A5038975429- Inflammasome and immune disorders
- Systemic Lupus Erythematosus Research
- Autoimmune and Inflammatory Disorders Research
- IL-33, ST2, and ILC Pathways
- Rheumatoid Arthritis Research and Therapies
- Kawasaki Disease and Coronary Complications
- Gout, Hyperuricemia, Uric Acid
- interferon and immune responses
- Shoulder Injury and Treatment
- Cholesterol and Lipid Metabolism
- Skin and Cellular Biology Research
- Dermatological and Skeletal Disorders
- Immune Cell Function and Interaction
- Tendon Structure and Treatment
- T-cell and B-cell Immunology
- Monoclonal and Polyclonal Antibodies Research
- Platelet Disorders and Treatments
- Systemic Sclerosis and Related Diseases
- Vasculitis and related conditions
- Sports injuries and prevention
- Adolescent and Pediatric Healthcare
- Elbow and Forearm Trauma Treatment
Ümraniye Eğitim ve Araştırma Hastanesi
2023-2025
Sağlık Bilimleri Üniversitesi
2023-2025
University of Health Science
2024
Center for Rheumatology
2023
Objective In this study, we aimed to evaluate the characteristics of pediatric rhupus patients including all related series in literature. Methods Thirty with syndrome from 12 different centers Turkey were included study. The literature was also reviewed for syndrome. Results most prominent phenotype these 30 juvenile idiopathic arthritis (JIA) (60%) at disease onset and SLE (73.3%) last visit. Major SLE-related organ involvements skin (80%), hematological system (53.3%), kidney (23.3%)....
ABSTRACT Aim In this study, we aimed to evaluate and compare the characteristics of pediatric adult rhupus patients. Methods Thirty patients with syndrome 15 were included in study. Similarities differences between both groups evaluated. Results The time elapsed diagnosis juvenile idiopathic arthritis (JIA)/rheumatoid (RA) systemic lupus erythematosus (SLE) was longer adults than ( p < 0.001). While most common phenotypes at disease onset JIA/RA children, SLE more prevalent RA last visit...
To assess the phenotypic characteristics of patients carrying variants uncertain significance (VUS) in Mediterranean fever (MEFV) gene. The study included only VUS MEFV Patients were excluded if they did not meet pediatric criteria for familial (FMF). assigned to homozygous, compound heterozygous, or heterozygous groups according their genotype. Additionally, analyses conducted based on specific genotypes. A total 2,326 gene records reviewed. Of these, 310 (F : 152/M 158) met inclusion...
Abstract Objectives Colchicine forms the mainstay of treatment in FMF. Approximately 5–10% FMF patients are colchicine resistant and require anti-IL-1 drugs. We aimed to compare characteristics colchicine-resistant colchicine-responsive develop a score for predicting resistance at time diagnosis. Methods (0–18 years) enrolled Turkish Paediatric Autoinflammatory Diseases (TURPAID) registry were included. The predictive was developed by using univariate/multivariate regression receiver...
Abstract Objectives The aim of this study is to investigate the effect anti-interleukin (IL)-1/-6 biologics on systemic juvenile idiopathic arthritis (sJIA)-associated macrophage activation syndrome (MAS). Methods Demographic, clinical and laboratory data patients followed up with a diagnosis sJIA-associated MAS assessed from sixteen paediatric rheumatology centres across country. features developing while biological drugs were compared those without treatment. Results One hundred sixty-two...
IgA vasculitis (IgAV) is a multisystemic small vessel and the most common in childhood. The characteristic findings of IgAV are palpable purpuric rash, abdominal pain, arthralgia or arthritis, hematuria. Ischemic complications very rare IgAV. Thrombotic can be observed after COVID-19 infection. Also presence familial Mediterranean fever, may have an atypical more severe course.We present case complicated with renal infarction intestinal ischemia. There was no recent distant history patient...
Objective The aim of this study was to characterize childhood-onset systemic lupus erythematosus (SLE) in two large cohorts from Turkey and the United States. Methods Patients diagnosed with SLE who fulfilled 1997 American College Rheumatology classification criteria for four reference centers University Pittsburgh School Medicine States were included study. A comparative analysis conducted evaluate similarities differences clinical laboratory features, damage accrual, treatment experiences...
Background: Although clinical assessment has historically been the primary method used for pediatric localized sclerosis (LS) diagnosis and staging, highfrequency ultrasonography (HFUS) is being investigated as a more accurate evaluation lesion. Objectives: This study aimed to assess, compare dermal subcutaneous tissue characteristics enhance lesion staging in LS patients using HFUS. Methods: Twenty two were cross-sectionally evaluated with B-mode ultrasonography. Lesions clinically staged,...
Ultrasonographic evaluation of changes in the joint before and after intra-articular injection children with juvenile idiopathic arthritis
Abstract Objectives This study aims to establish normative data on lower extremity entheseal tendon thicknesses in healthy children and examine correlations with age, gender, anthropometric measures using musculoskeletal ultrasound. The secondary objective of the is investigate power Doppler properties tendons. Methods A total 192 children, aged 5–18 years, participated this cross-sectional study. Participants underwent detailed physical ultrasonographic examinations. Entheseal thickness...
Objective The aim of this study was to identify key parameters a scoring system be developed predict the homozygous M694V genotype in patients clinically diagnosed with familial Mediterranean fever. Methods This cross-sectional analysis 472 pediatric fever on exon 10, followed at our tertiary rheumatology clinic between June 2016 and 2023. were categorized into 2 groups based their genotypes: group 1 comprised 402 (85.2%) genotype, whereas consisted 70 (14.8%) other genotypes. Demographic...
Systemic lupus erythematosus (SLE) due to anti-tumor necrosis factor (TNF) agents is a rare entity. We reported three cases who developed lupus-like syndrome while receiving infliximab therapy for various reasons. All demonstrated clinical and laboratory findings of SLE. And all them needed treatment. would like emphasize that the risk anti-TNF-alpha-induced should be kept in mind patients anti-TNF any reason.
Systemic lupus erythematosus (SLE) due to anti-tumor necrosis factor (TNF) agents is a rare entity. We reported three cases who developed lupus-like syndrome while receiving infliximab therapy for various reasons. All demonstrated clinical and laboratory findings of SLE. And all them needed treatment. would like emphasize that the risk anti-TNF-alpha-induced should be kept in mind patients anti-TNF any reason.