- Long-Term Effects of COVID-19
- Peripheral Neuropathies and Disorders
- Parkinson's Disease Mechanisms and Treatments
- Bacterial Infections and Vaccines
- Neurological disorders and treatments
- Multiple Sclerosis Research Studies
- Acute Ischemic Stroke Management
- Infectious Diseases and Tuberculosis
- Health Systems, Economic Evaluations, Quality of Life
- Pneumocystis jirovecii pneumonia detection and treatment
- Tuberculosis Research and Epidemiology
- Autism Spectrum Disorder Research
- Public Health and Social Inequalities
- Salivary Gland Disorders and Functions
- Genetic Neurodegenerative Diseases
- Herpesvirus Infections and Treatments
- HIV Research and Treatment
- Animal Disease Management and Epidemiology
- Hereditary Neurological Disorders
- T-cell and Retrovirus Studies
- Mosquito-borne diseases and control
- Hallucinations in medical conditions
- Vasculitis and related conditions
- Psychological Treatments and Disorders
- Protein Tyrosine Phosphatases
Daniel Alcides Carrión National University
2016-2025
National University of San Marcos
2008-2021
Federico Villarreal National University
2020
Fogarty International Center
2016-2018
National Institutes of Health
2016-2018
University of Washington
2018
United States Naval Medical Research Unit SOUTH
2012-2013
To evaluate the mortality in hospitalized patients with tuberculous meningitis and describe factors associated an increased risk of mortality. Retrospective study between 2006 2015 Peru performing a generalized linear regression to identify predictive in-hospital Of 263 patients, median age was 35 years, 72.6% were men, 38% positive for HIV upon admission, 24% had prior TB infections 2.3% MDR-TB infections. In-hospital 30.4% all final diagnosis TBM. When multivariable analysis applied,...
Background Meningitis caused by Mycobacterium tuberculosis is a major cause of morbidity and mortality worldwide. We evaluated the performance cerebrospinal fluid (CSF) testing with GeneXpert MTB/RIF assay versus traditional approaches for diagnosing meningitis (TBM). Methods Patients were adults (n = 37) presenting suspected TBM to Hospital Nacional Dos de Mayo, Lima, Peru, during 12 months until 1st January 2015. Each participant had single CSF specimen that was divided into aliquots...
Objective: Despite significant progress in understanding the factors influencing cognitive function Parkinson's disease (PD), there is a notable gap data representation for Latinx population. This study aims to evaluate contributors and disparities performance among patients with PD. Methods: A retrospective analysis was conducted based on cross-sectional encompassing demographic, environmental, motor, non-motor characteristics from Latin American Research Consortium Genetics of PD...
Age and sex are known risk factors for Parkinson's Disease (PD), but it remains controversial if there differences in the diagnosis latency. The objective of this study was to examine these Latin America. American Research Consortium on Genetics PD (LARGE-PD) includes patients from countries across America who were diagnosed using UK Brain Bank criteria. Ages at onset (AAO; N = 2,792), (AAD; 1,416), calculated latency (N 1,416) extracted LARGE-PD database compared both males females overall,...
Background In an earlier study, we detected association between human T-cell lymphotropic virus (HTLV) infection and cervical papillomavirus (HPV) in indigenous Amazonian Peruvian women of the Shipibo-Konibo ethnic group. As both HTLV HPV can be transmitted sexually, now report a population-based study examining prevalence risk factors for HTLV-1 HTLV-2 this population. Methods Between July December 2010, conducted comprehensive screening among 15 to 39 years age living two communities...
A 59-year-old man with a history of fever, unsteadiness, hemiparesis, motor aphasia and consciousness disturbance was hospitalized for Streptococcus equi subsp. zooepidemicus meningitis. He denied contact farm animals, but had practice consuming unpasteurized goats' cheese from an uncertain source.
<b><i>Background:</i></b> The COVID-19 pandemic has had a great impact on cognitive health in Latin American older adults, increasing the risk of impairment and dementia. Our objective was to analyze prevalence dementia associated factors adults during SARS-CoV-2 pandemic. <b><i>Methods:</i></b> A multicentric first phase cross-sectional observational study conducted Five thousand two hundred forty-five over 60 years age were studied 10...
Disease burden indicators assess the impact of disease on a population. They integrate mortality and disability in single indicator. This allows setting priorities for health services focusing resources.To analyze neurological diseases Peru from 1990-2015.A descriptive study that used epidemiological data published by Institute Health Metrics Evaluation Global Burden Diseases 1990 to 2015. was measured using disability-adjusted life years (DALY) their corresponding 95% uncertainty intervals...
Herpes simplex virus (HSV) is one of the most commonly identified infectious aetiologies encephalitis in North America and Europe. The epidemiology beyond these regions, however, poorly defined. During 2009-2012 we enrolled 313 patients a multicentre prospective study Peru, 45 (14·4%) whom had confirmed HSV infection. Of 38 with known type, 84% HSV-1 16% HSV-2. Patients infection were significantly more likely to present summer months (44·4% vs. 20·0%, P = 0·003) have nausea (60·0% 39·8%,...
Neuromyelitis Optica Spectrum Disorder (NMOSD) is a rare systemic autoimmune disease which sometimes found in association with other disorders including Sjogren's syndrome. Neurological manifestations occur 20% to 25% of diagnosed cases Sjögren's syndrome; however, less than 5% patients syndrome have neurological as the initial presenting feature We report case an elderly female longitudinal myelitis who had positive antibody aquaporin-4 (NMO-IgG) and El trastorno del espectro de la...
La Esclerosis Múltiple (EM) es una enfermedad crónica del sistema nervioso central, para la cual aún no hay cura definitiva; sin embargo, existe diversa variedad de terapias con el objetivo modificar curso natural enfermedad, que promueve inclusión constante nuevas estrategias terapéuticas. Objetivo: Sociedad Peruana Neurología, por encargo Ministerio Salud, convocó a un comité expertos elaborar guía práctica clínica diagnóstico y tratamiento EM. Método: Se realizó búsqueda evaluación guías...
Stroke is the leading cause of neurological impairment in South American Andean region. However, epidemiology stroke region has been poorly characterized.
Multicenter collaborative networks are essential for advancing research and improving clinical care a variety of conditions. Research particularly important central nervous system infections, which remain difficult to study due their sporadic occurrence requirement collection testing cerebrospinal fluid. Establishment long-term in resource-limited areas also facilitates diagnostic capacity building, surveillance emerging pathogens, provision appropriate treatment where needed. We review our...
Purpose To summarize the medical literature related to diagnosis of bilateral medial medullary infarction (MMI) mimicking GBS. Methods We identified all published case studies in five databases until February 2024. performed a narrative synthesis develop differential criteria on included cases. A report is also presented. Results present patient with asymmetric and progressive motor weakness, bulbar dysfunction, albuminocytologic dissociation cerebrospinal fluid (CSF), negative brain CT scan...