographic data, features, medications, rates recorded. Juvenile Arthritis Disease Activity Score (JADAS) American College Rheumatology Pediatric criteria used measure activity treatment response 3, 6 12...
The aims of this study were to describe the clinical features, comorbidities and outcome systemic childhood polyarteritis nodosa (PAN) evaluate PAN-like diseases in differential diagnosis.The group consisted patients who diagnosed as PAN a referral center Turkey. files all reviewed retrospectively. Disease activity was evaluated with pediatric vasculitis score (PVAS).A total 19 (13 boys/six girls) enrolled study. mean age 10.37 ± 3.6 years. duration follow-up 5.73 3.74 Eight (42.1%) also...
The purpose of this study was to compare the demographic, clinical and laboratory characteristics patients with enthesitis-related arthritis (ERA), familial Mediterranean fever (FMF) inflammatory bowel disease (IBD), which are diseases that may develop sacroiliitis. Thus, it aimed reveal various findings indicate primary in sacroiliitis.Pediatric aged 6-18 years, who were being followed a diagnosis ERA (n = 62), FMF 590), IBD 56) over period 2013-2021 included study. Sacroiliitis 55)...
ABSTRACT Objectives The aim of this study is to evaluate differences in school performance, attendance, quality life, and physical activity adolescents with Familial Mediterranean fever (FMF) compared healthy controls. Methods One hundred twenty-nine patients FMF 154 controls between 13 18 years were included the study. Demographic, performance (according grade point average), absenteeism, type frequency exercise recorded. Quality life was evaluated Pediatric Life Inventory (PedsQL) 4.0....
Background The Eurofever/the Pediatric Rheumatology International Trials Organization (PRINTO) classification criteria for familial Mediterranean fever (FMF) include a combination of clinical symptoms and genotype. pathogenicity gene variants associated with FMF is categorized by the Study Group Systemic Autoinflammatory Diseases (INSAID) criteria. Objective aim this study was to evaluate real-life impact usefulness Eurofever/PRINTO INSAID in patients their on treatment management. Methods...
AimTo evaluate the treatment response to compressed colchicine tablets in familial Mediterranean fever (FMF) patients with resistance or intolerance coated colchicine. The secondary aim was determine demographic and clinical characteristics of responders colchicine.MethodsWe retrospectively reviewed medical records 1574 pediatric FMF treated at Ankara Bilkent City Hospital. Sixty-one did not respond were switched In these patients, number attacks International Severity Score for (ISSF)...
The present study aimed to compare the demographic, clinical, and laboratory characteristics of patients with pediatric Behçet disease (BD) without thrombosis elucidate factors that may contribute development thrombosis.This observational, descriptive, medical records review included BD (n = 85) who were diagnosed at age younger than 16 years our clinic between 2010 2022. available data compared. potential risk for evaluated multivariable logistic regression analysis.Central venous sinus was...
Coronavirus disease 2019 (COVID-19), which causes severe acute respiratory syndrome, was accepted as a pandemic by the World Health Organization in March 2020. Some of rheumatological diseases develop on basis immune system disorders such autoimmunity and it is known that use immunosuppressive drugs increases risk infection.1, 2 Therefore, early stages COVID-19 outbreak, condition patients receiving treatments biologics because has raised concerns.2 We aim to investigate exposure who...
Objective To compare the demographic and clinical characteristics of familial Mediterranean fever (FMF) patients according to age at disease onset evaluate dose effect number pathogenic or likely exon 10 mutations MEFV gene on severity.