A5000981231- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Innovations in Medical Education
- Spinal Fractures and Fixation Techniques
- Scoliosis diagnosis and treatment
- Social Media in Health Education
- Problem and Project Based Learning
- Medical Imaging and Analysis
- Interprofessional Education and Collaboration
- Bone health and osteoporosis research
- Innovations in Educational Methods
- Muscle Physiology and Disorders
- Musculoskeletal Disorders and Rehabilitation
- Cervical and Thoracic Myelopathy
- Myofascial pain diagnosis and treatment
- Mitochondrial Function and Pathology
- Dental Research and COVID-19
- Diversity and Career in Medicine
- Simulation-Based Education in Healthcare
- Radiology practices and education
- Healthcare Systems and Technology
- Entomological Studies and Ecology
- Bone fractures and treatments
- Muscle metabolism and nutrition
- Body Composition Measurement Techniques
Helios Klinikum Emil von Behring
2019
Charité - Universitätsmedizin Berlin
2007-2016
Berlin Institute of Health at Charité - Universitätsmedizin Berlin
2013-2016
Berlin-Brandenburger Centrum für Regenerative Therapien
2011-2013
Wellcome Trust
2011-2012
National Institutes of Health
2011-2012
Howard Hughes Medical Institute
2011-2012
Study Design Prospective cohort study comparing evaluations of single-level anterior lumbar interbody fusion (ALIF) versus anteroposterior (APLF). Objective To clinically and radiologically compare the outcome after angle-stable, locked, stand-alone ALIF with that obtained APLF, in cases degenerative disc disease (DDD). Summary Background Data Fusion rates have been reported to be highest transpedicular fixation. However, fixation is linked significant damage paravertebral muscles, screw...
Study Design: Pilot study. Objective: To develop and validate the feasibility accuracy of a newly designed navigational spinal instrument guiding tool for patient-matched thoracic lumbar pedicle screw placement in patients with severe scoliosis, to identify intraoperative challenges that may be relevant. Summary Background Data: Pedicle is challenging severely rotated scoliotic spine small diameters asymmetrical shape pedicles vertebrae. Patient-specific drill/positioning guides preplanned...
While e-learning is enjoying increasing popularity as adjunct in modern teaching, studies on this topic should shift from mere evaluation of students' satisfaction towards assessing its benefits enhancement knowledge and skills. This pilot study aimed to detect the teaching effects a blended learning program students orthopedics traumatology context problem-based environment.The project NESTOR (network for orthopedics) was offered course. Participants completed written tests before directly...
OBJECT To date, it remains unclear whether the preservation of segmental motion by total disc replacement (TDR) or restriction stand-alone anterior lumbar interbody fusion (ALIF) have an influence on postoperative degeneration posterior paraspinal muscles associated clinical results. Therefore, purpose present prospective randomized study was to evaluate parameters and 3D quantitative radiological changes in spine surgically treated segments superior adjacent after ALIF TDR. METHODS A 50...
Single-center prospective study.Clinical and radiological long-term evaluation of the effects transpedicular dynamic stabilization after sequestrectomy.Short- mid-term investigations have shown that additional is appropriate to prevent progression initial segment degeneration sequestrectomy associated with superior clinical outcome compared alone. Long-term data are missing.Eighty-four patients symptomatic disc herniation osteochondrosis (Modic = I°) lumbar spine underwent sequestrectomy....
Knowledge about factors leading to failure of posterior dynamic stabilization implants is essential design future and establish surgical indications. Therefore, we analyzed an implant for single-level or hybrid configuration (adjacent spondylodesis), which was recalled due high rates.We asked: (1) Were postoperative radiographic changes linked failure? (2) parameters different between the two configurations? And (3) related inferior clinical scores?The used in 18 patients with lumbar spinal...
Retrospective analysis of clinical and radiologic data a prospective cohort study.To research the differences after lumbar total disk replacement (TDR) with respect to preoperative global adaptation at local sagittal profile (SP) spine.It was suggested that facet loads degeneration are dependent on epidemiologically defined types SP. Moreover, success TDR related segmental joint loads. The influences SP or changes outcome remain unclear.Fifty-two patients included in study regarding...
To evaluate training induced metabolic changes noninvasively with (31)P magnetic resonance spectroscopy ((31)P-MRS) for measuring muscle fibre type adaptation.Eleven volunteers underwent a 24-week training, consisting of speed-strength, endurance, and detraining (each 8 weeks). Prior to following each period, needle biopsies (31)P-MRS the resting gastrocnemius were performed. Fibre distribution was analyzed histologically tested correlation ratios high energy phosphates ([PCr]/[P(i)],...
The objective of this study is to assess the clinical performance a novel ultrasound bidirectional axial transmission (BDAT) prototype. speed sound first arriving signal (V <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">FAS</inf> ) was measured in radius and tibia 58 postmenopausal females. An optimized V measurement protocol introduced order reduce time increase robustness particular for patients with pronounced body mass index (BMI)....
The objective of this study is to assess the clinical performance a novel bi-directional axial transmission (BDAT) ultrasound prototype. speed sound first arriving signal (V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">FAS</sub> ) was measured at radius (single site) and tibia (two sites) 51 post-menopausal females. An optimized V measurement protocol introduced reduce time (from 30 10 minutes) by maintaining robustness former method....