A5001670264- COVID-19 epidemiological studies
- Fecal contamination and water quality
- Salmonella and Campylobacter epidemiology
- Bacterial Identification and Susceptibility Testing
- Antibiotic Resistance in Bacteria
- Viral Infections and Outbreaks Research
- Reproductive tract infections research
- Antibiotic Use and Resistance
- Antibiotics Pharmacokinetics and Efficacy
- Pneumonia and Respiratory Infections
- Food Safety and Hygiene
- COVID-19 Pandemic Impacts
- Vaccine Coverage and Hesitancy
- Streptococcal Infections and Treatments
- Antimicrobial Resistance in Staphylococcus
- COVID-19 Clinical Research Studies
- Child Nutrition and Water Access
- Wastewater Treatment and Reuse
- Bacterial Infections and Vaccines
- SARS-CoV-2 and COVID-19 Research
- Parasitic infections in humans and animals
- Infective Endocarditis Diagnosis and Management
- Surgical site infection prevention
- COVID-19 diagnosis using AI
- Pharmaceutical and Antibiotic Environmental Impacts
Public Health Agency of Canada
2014-2024
Université de Montréal
1994-2024
University of Ottawa
2022
Children's Hospital of Eastern Ontario
2022
Dalhousie University
2022
University of Manitoba
2022
Ottawa Hospital
2022
Ottawa Hospital Research Institute
2022
Cegep de Saint Hyacinthe
2017
Hôpital Saint-Luc
1978-1997
Background: Severe acute respiratory syndrome virus 2 (SARS-CoV-2), likely a bat-origin coronavirus, spilled over from wildlife to humans in China late 2019, manifesting as disease.Coronavirus disease 2019 (COVID-19) spread initially within and then globally, resulting pandemic.Objective: This article describes predictive modelling of COVID-19 general, efforts the Public Health Agency Canada model effects non-pharmaceutical interventions (NPIs) on transmission SARS-CoV-2 Canadian population...
Continual efforts to eliminate community transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) will be needed prevent additional waves infection. We explored the impact nonpharmaceutical interventions on projected SARS-CoV-2 in Canada.
This study illustrates what may have happened, in terms of coronavirus disease 2019 (COVID-19) infections, hospitalizations and deaths Canada, had public health measures not been used to control the COVID-19 epidemic, restrictions lifted with low levels vaccination, or no Canadian population. The timeline epidemic interventions are reviewed. Comparisons against outcomes other countries counterfactual modelling illustrate relative success Canada. Together, these observations show that without...
INTRODUCTION: Human exposure to antimicrobial‐resistant bacteria may result in the transfer of resistance commensal or pathogenic microbes present gastrointestinal tract, which lead severe health consequences and difficulties treatment future bacterial infections. It was hypothesized that recreational waters from beaches represent a source Escherichia coli for people engaging water activities. OBJECTIVE: To describe occurrence E southern Quebec. METHODS: Sampling occurred over two summers;...
Salmonella infections remain an important public health issue in Canada and worldwide. Although the majority of cases are self-limiting, some will lead to severe symptoms occasionally invasive infections, especially vulnerable populations such as seniors. This study was performed assess temporal trends seniors over 15 years (2014-2028) possible impact demographic shift on national incidence; taking into account other age groups. The numbers reported (60 over) eight provinces territories for...
Background: Shutdowns are enacted when alternative public health measures insufficient to control the epidemic and population is largely susceptible. An age-stratified agent-based model was developed explore impact of shutdowns SARS-CoV-2 transmission in Canada under assumption that current efforts remains absence a vaccine. Methods: We estimated levels interventions generate baseline scenario from 7 February September 2020. Four aspects were explored scenarios ran 8 2020 January 2022, these...
A retrospective study was conducted to assess the relationships between clindamycin resistance in members of Bacteroides fragilis group, previous antimicrobial therapy, and context for development infection, whether community or during hospitalization. Eighty-five clindamycin-resistant clinical strains (one isolate per patient) isolated from January 1988 October 1994 were matched one) with clindamycin-susceptible isolates recovered same period, charts patients whom reviewed retrospectively....
A total of 579 clinical isolates the Bacteroides fragilis group collected from three Canadian hospitals were tested for susceptibility to five antimicrobial agents by using an agar dilution method. During 4-year survey, intra-abdominal infections following sites: abdominal abscesses (48%), peritoneal fluid (39%), blood (10%), and bile (3%). B. was most prevalent species (35.4%), followed thetaiotaomicron (19.2%), ovatus (15.9%), vulgatus (11%). No metronidazole- or imipenem-resistant strains...
