A5045942414- Pediatric Urology and Nephrology Studies
- Urinary Tract Infections Management
- Inflammasome and immune disorders
- Urological Disorders and Treatments
- Urinary Bladder and Prostate Research
- Renal Diseases and Glomerulopathies
- Vasculitis and related conditions
- Regulation of Appetite and Obesity
- Kidney Stones and Urolithiasis Treatments
- Iron Metabolism and Disorders
- Sepsis Diagnosis and Treatment
- Electrolyte and hormonal disorders
- Immune Response and Inflammation
- Systemic Lupus Erythematosus Research
- Infectious Encephalopathies and Encephalitis
- Neonatal Health and Biochemistry
- Adipokines, Inflammation, and Metabolic Diseases
- Ion Transport and Channel Regulation
- Herpesvirus Infections and Treatments
- Autoimmune and Inflammatory Disorders
- Ocular Diseases and Behçet’s Syndrome
- Skin Diseases and Diabetes
- COVID-19 and healthcare impacts
- Acute Kidney Injury Research
- Virology and Viral Diseases
Fırat University
2013-2025
Gazi University
2022
Erciyes University
2006-2010
Pediatric Nephrology of Alabama
2010
Istanbul University
2008
Insulin‐dependent diabetes mellitus (IDDM) is a chronic disease characterized by T‐cell‐dependent autoimmune destruction of the insulin‐producing β cells in pancreatic islets Langerhans, resulting an absolute lack insulin. T are activated response to islet‐dominant autoantigens, result being development IDDM. Insulin one islet autoantigens responsible for activation T‐lymphocyte functions, inflammatory cytokine production, and The aim this study was investigate serum concentrations...
Endothelial dysfunction is an important factor in the pathogenesis of atherosclerosis, and endothelial microparticles (EMPs) are considered as markers dysfunction. In this study, we aimed to examine relationship between EMPs arterial stiffness atherosclerosis children with chronic kidney disease (CKD).This cross-sectional study included 37 dialysis patients (12 haemodialysis, 25 peritoneal dialysis), 33 pre-dialysis 18 healthy controls. Both vivo vitro (HUVECs) evaluations were used for...
It has not yet been shown in prepubertal children how cytokines, leptin, and body mass, as well parameters of obesity are interrelated. The aim this study was to explore the relation between circulating levels some cytokines with leptin mass index. A case control carried out obese both sexes. An group 63 school a comprised same number nonobese paired by age sex. Mean serum concentration significantly higher at 19.9 ± 7.4 ng/mL, than (7.9 5.1 ng/mL). Serum IL‐1 β , IL‐6, TNF‐ α were also...
The aim of the present study was not only to review clinical and demographic features child-onset familial Mediterranean fever (FMF) patients but also investigate whether there is a phenotype-genotype correlation in same patient population.The medical records 102 with FMF were retrospectively reviewed. Patients classified into three groups according mutations: group 1, Met694Val-Met694Val (homozygote); 2, Met694Val-other; 3, other-other. These compared regard gender, age onset, diagnosis,...
ABSTRACT Background Two earthquakes on 6 February 2023 destroyed 10 cities in Türkiye. We report our experience with pediatric victims during these catastrophes, a focus crush syndrome related–acute kidney injury (Crush-AKI) and death. Method Web-based software was prepared. Patient demographics, time under rubble (TUR), admission laboratory data, dialysis, overall outcomes were recorded. Results A total of 903 injured children (median age 11.62 years) evaluated. Mean TUR 13 h (interquartile...
Cyclophosphamide (CYC) is an inactive alkylating agent that transforms the alkyl radicals into other molecules and used in combination with systemic corticosteroids treatment of many childhood rheumatic diseases, such as lupus erythematosus (SLE), ANCA-associated vasculitis (AAV). In recent years, rituximab (RTX), a B-cell-targeting anti-CD20 monoclonal antibody, has emerged new alternative modality over CYC for induction therapy childhood-onset diseases. Clinicians adopt different practices...
