Levoglucosan could be obtained by biomass pyrolysis and chemically transformed to high-added value compounds becoming a promising platform molecule.

Trametes versicolor 's laccase (Lac TV ) was efficient catalyst in HMF oxidation to FDCA. Its use an enzymatic and photocatalytic cascade process permitted a 40-fold increase FDCA productivity compared traditional batch systems.

Background: Diabetes mellitus, a metabolic disease characterized by high blood glucose levels, has increased dramatically in recent years, prompting the need for more affordable diagnoses and treatments. Objective: This study aimed to conduct brief historical theoretical review on development of insulin. Methods: Scientific technological data have been retrieved analyzed with focus active pharmaceutical ingredient insulin insulin-based medicines. Data from PubMed database available via CAPES...

A wide range of agro-industrial waste has been generated due to higher demands for food and energy. New protocols its valorization are urgent strategies sustainable development. In this work, residual babassu mesocarp, a native plant from the north Brazil, was used as matrix producing lipases through solid-state fermentation (SSF) by actinobacterial strains. Initially, 121 strains were screened rhodamine B tributyrin methods, where strain Streptomyces spp. AM9-01 most promising. It submitted...

Continuous-flow biocatalysis using immobilized lipases and transaminases in order to synthesize chiral alcohols amines respectively.

Biodegradable, biocompatible and nontoxic nonionic surfactants are widely used in food, pharmaceutical industrial applications being commonly produced based on alkaline-catalyzed chemical glycerolysis of natural oil fats at high temperatures elevated pressure under nitrogen atmosphere. In this work we have optimized a biocatalytic continuous flow process with packed bed reactor for the esterification reaction between (R,S)-1,2-isopropylidene glycerol stearic acid using response surface...

Several value-added products can be produced from glycerol and among these carbonate (GC) has received much attention in recent years because of its physical properties wide application the chemical, pharmaceutical food industries.

Among several value-added products from glycerol, glyceryl carbonate (GC) has gained prominence during the recent years because of its attractive physicochemical properties and wide range industrial applications. As a continuation our efforts on GC production under environmentally benign conditions, in this work, we have applied combination two new biocatalysts containing lipases porcine pancreas Candida antarctica immobilized epoxy resins for via an integrated reaction between...

Zika virus (ZIKV) was first detected in Brazil 2015 and then rapidly spread to more than 80 countries Africa, Asia the Americas. ZIKV infection correlated with severe congenital malformations newborns from infected mothers, as well Guillain-Barré syndrome adults. Although number of people has declined affected lately, development a vaccine for is great importance avoid future resurgence endemic areas or currently non-endemic regions. Among many different platforms under study, virus-like...

Furfural (FF) is a strategic product for the development of highly valued chemicals from biomass. The oxidation FF, furoic acid (FA), an important precursor synthesis green esters, such as methyl furoate. Taking into account issues with direct furfural oxidation, derivatives, alkyl furoates, can be easily prepared via oxidative esterification. Here, Au nanoparticles that were immobilized on alkaline-earth metal oxide supports studied esterification while using alcohol both reactant and...

From the fusion of bio- and chemocatalysts, immobilized in innovative materials, a new family catalysts is emerging: multi-catalytic hybrid materials (MCHMs). It offers atom energy savings and, above all, prospects chemical synthesis.

In this work, solid-state fermentation (SSF) was applied to babassu mesocarp (BM) for the low-cost bioproduction of natural aroma compounds having Trichoderma harzianum (IOC 4042) and Geotrichum candidum (CCT 1205) as microbial agents. Fermentation carried out using in natura (IN-BM) defatted through soxhlet extraction (DEF-BM) support, impregnated with hydration solutions three seven salts. The produced were analyzed solid phase microextraction (SPME) gas chromatography coupled a mass...

Silica immobilized lipases have been prepared and utilized in the valorization of fatty acid-derived food waste streams under continuous flow conditions. Findings demonstrate that better conversions could be obtained when compared with commercially available enzymes.

Abstract BACKGROUND In this work, lipase B from Candida antarctica (CaLB) was immobilized on Purolite® ECR8205F, ECR8214F and Immobead® IB150 P epoxy resins with no modification to their surfaces. Biocatalysts were evaluated for thermal stability applied in reactions of hydrolysis, esterification the synthesis glyceryl carbonate by transesterification dimethyl‐carbonate both glycerol Macauba oil as well dynamic kinetic resolution α‐methylbenzylamine, all them compared commercial Novozyme...

As a consequence of intense industrialization in the last few decades, amount agro-industrial wastes has increasing, where new forms valorization are crucial. In this work, five residual biomasses from Maranhão (Brazil) were investigated as supports for immobilization lipase Thermomyces lanuginosus (TLL). The biocatalysts BM-TLL (babaçu mesocarp) and RH-TLL (rice husk) showed efficiencies >98% hydrolytic activities 5.331 U g−1 4.608 g−1, respectively, against 142 by Lipozyme® TL IM. High...

The high demand for food and energy imposed by the increased life expectancy of population has driven agricultural activity, which is reflected in larger quantities agro-industrial waste generated, requires new forms use. Brazil greatest biodiversity world, where corn one main genres, over 40% generated from cobs without an efficient destination. With aim valorization these residues, we proposed to study immobilization laccase Aspergillus spp. (LAsp) residual cob its application degradation...

During recent decades, the use of enzymes or chemoenzymatic cascades for organic chemistry has gained much importance in fundamental and industrial research. Moreover, several enzymatic reactions have also served green sustainable manufacturing processes especially fine chemicals, pharmaceutical, flavor/fragrance industries. Unfortunately, only a few been applied at scale because low stabilities along with problematic their recovery reuse. Immobilization co-immobilization offer an ideal...

The present paper describes the phytochemical and anti-staphylococcal activity investigation of dichloromethane extract Brazilian plant Zizyphus joazeiro Mart. purification steps were guided by bioassays against 17 bacterial strains clinical sources, including methicillin-resistant (MRSA) ‐sensitive (MSSA) Staphylococcus aureus as well MRSA (ATCC 33591) MSSA 29213) reference strains. One more active fractions is comprised three lupane-type triterpenes, methylbetulinate (1) known betulinic...