Background: Diabetes mellitus, a metabolic disease characterized by high blood glucose levels, has increased dramatically in recent years, prompting the need for more affordable diagnoses and treatments. Objective: This study aimed to conduct brief historical theoretical review on development of insulin. Methods: Scientific technological data have been retrieved analyzed with focus active pharmaceutical ingredient insulin insulin-based medicines. Data from PubMed database available via CAPES...

The paper presents basic concepts on nanotechnology and the use of this in an oil gas research development (R&D) center, Research Development Center Leopoldo Américo Miguez de Mello Petrobras (CENPES).The aim is to present a proposal observatory trends area at CENPES, generate information, such as state art technologies, technological trajectories, movements competitors partners, aspects relating regulations incentives for decision making technology management process.The model consists five...

The use of enzymes in the pulp and paper industry was introduced 1986.However, their has been relatively minor.This prospective study aims at enhancing understanding most important advances regarding this to identify future trends technology.Information gathered from Web Science shows a growing number papers published on topic indicating an increased interest issue.A patents also displayed high documents related technology.Cellulase, xylanase, laccase lipase are that can be used...

Fertilizers are essential inputs for the agribusiness chain—they increase productivity on available arable land and help to avoid changes in use. Currently, Brazil is one of largest consumers fertilizers world but its imports NPK fertilizers, as a percentage total consumption, have risen from 32% 1988 77% 2018. Biofuels relevant transport sector Brazilian government, after Paris Agreement, created National Policy (Renovabio), which has goals raise participation biofuels 28.6% by 2028. Soy,...

Introduction There has been a dramatic global surge in dengue fever (DF) recent years, with projected 100-400 million cases annually and large outbreaks expected every 3-4 years. This concerning scenario is sharp contrast to the very low availability of vaccines meet this spiraling demand, particularly affecting developing countries Latin America Africa. In our study, we aim identify current vaccine development constraints, from technological perspective, based on clinical trials patent...

Global access to clean water and sanitation has been broadly discussed in the context of Sustainable Development Goals adopted by United Nations. In this context, membrane technology increasingly applied with great success wastewater treatment. Considering relevance patent information for understanding current status future trends technologies, filings on treatment period from 2011 2019 were analyzed. This study comprised a global analysis, aimed at determining most general aspects,...

Resumo: A inovação é um elemento fundamental para o desenvolvimento e crescimento, mas constituída por processo demorado de acúmulo conhecimento. Uma das formas acelerar tal meio da transferência tecnologia. Este artigo mapeou as particularidades tecnologia a vacina contra COVID-19, celebrado entre AstraZeneca Instituto Tecnologia em Imunobiológicos (Bio-Manguinhos), Fundação Oswaldo Cruz, bem como reconheceu os seus facilitadores, entraves suas lacunas. Para tanto, foi realizada uma análise...

Investment in nanotechnology is now a given constant by governments, research centers and companies both more developed countries emerging markets. Due to their characteristics, such as high stability, ability enable antigen identification on specific cells the human body controlling release of drugs and, therefore, improving therapies, nanoparticles have been subject patent applications pharmaceutical field. According Organization for Economic Co-operation Development (OCDE), data can be...

Purpose This paper aims to present a methodology for technological foresight and scanning based on S&T knowledge indicators. Design/methodology/approach proposal considers indicators, such as patents indicator (technology), research development (science) competencies (human resources). International databases data‐and text‐mining tool are used build up maps reference tables support decision making. Findings study provides information about the use of using biotechnology in health sector...

This article has the objective to describe and characterize textile sector's technology transfer process, under light of core theoretical concepts, dynamics technological characterization.In addition shows main bottlenecks observed in possible actions for involved actors seek a better execution technologic transfer, thus reducing acquired under-utilization, as well delay on its full use.

This paper identifies the current portfolio of Brazilian Network for Public Production Medicines (RBPPM) and evaluates modernization expansion Official Pharmaceutical Laboratories (OPLs) production capacity in last seven years. Investments about R$ 300 million have been made to expand annual installed from 5 16.6 billion Units 1 (PUs). The work consisted interviews, literature searches queries database Association, National Health Surveillance Agency (ANVISA), Ministry (MS) Science...

The unceasing demand for electronic equipment has led to numerous problems, such as environmental damage and raw material shortages. adoption of circular production chains the precepts economy when designing could minimize these problems by fostering reuse resources without loss quality or value. scientific literature many studies on importance production, but there are no data demonstrate whether information produced is being taken up industry. This study analyzes patent applications...

The last several years have revealed information technology and scientific data to be important allies. However, the most ally is that which can assist in complex task of identifying, collecting treating exponential amount added Web every day XXI century. Moreover, volume this exceeds 2.5 x 1018 new bytes per arrives on at a rapid speed. Thus, it necessary assess veracity these their value decision-making. Although approximately 43% are related health about one million articles published...

Water scarcity is a threat for mankind and its symptoms have been aggravated by several factors such as climate change effects, increase in population accelerated urbanization. Among the alternatives of water supply, desalination has become one most sustainable solutions to provide freshwater. However, process requires high quantities energy use renewable sources can make technology affordable regions characterized fresh-water where supply from electricity not accessible. In this context,...

Population aging and the consequent change in profile of age pyramid are already a reality world over. One undeniable effect this process is significant increase number people with Alzheimer's disease (AD), which most common form dementia, accounting for around 50% - 60% all cases. AD tends to affect their 60 s, becoming progressively more commonplace older groups. It an incurable disease, patients can live many years taking medication on daily basis. This study shows that research into rise...