This study aimed to evaluate the predictability of homozygous M694V genotype in pediatric familial Mediterranean fever (FMF) patients and develop a clinical scoring system enhance disease management strategies. nationwide, multicentre, cross-sectional included 3,981 FMF with biallelic pathogenic variants exon 10 Fever gene. Patients were divided into two groups: group 1 (homozygous M694V) 2 (other variants). Data collected from 37 rheumatology and/or nephrology clinics across Türkiye,...
The aim of present study was to evaluate the indications, complications and outcomes acute peritoneal dialysis (APD) in neonates at a referral university hospital during previous 8 years.This retrospective analysis included total 52 newborn infants who underwent APD neonatal intensive care unit between January 2008 March 2016. Demographic, clinical, laboratory microbiological data were extracted from patients' medical files.The primary causes for requiring tubular necrosis (n = 36, 69.2%),...
Infantile nephropathic cystinosis is a severe disease that occurs due to mutations in the gene, and it characterized by progressive dysfunction of multiple organs; >100 gene have been identified populations. Our study aimed identify clinical characteristics spectrum Turkish pediatric patients with cystinosis.We multicenter registry was established for data collection. The were extracted from this analyzed.In total, 136 (75 men 61 women) enrolled study. most common findings growth...
Cocklebur (Xanthium strumarium) is an herbaceous annual plant with worldwide distribution. The seeds contain the glycoside carboxyatractyloside, which highly toxic to animals. We describe nine cases of carboxyatractyloside poisoning in humans which, our knowledge, has not previously been reported. clinical, laboratory and histopathological findings therapeutic approach are also discussed.The patients presented acute onset abdominal pain, nausea vomiting, drowsiness, palpitations, sweating...
Objectives Ghrelin stimulates food intake and induces metabolic changes leading to an increase in body weight fat mass. Iron-deficiency anemia (IDA) is the most frequently seen cause of nutritional anemia, that a type starvation. There no available study related levels ghrelin IDA. The aim this show association with iron deficiency demonstrate whether (ID) are explained by ghrelin, as opposed correlate ID. Materials Methods group was consisted children who were admitted outpatient clinic...
Background Predicting vesico-ureteral reflux (VUR) ≥3 at the time of first urinary tract infection (UTI) would make it possible to restrict cystography high-risk children. We previously derived following clinical decision rule for that purpose: should be performed in cases with ureteral dilation and a serum procalcitonin level ≥0.17 ng/mL, or without dilatation when ≥0.63 ng/mL. The yielded 86% sensitivity 46% specificity. aimed test its reproducibility. Study Design A secondary analysis...
Abstract Background: Determining uric acid : creatinine ratios in random urine samples may be useful to assess the excretion of children. Because it was shown that urinary varies with age and geographic area, is important have accurate reference values excretion. The aim present study therefore obtain regional for healthy Turkish Methods: A total 1306 children aged 1 month–15 years were analyzed creatinine, determined from each sample. second non‐fasting morning taken all Urine using uricase...
Abstract Background To evaluate the clinical features of patients with multicystic dysplastic kidney ( MCDK ). Methods The medical files children diagnosed between January 2008 and November 2015 were retrospectively reviewed. demographic, clinical, laboratory radiological data evaluated. Results Of 128 enrolled in study, 82 (64.1%) male, 46 (35.9%) female P < 0.05). located on left right sides 66 (51.6%) 62 (48.4%), respectively > Antenatal diagnosis was present 64 (50%). mean age at...
The pathogenesis of edema in nephrotic syndrome is not entirely understood. aim this study was to contribute the discussion on by following changes volume and sodium retention for course disease children with steroid-sensitive (SSNS).Forty-one SSNS were included study. patients divided into three groups (group I: relapse-edematous; group II: relapse-edema free; III: remission). We investigated value significance area vasoactive hormones. In addition, we measured parameters such as inferior...