A5113637010- Photodynamic Therapy Research Studies
- Nanoplatforms for cancer theranostics
- Porphyrin and Phthalocyanine Chemistry
- Cancer Research and Treatments
- Mycobacterium research and diagnosis
- Helicobacter pylori-related gastroenterology studies
- Tuberculosis Research and Epidemiology
- Cancer, Hypoxia, and Metabolism
- Sports injuries and prevention
- Sport Psychology and Performance
- Microbial Metabolites in Food Biotechnology
- Sports Performance and Training
- Influenza Virus Research Studies
- Porphyrin Metabolism and Disorders
- Erythropoietin and Anemia Treatment
- Hormonal and reproductive studies
- Biochemical and Molecular Research
- Escherichia coli research studies
- Animal Disease Management and Epidemiology
- Respiratory viral infections research
- Science, Research, and Medicine
- Microbial Inactivation Methods
- Motivation and Self-Concept in Sports
- Salmonella and Campylobacter epidemiology
- Biosimilars and Bioanalytical Methods
University of Winchester
2021
Wokingham Hospital
2007
National Institute for Biological Standards and Control
2001
University College London
1991-1996
Walton Hospital
1992-1993
Postgraduate School of Molecular Medicine
1993
National Oceanography Centre
1991-1993
Devon History Society
1991-1992
Imperial College London
1992
Abstract Photodynamic therapy (PDT) is often thought to be able effect selective tumour necrosis. This therapeutic selectivity, based on transient diferences in tumour: normal tissue photosensitizer concentration ratios, rarely useful clinically extracranial tumours, although PDT itself may of value by virtue the nature damage produced and healing regeneration. report describes effects pancreas chemically induced pancreatic cancers hamster, where a diferent mechanism necrosis seen....
Abstract— —We have previously reported photodynamic therapy of normal rat colon using aluminium sulphonated phthalocyanine (AlSPc). In that study, the AlSPc used was a mixture phthalocyanines different degrees sulphonation. Phthalocyanines defined sulphonation recently become available and we compared distribution di‐ tetra‐sulphonates (AlS 2 Pc AlS 4 Pc) in wall structures employing both chemical extraction fluorescence photometry charge coupled device imaging system. Also, effects produced...
Highly pathogenic avian influenza A viruses of the H5N1 subtype continue to circulate in poultry, and zoonotic transmissions are reported frequently. Since a pandemic caused by these highly is still feared, there interest development A/H5N1 virus vaccines that can protect humans against infection, preferably after single vaccination with low dose antigen. Here we describe induction humoral cellular immune responses ferrets cell culture-derived whole inactivated vaccine combination novel...
Helicobacter pylori is associated with various gastrointestinal disorders. Lethal photosensitisation was investigated as a possible technique for killing H. which might offer better alternative to antibiotics. The susceptibility of lethal determined by mixing suspensions photosensitisers and plating out on blood agar before irradiation low-power laser light. Five sensitisers were studied further them in tissue-culture plate counting survivors after function exposure time, dye concentration...
We have evaluated an oral vaccine based on Salmonella enteric serovar typhi (S. typhi) Ty2 derivative TSB7 harboring deletion mutations in ssaV (SPI-2) and aroC together with a chromosomally integrated copy of eltB encoding the B subunit enterotoxigenic Escherichia coli heat labile toxin (LT-B) volunteers. Two doses 10(8) or 10(9)CFU were administered to two groups volunteers both well tolerated, no vaccinemia, only transient stool shedding. Immune responses LT-B S. lipopolysaccharide...
BACKGROUND--Photodynamic therapy (PDT) is a technique for producing localised tissue necrosis with light after prior administration of photosensitising drug. There some selectivity uptake photosensitisers in malignant tissue, although this difficult to exploit. Full thickness normal and neoplastic colon heals without perforation because lack effect on collagen, making local cure possibility. The experiments described here aim establish whether these conclusions are also valid bronchial...
Radioprotective agents have been found to protect normal tissues during photodynamic therapy (PDT). We investigated a phosphorylated thiol protectant WR-77913 (W7) with the photosensitizer aluminium sulphonated phthalocyanine (AISPc). compared effects of PDT on and tumour tissue in rat colon, without this protectant. In colon no necrosis was seen sites treated after administration W7. Necrosis mean diameter 4.2 mm those given light exposure. At area similar exposure before protective agent....
The role of a forward player in soccer is to score goals by destabilising defensive systems. act goal scoring open play fast paced with players requiring perceptual ability navigate the environment. purpose this research study was explore scorers’ perceive and adapt environmental threats at different competitive levels. All scored 2022/23 English Premier League, Championship, League 1, 2 divisions were analysed. Four observers recorded proximity defenders scorer moment assist pass finish....
The influence and interaction of perceived experience on athlete development during deliberate practice activities is unknown. current study aimed to explore the developmental experiences high performing athletes practice. Participants were 15 Talented Athlete Scholarship Scheme Dual Career (8 females, 7 males, aged between 17 18 years) enrolled in full-time UK tertiary education. Experiential data was collected through semi-structured interviews thematically analyzed. Ten overarching themes...