A5063919212- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Atherosclerosis and Cardiovascular Diseases
- Mechanical Circulatory Support Devices
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Disease and Adiposity
- Cardiovascular Function and Risk Factors
- Lipoproteins and Cardiovascular Health
- Radiation Dose and Imaging
- Cardiac Valve Diseases and Treatments
- Vascular Procedures and Complications
- Cardiac Structural Anomalies and Repair
- Cardiac Arrest and Resuscitation
- Aortic aneurysm repair treatments
- Diabetes Management and Research
- Acute Ischemic Stroke Management
- Peripheral Artery Disease Management
- Venous Thromboembolism Diagnosis and Management
- Viral Infections and Immunology Research
- Aortic Disease and Treatment Approaches
- Advanced MRI Techniques and Applications
- Infective Endocarditis Diagnosis and Management
- Amoebic Infections and Treatments
- Coronary Artery Anomalies
National Cerebral and Cardiovascular Center
2016-2025
Kumamoto University
2002-2023
Kyoto University
2023
Vanderbilt University Medical Center
2023
Ted Rogers Centre for Heart Research
2023
University Health Network
2023
Tohoku University
2022
Percutaneous veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is utilized for patients with cardiogenic shock or cardiac arrest. However, the procedure protocol weaning from VA-ECMO has not been well established. The present study aimed to determine usefulness of echocardiographic and pulmonary artery catheter parameters predicting successful in refractory shock.We retrospectively studied 50 who were hospitalized supported by >48 h between January 2013 March 2017. Patients...
Background The role of cyclic guanosine 3′,5′-monophosphate (cGMP) after acute myocardial infarction (AMI) is not well understood despite its significance as a second messenger natriuretic peptides (NPs) in cardiovascular disease. We investigated the association between NP-cGMP cascade and left ventricular reverse remodelling (LVRR) anterior AMI. Methods 67 patients with their first AMI (median age, 64 years; male, 76%) underwent prospective evaluation plasma concentrations molecular forms...
Background Acute myocardial infarction (AMI) infrequently occurs after acute stroke. The Heart-brain team approach has a potential to appropriately manage this poststroke cardiovascular complication. However, clinical outcomes of AMI complicating stroke (AMI-CAS) with the heart-brain have not been characterized. current study investigated in patients AMI-CAS managed by team. Methods and Results We retrospectively analyzed 2390 at our institute (January 1, 2007-September 30, 2020). was...
Randomized clinical trials have demonstrated the ability of glucagon-like peptide-1 analogues (GLP-1RAs) to reduce atherosclerotic cardiovascular disease events in patients with type 2 diabetes (T2D). How GLP-1RAs modulate diabetic atherosclerosis remains be determined yet.
Background: Intravascular imaging has shown better response of coronary atheroma to statin-mediated lowering low-density lipoprotein cholesterol in women. However, its detailed mechanism remains be determined yet. Modifiability under lipid-lowering therapies is partly driven by lipidic plaque component. Given a smaller volume women, features including their density may differ between sex. Therefore, the current study sought characterize sex-related differences plaque. Methods: We analyzed...
Abstract There were no data comparing the in-hospital outcomes after transcatheter aortic valve implantation (TAVI) with those surgical replacement (SAVR) in Japan. Among consecutive patients severe AS between April 2018 and December 2020 CURRENT Registry-2, we identified 1714 who underwent (TAVI group: 1134 patients, SAVR 580 patients). Patients TAVI group much older (84.4 versus 73.6 years, P < 0.001) more often had comorbidities than group. In-hospital death rate was numerically lower...
There is scarce data evaluating the current practice pattern and clinical outcomes for patients with severe aortic stenosis (AS), including both those who underwent surgical valve replacement (SAVR) or transcatheter implantation (TAVI) were managed conservatively in TAVI era.
Continuous glucose monitoring (CGM) improves glycemic fluctuation and reduces hypoglycemic risk. Whether CGM-guided control favorably modulates coronary atherosclerosis in patients with type 2 diabetes (T2DM) remains unknown.The OPTIMAL trial was a prospective, randomized, single-center which 94 T2DM CAD were randomized to CGM- or HbA1c-guided for 48 weeks (jRCT1052180152). The primary endpoint the nominal change total atheroma volume (TAV) measured by serial IVUS. secondary efficacy measure...
A sufficient condition is given for the existence of an unknown input observer under assumption observability in sense Rosenbrock. The conditions are easily checked system's parameters. result applied to state estimation a descriptor system with unmeasurable disturbances.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Connective tissue disorders sometimes involve cardiovascular systems. This report describes the case of a middle-aged man with mitral regurgitation and heart failure. He had distinctive features mucopolysaccharidosis type (MPS) III, but no gene mutations that were known to be associated MPS. Meanwhile, he COL1A2 mutation is osteogenesis imperfecta (OI), some compatible OI. The patient might have rare connective disorder characteristics MPS III OI, which was initially detected as result...
Background: While internal mammary artery (IMA) has become a major conduit of coronary bypass graft (CABG) surgery, subclavian stenosis (SAS) could cause subsequent events due to ischemia myocardial territory supplied by IMA. Clinical characteristics and cardiovascular outcomes SAS-related IMA failure (SAS-IMAF) remain be fully determined yet. Therefore, the current study was designed characterize SAS-IMAF in patients receiving CABG with Methods: This is retrospective observational which...
BACKGROUND: Cardiovascular events still occur at intermediate stenosis with fractional flow reserve (FFR) ≥0.81, underscoring the additional measure to evaluate this residual risk. A reduction in distal coronary artery pressure/aortic pressure (Pd/Pa) from baseline hyperemia (ie, change Pd/Pa) reflects lipidic burden within vessel walls. We hypothesized that physiological might stratify risk of future cardiac deferrable lesions. METHODS: Lesion- (899 lesions) and patient-based deferred...
Background: Natriuretic peptides and their second messenger, cyclic guanosine monophosphate (cGMP), play a critical role in the pathogenesis of cardiovascular diseases by inhibiting renin-aldosterone system, cardiac hypertrophy, fibrosis. Recently developed chemiluminescent enzyme immunoassays for proBNP have enabled estimation mature BNP (emBNP) calculating difference between total proBNP. Research Questions: The cGMP left ventricular remodeling after acute myocardial infarction (AMI)...
Objective: In the REDUCE-IT trial, high doses of eicosapentaenoic acid (EPA) demonstrated a significant absolute risk reduction in its primary endpoint among patients with hypertriglyceridemia and cardiovascular risk. However, mechanism action long-chain N-3 polyunsaturated fatty acids, EPA docosahexaenoic (DHA), has not been fully investigated. The AQUAMARINE EPA/DHA study aims to investigate effect on high-risk coronary plaques after 12 months, using cardiac magnetic resonance imaging...
The walking motion is realized as a result of cooperation the motions in frontal plane and sagittal plane. In this paper, designing method hierarchical control system for biped locomotion robot presented. system, trajectory planning pattern executed at upper level servo planned lower level. designed part. part, it considered to follow that so stable realized.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>