A5077235526- Cardiovascular Function and Risk Factors
- Chronic Myeloid Leukemia Treatments
- Acute Myeloid Leukemia Research
- Cardiovascular Disease and Adiposity
- Cardiac Imaging and Diagnostics
- Cardiovascular Effects of Exercise
- Heart Failure Treatment and Management
- Cardiovascular and exercise physiology
- Pharmaceutical and Antibiotic Environmental Impacts
- Cardiomyopathy and Myosin Studies
- Cardiac Arrhythmias and Treatments
- Chronic Lymphocytic Leukemia Research
- Microbial bioremediation and biosurfactants
- Cardiac Valve Diseases and Treatments
- Acute Lymphoblastic Leukemia research
- Potassium and Related Disorders
- Effects and risks of endocrine disrupting chemicals
- Synthesis and biological activity
- Environmental Chemistry and Analysis
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Hematological disorders and diagnostics
- Cardiac electrophysiology and arrhythmias
- Cancer Treatment and Pharmacology
- Atrial Fibrillation Management and Outcomes
- Oxidative Organic Chemistry Reactions
Osaka Metropolitan University
2022-2025
Metropolitan University
2025
Tokyo Metropolitan University
2022-2025
Keio University
2024
Advanced Institute of Industrial Technology
2024
Nagoya University Hospital
2020-2023
Osaka City University
2008-2022
Gifu Pharmaceutical University
2019-2022
Osaka University
2022
University of Tsukuba
2021
We hypothesized that exhaled acetone concentration (EAC), reflecting altered blood ketone body metabolism and increased exhaust because of pulmonary congestion in heart failure (HF), would correlate with hemodynamic parameters patients non-ischemic chronic HF.We prospectively enrolled 102 HF New York Heart Association (NYHA) class I-III. Exhaled breath was collected after an overnight fast. Echocardiography cardiac catheterization were performed all patients. also 17 control without HF. EAC...
The synthesis of cis-β-amidevinyl benziodoxolones from the ethynyl benziodoxolone-chloroform complex and sulfonamides is reported. Evidence indicates that highly reactive unsubstituted benziodoxolone undergoes Michael addition sulfonamides, including sterically demanding acyclic amino acid derivatives. selectively deuterated investigation ethynyl-λ3-iodane reactivity are also described.
Background: There are few data verifying the utility of CHADS-P2A2RC score in comparison with CHADS2 for estimating net adverse clinical events (NACE) real-world settings. Methods: We performed analysis a total 3,985 chronic coronary syndrome (CCS) patients without atrial fibrillation (AF) who underwent percutaneous intervention (PCI) between April 2013 and March 2019 whom information was obtained from CLIDAS (Clinical Deep Data Accumulation System)-PCI database. The primary endpoint NACE...
Hospital-associated disability (HAD), characterized by a worsening of activities daily living and physical function following hospitalization, is common complication in older adults during the course acute care hospitalization. HAD significant concern affecting undergoing transcatheter aortic valve implantation (TAVI). This retrospective study investigated 243 consecutive patients who underwent elective transfemoral TAVI between January 2016 April 2022. was defined as decrease at least 1...
The Japanese Hypertrophic Cardiomyopathy Registry Study was designed to provide comprehensive, real-world insights into the clinical characteristics and management of hypertrophic cardiomyopathy (HCM) in Japan. This multicentre, prospective study enrolled consecutive patients with HCM from 24 referral hospitals across Japan starting 2016. baseline 1485 by December 2019 are presented this analysis. median ages at registration diagnosis were 69 60 years, respectively, men accounting for 54%...
Abstract The dechlorination and mineralization of pentachlorophenol (PCP) was investigated by simultaneously or sequentially combining two different anaerobic microbial populations, a PCP‐dechlorinating culture capable the reductive PCP to phenol phenol‐ degrading cultures able mineralize under sulfate‐ iron‐reducing conditions. In combined mixture, (about 35 µM) mostly dechlorinated after incubation for 17 days sulfate‐reducing conditions 22 Thereafter, complete removal occurred within 40...
To elucidate the role of a proteasome-dependent proteolytic pathway in pathogenesis acute renal failure (ARF), we examined effect selective proteasome inhibitor, lactacystin, on ARF induced by ischemia/reperfusion. Ischemic was clamping left artery and vein for 45 min followed reperfusion, 2 weeks after contralateral nephrectomy. Renal function untreated rats markedly decreased at 24 h reperfusion. Intraperitoneal injection lactacystin dose 0.1 mg/kg before occlusion tended to attenuate...
This paper reports the characterization of biodegradation intermediates octylphenol octaethoxylate (OP8EO) by means matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). The test study was carried out in a pure culture (Pseudomonas putida S-5) under aerobic conditions using OP8EO as sole carbon source and 18O-labeled water an incubation medium. In MALDI-MS spectra biodegraded samples, series OPnEO molecules with n = 2−8 EO units their corresponding carboxylic acid...
Limited data exist regarding association between physical performance and in-hospital falls. This study was performed to investigate the falls in a high-risk population.
As a complication of atopic dermatitis (AD), the incidence hypoproteinemia is increasing among infants with severe AD in Japan. It can be life-threatening condition owing to hypovolemic shock as result and vascular infarction thrombocythemia. However, pathophysiology this remains unclear. The objectives present study were two-fold. first objective was determine main route protein loss, i.e. through damaged skin or gastrointestinal tract, insufficient food intake. second identify whether...
The aerobic aquatic metabolism of flumioxazin was studied in two water-sediment systems under illumination and darkness to investigate its degradation profiles. (14)C-Flumioxazin separately labeled at the 1- 2-positions tetrahydrophthalimide moiety or uniformly phenyl ring applied a overlying water rate equivalent 600 g ai/ha by assuming uniform distribution layer depth 100 cm. Flumioxazin rapidly degraded 20 °C waters irrespective irradiation with half-lives 0.1-0.4 day. Both various modes...
Abstract Aims Given the various effects of sacubitril/valsartan in heart failure, a deeper understanding atrial natriuretic peptide (ANP) actions is warranted. Natriuresis fundamental action ANP acute failure (AHF), whereas diuretic effect different each patient according to diversity renal response ANP, which affected by baseline plasma status and deficiency circulating ANP. Meanwhile, associations between other neuroendocrine hormones are unclear. This study investigated impact pivotal on...