A5007712771- Neonatal Health and Biochemistry
- Organ Donation and Transplantation
- Renal Diseases and Glomerulopathies
- Erythrocyte Function and Pathophysiology
- Hematopoietic Stem Cell Transplantation
- Polyomavirus and related diseases
- Complement system in diseases
- Pancreatitis Pathology and Treatment
- Parvovirus B19 Infection Studies
- Organ Transplantation Techniques and Outcomes
- Genetic and Kidney Cyst Diseases
- Acute Lymphoblastic Leukemia research
- Hemoglobinopathies and Related Disorders
- Muscle and Compartmental Disorders
- Biomedical Research and Pathophysiology
- Inflammasome and immune disorders
- Cardiac Ischemia and Reperfusion
- Pharmacological Effects and Toxicity Studies
- Anesthesia and Neurotoxicity Research
- Neonatal Respiratory Health Research
- Peptidase Inhibition and Analysis
- Ureteral procedures and complications
- Methemoglobinemia and Tumor Lysis Syndrome
- Antibiotics Pharmacokinetics and Efficacy
- Vasculitis and related conditions
Başkent University
2018-2024
Sağlık Bilimleri Üniversitesi
2024
Ankara Bilkent City Hospital
2024
Başkent University Hospital
2023
Memorial Ankara Hospital
2022
ABSTRACT Background Two earthquakes on 6 February 2023 destroyed 10 cities in Türkiye. We report our experience with pediatric victims during these catastrophes, a focus crush syndrome related–acute kidney injury (Crush-AKI) and death. Method Web-based software was prepared. Patient demographics, time under rubble (TUR), admission laboratory data, dialysis, overall outcomes were recorded. Results A total of 903 injured children (median age 11.62 years) evaluated. Mean TUR 13 h (interquartile...
BK polyomavirus infection is a critical complication affecting graft survival after kidney transplant. We aimed to determine the frequency, effect on function, and risk factors of in pediatric transplant patients.We retrospectively reviewed data 144 patients (female/male: 67/77; 0-18 years age) who received transplants past 10 at our center. Demographic/ laboratory data, failure etiologies, donor types, immunosuppressive treatments were recorded. Patients grouped as those with without BKV...
Objective: It is unclear whether exon 2 mutations are variations or a that causes the disease. This study aimed to evaluate clinical features and prognosis in Familial Mediterranean Fever. Methods: The features, disease severity of all patients with at least one were evaluated retrospectively. These data compared seperately for homozygous (Group 1), heterozygous 2), compound 3), complex alleles 4), by grouping into those without 10 mutations. Results: There total 119 mutations, including...
Introduction Juvenile nephronophthisis (NPHP), an autosomal recessive tubulointerstitial nephropathy, accounts for 10%–20% of renal failure cases in childhood. Treatment patients with NPHP is symptomatic. Kidney transplantation the treatment choice when ESRD established. We report herein our center's experience kidney children juvenile NPHP. Materials and Methods retrospectively analyzed medical records 142 transplant patients. compared donor types, dialysis modality duration,...
Aims Severe reduction in nephron numbers that are characteristic of renal hypodysplasia (RHD) one the cause childhood chronic kidney disease (CKD). Glomerular hyperfiltration, glomerular hypertrophy, progressive scarring, and interstitial fibrosis due to reduced number risk factors for CKD. In recent years, studies on specific markers early diagnosis failure mortality have been carried out. The objectives this study were identify serum urinary endocan levels expressed endothelial cells...
Abstract Background Acute kidney injury (AKI) is common complication of hematopoietic stem cell transplantation (HSCT) with increased mortality and morbidity. Understading the risk factors for AKI essential. The aim this study to identify incidence, factors, prognosis in pediatric post- HSCT patients. Methods We conducted a retrospective case-control 278 patients who were divided into two groups: those without (Non-AKI). groups compared terms characteristics clinical symptoms patients,...
Introduction: Cystinosis is a rare genetic, lysosomal storage disorder, leading to kidney involvement and other organs. The most critical factor determining the prognosis its impact on kidneys especially nephropatic cystinosis. This study aimed evaluate cystinosis patients identify factors associated with chronic disease (CKD).
 Methods: medical records of 18 were retrospectively reviewed. Demographic clinical features, evaluated. Patients classified according their estimated glomerular...
Introduction Chronic kidney disease (CKD) has increased risk for cardiovascular morbidity and mortality. CKD evokes structural functional cardiac changes such as left ventricular hypertrophy (LVH), LV dilatation, systolic diastolic dysfunction. Increased blood pressure, volume overload in particular the uremic milieu with its toxins contribute to these alterations. Restoration of renal function after transplantation (RT) disrupts negative cardiorenal interplay may reverse some seen CKD. The...
Introduction Anemia is commonly observed in early post-transplant period. Blood transfusion the most frequent using procedure correction of anemia. However post transplant blood transfusions may increase immunological risks, antibody formation and rejection. There little information on impact children. We aimed to evaluate effects graft outcome pediatric renal recipients Materials Methods retrospectively evaluated data 97 patients. Demographic patients, etiology failure, donor types,...
Introduction BK virus-associated nephropathy is an increasing problem in renal transplant recipients. Untreated virus (BKV) infections lead to kidney allograft dysfunction or loss. Decreased immunosuppression the principle treatment but predisposes acute and chronic rejection. Screening for early detection prevention of symptomatic BKV may improve outcomes. The purpose this study was determine incidence, clinical features risk factors infection (viruria, viraemia, nephropathy) pediatric...
The association between vitamin D deficiency and anemia is known. Vitamin are common in kidney transplant recipients. We examined the relationship levels pediatric recipients.We reviewed retrospectively data of 75 recipients (0-18 years age). Patients were evaluated 3 groups according to serum 25-hydroxyvitamin (<20, 20-30, >30 ng/mL) first year posttransplant: group 1 was group, 2 insufficiency normal level respectively. Groups compared terms parameters, calcium, phosphorus, alkaline...
Nephronophthisis is the most common genetic cause of kidney failure in childhood. Treatment for nephronophthisis symptomatic, and transplant a good treatment option when has developed. We reported outcomes recipients with primary diagnosis juvenile who were followed-up our center.We retrospectively examined medical records 17 patients nephronophthisis. compared this group had other etiologies terms age, donor type, immunosuppressive treatment, acute rejection, graft loss rates, glomerular...