One hundred and eighty-one anaerobic bacteria recovered from infections were tested by agar dilution technique against 10 antimicrobial agents. The MIC read after 24 h of incubation shows that metronidazole, chloramphenicol clindamycin appear to be the more frequently effective drugs B. fragilis. Among cephalosporins tested, cefoxitin was most active followed cefamandole cefazolin. results compared other studies indicated a decreased activity penicillin G, carbenicillin, tetracycline.
Estimating rates of disease importation by travellers is a key activity to assess both the risk country from an infectious emerging elsewhere in world and effectiveness border measures. We describe model used estimate number infected with SARS-CoV-2 into Canadian airports 2021, impact pre-departure testing requirements on risk.
Echinococcus spp. is an emerging zoonotic parasite of high concern. In Canada, increase in the number human and animal cases diagnosed has been reported, but information regarding parasite's distribution wildlife reservoir remains limited. A cross-sectional study was conducted to estimate prevalence wild canids infected with multilocularis areas surrounding populated zones Québec (Canada); investigate presence at higher risk infection; evaluate potential factors as a secondary objective,...
SUMMARY Salmonella is one of the most prevalent bacteria associated with enteric illness in Canada and seniors are considered a vulnerable population more likely to develop severe illness. In coming decades, hospitalizations deaths could represent challenge due an aging Canada. The numbers non-typhoidal (NT) -related from Canadian Hospitalization Morbidity Database were analysed for period 10 years seniors. rate calculations descriptive analyses performed on variables burden hospitalization...
Public health risks related to the microbial contamination of recreational waters are increased by global environmental change. Intensification agriculture, urban sprawl, and climate change some changes which can lead favorable conditions for emergence waterborne diseases. Earth observation (EO) images have several advantages characterization monitoring determinants that could be associated with risk in vast territories like Canada. There a large number EO systems characterized different...
Public health measures applied exclusively within vulnerable populations have been suggested as an alternative to community-wide interventions mitigate SARS-CoV-2 transmission. With the population demography and healthcare capacity of Canada example, a stochastic age-stratified agent-based model was used explore progression COVID-19 epidemic under three intervention scenarios (infection-preventing vaccination, illness-preventing vaccination shielding) in individuals above age thresholds...
The serogroup/serotypes (SGTs) and antimicrobial susceptibilities to 10 agents of 110 clinical strains Streptococcus pneumoniae were determined. Strains intermediately resistant or highly penicillin G (80 110) belonged predominantly SGTs 23 (45.0%), 19 (13.7%), 6 (10.0%), 9 (6.2%), 14 (3.7%). MICs all cephalosporins, tetracycline, trimethoprim-sulfamethoxazole, chloramphenicol increased along with the G. However, erythromycin resistance clindamycin observed more frequently among...
A collection of 120 oxacillin-susceptible and oxacillin-resistant coagulase-negative staphylococci (CNS) from six tertiary care hospital laboratories were tested by agar disk diffusion, three microdilution broth systems (Sensititre, Dynatech, Alpkem), the Vitek AutoMicrobic system for comparison with reference dilution results. The antimicrobial agents oxacillin, cefazolin, cefotaxime, cefuroxime, cefamandole, fusidic acid, rifampin, vancomycin. Incubation was at 30 or 35 degrees C 24, 48,...
Summary Exposure to microorganisms resistant antimicrobials may constitute a health risk human populations. It is believed that one route of exposure occurs when people engage in recreational activities water contaminated with these microorganisms. The main objective this study was explore population‐level and environmental determinants specifically associated the presence antimicrobial (AMR) generic Escherichia coli isolated from waters sampled beaches located southern Quebec, Canada. Water...
Recreational waters are associated with a higher risk of disease for people engaged in activities that bring them into contact these waters. The primary cause contamination recreational is fecal microorganisms, which may originate from various sources and involve several modulating factors, making it complex public health en- vironmental issue. Monitoring water quality should include two key components: Microbial testing monitoring environmental determinants risks contamination. Conducting...
Diverse fecal and nonfecal bacterial contamination nutrient sources (e.g. agriculture, human activities wildlife) represent a considerable non-point source load entering natural recreational waters which may adversely affect water quality. Monitoring of microbial quality is most often based mainly on testing set microbiological indicators. The cost labour involved in numerous samples be significant when large number sites must monitored repetitively over time. In addition to testing, ongoing...