İbrahim Gökçe
- Pediatric Urology and Nephrology Studies
- Renal Diseases and Glomerulopathies
- Renal and related cancers
- Complement system in diseases
- Urological Disorders and Treatments
- Kidney Stones and Urolithiasis Treatments
- Genetic and Kidney Cyst Diseases
- Biomedical Research and Pathophysiology
- Renal and Vascular Pathologies
- Urinary Tract Infections Management
- Urinary Bladder and Prostate Research
- Vasculitis and related conditions
- Genetic Syndromes and Imprinting
- Ion Transport and Channel Regulation
- Inflammasome and immune disorders
- Dialysis and Renal Disease Management
- Neonatal Respiratory Health Research
- Vascular anomalies and interventions
- Parathyroid Disorders and Treatments
- Iron Metabolism and Disorders
- Neonatal Health and Biochemistry
- Renal cell carcinoma treatment
- Magnesium in Health and Disease
- Bladder and Urothelial Cancer Treatments
- Celiac Disease Research and Management
Marmara University
2016-2025
Kent Hastanesi
2023
Acıbadem Adana Hospital
2023
Pediatrics and Genetics
2022-2023
Pediatric Nephrology of Alabama
2017-2019
KU Leuven
2019
Ankara University
2015
Erzurum Regional Training and Research Hospital
2012
Turkish Armed Forces
2009-2011
New York Academy of Medicine
2011
Objective: Serum alkaline phosphatase (ALP) levels show great variation with age and sex in children adolescents.Additionally, different buffers used even the same method cause variable results.This detail is not usually taken into account evaluation.We aimed to study pediatric age-and sex-specific reference ranges for ALP by colorimetric assay using p-nitrophenyl phosphate as substrate diethanolamine buffer also compare patients types of rickets.Methods: 1741 healthy adolescents (904 girls)...
Introduction: Listeria monocytogenes is a Gram-positive bacillus that causes severe infections mainly in newborns, pregnant women, immunocompromised individuals, and elderly. In this report, we present case of immune dysregulation presented with invasive infection despite the absence these risk factors. Case: A previously healthy 5-year-old girl developed L. meningitis, which unusual given her age lack typical The patient initially fever, diarrhea altered mental status, unresponsive to...
Infantile nephropathic cystinosis is a severe disease that occurs due to mutations in the gene, and it characterized by progressive dysfunction of multiple organs; >100 gene have been identified populations. Our study aimed identify clinical characteristics spectrum Turkish pediatric patients with cystinosis.We multicenter registry was established for data collection. The were extracted from this analyzed.In total, 136 (75 men 61 women) enrolled study. most common findings growth...
Abstract Autosomal recessive polycystic kidney disease (ARPKD) is characterized by bilateral fibrocystic changes resulting in pronounced enlargement. Impairment of function highly variable and widely available prognostic markers are urgently needed as a base for clinical decision-making future trials. In this observational study we analyzed the longitudinal development sonographic measurements cohort 456 ARPKD patients from international registry ARegPKD. We furthermore evaluated...
Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic cause of renal failure. For several decades, ADPKD was regarded as an adult-onset disease. In past decade, it has become more widely appreciated that course begins in childhood. However, evidence-based guidelines on how to manage and approach children diagnosed with or at risk are lacking. Also, scoring systems stratify patients into categories have been established only for adults. Overall, there insufficient...
To test the association between bilateral nephrectomies in patients with autosomal recessive polycystic kidney disease (ARPKD) and long-term clinical outcome to identify risk factors for severe outcomes, a dataset comprising 504 from international registry study ARegPKD was analyzed characteristics complications of very early (≤ 3 months; VEBNE) (4-15 EBNE) nephrectomies. Patients dialysis (VED, onset ≤ months) without total volumes (TKV) comparable VEBNE infants served as additional control...
Autosomal recessive polycystic kidney disease (ARPKD) is a rare monogenic disorder characterized by early onset fibrocystic hepatorenal changes. Previous reports have documented pronounced phenotypic variability even among siblings in terms of patient survival. The underlying causes for this clinical are incompletely understood.We present the longitudinal courses 35 sibling pairs included ARPKD registry study ARegPKD, encompassing data on primary manifestation, prenatal and perinatal...
Abstract Background Primary nephrogenic diabetes insipidus (NDI) is a rare disorder and little known about treatment practices long-term outcome. Methods Paediatric adult nephrologists contacted through European professional organizations entered data in an online form. Results Data were collected on 315 patients (22 countries, male 84%, adults 35%). Mutation testing had been performed 270 (86%); pathogenic variants identified 258 (96%). The median (range) age at diagnosis was 0.6 (0.0–60)...
Acute tubulointerstitial nephritis (TIN) is a significant cause of acute renal failure in paediatric and adult patients. There are no large series focusing on the aetiology, treatment courses TIN.We collected retrospective clinical data from patients with biopsy-proven TIN by means an online survey. Members four professional societies were invited to participate.Thirty-nine physicians 18 countries responded. 171 included (54% female, median age 12 years). The most frequent causes uveitis...
The causative agent spectrum and resistance patterns of urinary tract infections in children are affected by many factors.To demonstrate antibiotic changing ratio years.Retrospective cross-sectional study.We analysed isolated Gram (-) bacteria during the years 2011-2014 (study period 2) with infections. We compared these findings data collected same centre 2001-2003 1).Four hundred sixty-five uncomplicated community-acquired were from 400 2011-2014. Sixty-one percent patients female (1.5...