- Peripheral Neuropathies and Disorders
- Dementia and Cognitive Impairment Research
- Multiple Sclerosis Research Studies
- Aging, Health, and Disability
- Genetics and Neurodevelopmental Disorders
- Neurological and metabolic disorders
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Syncope and Autonomic Disorders
- Hereditary Neurological Disorders
- Migraine and Headache Studies
- Intracranial Aneurysms: Treatment and Complications
- Epilepsy research and treatment
- Cerebrospinal fluid and hydrocephalus
- Cholinesterase and Neurodegenerative Diseases
- HIV/AIDS Research and Interventions
- Parasitic infections in humans and animals
- Autoimmune Neurological Disorders and Treatments
- HIV-related health complications and treatments
- Systemic Sclerosis and Related Diseases
- HIV Research and Treatment
- Health, Medicine and Society
- Sphingolipid Metabolism and Signaling
- Vascular Malformations Diagnosis and Treatment
- Cerebrovascular and genetic disorders
- Long-Term Effects of COVID-19
Instituto Nacional de Enfermedades Neoplásicas
2020-2024
Instituto Nacional de Ciencias Neurológicas
2012-2024
Medicina
2021
Hospital Nacional Dos de Mayo
2014-2018
Instituto Nacional de Neurología y Neurocirugía
2012-2015
Medico
2014
National University of San Marcos
2013-2014
Universidad de San Martín de Porres
2014
Dementia is a worldwide public health problem and there are several diagnostic tools for its assessment. The aim of this study was to evaluate the performance Memory Alteration Test (M@T) discriminate between patients with early Alzheimer's disease (AD), amnestic mild cognitive impairment (a-MCI), subjects cognitively healthy status (CHS).The discriminative validity assessed in sample 90 AD, 45 a-MCI, 180 CHS. Clinical, functional, studies were independently performed blinded fashion gold...
Dementia is a major cause of dependency and disability among older persons, imposes huge economic burdens. Only few cost-of-illness studies for dementia have been carried out in middle low-income countries. OBJECTIVE: The aim this study was to analyze costs demented patients private clinic Lima, Peru. Methods. We performed retrospective, cohort, 3-month by extracting information from medical records assess the use both healthcare non-healthcare resources. total disease were broken down into...
OBJECTIVE: The aim of this study was to evaluate caregiver burden based on Zarit Burden Interview (ZBI) and depression in caregivers the Beck Depression Inventory-II (BDI-II). METHODS: Literate individuals, 18 years or older, who spoke Spanish as their native language were included. Demographic characteristics: Age, sex, education, relationship person with dementia, length time caregiving, other sources help for caring, impact household economy, family support, perception impaired health;...
Introduction: Ultra–longitudinally extensive transverse myelitis (uLETM) is defined as an inflammatory lesion involving 10 or more spinal cord segments. The aim of our study to describe the clinical and radiological features this atypical form myelitis. Methods: We conducted a descriptive cross-sectional data from 57 patients older than 18 years diagnosed with longitudinally Nineteen cases were classified uLETM. Results: Twelve 19 women, age ranged between 76 years, main aetiology was...
The cerebrovascular complications in neurocysticercosis (NC) are uncommon. However, their pathophysiology remains unknown, but may be likely related to chronic inflammatory processes the subarachnoid space (basal meningitis). Alterations of cytokines cerebrospinal fluid and sera correlate with vasospasm SAH; these mediators NC induce aneurysm formation.A 7-year retrospective study a neurological referral center (Instituto Nacional de Neurología y Neurocirugía), showed 3 cases hemorrhage...
Background: The diagnosis of the behavioral variant frontotemporal dementia (bvFTD) can be especially challenging and is relatively underdiagnosed. There scarce information on training attitudes from care providers facing bvFTD in settings with limited resources. We aim to describe clinical knowledge neurologists, psychiatrists, residents Peru. Methods: Potential participants received invitations by email complete an online questionnaire. In addition, we reviewed 21 curricula undergraduate...
BackgroundMS is unpredictable regarding clinical symptoms; however, certain symptoms represent the preferred localization of white matter lesions such as brainstem, spinal cord; or optic nerve.ObjectivesTo investigate epidemiological, clinical, and imaging characteristics MS patients in a national referral center Peru, to evaluate whether type symptom at onset relates with time making an diagnosis.MethodsRetrospective study Instituto Nacional de Ciencias Neurológicas between January 2010...
Stroke is the leading cause of neurological impairment in South American Andean region. However, epidemiology stroke region has been poorly characterized.
Introducción: La trombosis venosa cerebral, una enfermedad cerebro vascular rara, afecta fundamentalmente niños y mujeres en edad fértil. Caso clínico: Paciente de sexo femenino, 45 años edad, evaluada otro establecimiento salud donde le diagnosticaron fiebre tifoidea, acudió a emergencia refiriendo un tiempo 14 días, con cefalea frontal moderada intensidad, náuseas vómitos, fue hospitalizada por probable hemorragia subaracnoidea. Al examen físico tenía funciones vitales estables neurológico...
La persistencia de la arteria trigeminal es una alteración vascular infrecuente y representa permanencia, después del nacimiento, comunicación entre el sistema carotideo vertebro-basilar.Esta se ha asociado a existencia otras alteraciones morfología cerebral condiciones clínicas variadas.Reportamos tres casos trigeminal, dos como hallazgo incidental en pacientes con sintomatología transitoria uno un cuadro hemorragia subaracnoidea, identificados mediante reconstrucción tridimensional
Recently the term Autoimmune/Inflammatory Syndrome induced by Adjuvants has been proposed to describe different clinical conditions, among them post-vaccinal phenomena like demyelinating diseases. We aim add knowledge on possible association of vaccines and development present case a 38-year-old female that developed brainstem syndrome after vaccination with COVID-19 BBIBP-CorV Sinopharm Vaccine. The final diagnosis extensive work-out was Neuromyelitis Optica spectrum disorder positive...
La enfermedad de Alzheimer y la epilepsia no solo comparten edad avanzada como un factor riesgo, si también compartirían mecanismos subyacentes en su etiología. Las crisis epilépticas generalmente fueron reportadas estadios tardíos Alzheimer; sin embargo los pacientes con familiar mutaciones PSEN1, PSEN2 proteína precursora del amiloide tienen mayor riesgo desarrollar aún tempranos enfermedad. Por otro lado lóbulo temporal podría generar per sé compromiso memoria esclerosis hipocampal...
La persistencia de la arteria trigeminal es una alteración vascular infrecuente y representa permanencia, después del nacimiento, comunicación entre el sistema carotideo vertebro-basilar. Esta se ha asociado a existencia otras alteraciones morfología cerebral condiciones clínicas variadas. Reportamos tres casos trigeminal, dos como hallazgo incidental en pacientes con sintomatología transitoria uno un cuadro hemorragia subaracnoidea, identificados mediante reconstrucción tridimensional...
Depresión y demencia, sobre todo enfermedad de Alzheimer (EA) son entidades críticas en la salud mental tercera edad. Ambas condiciones disminuyen calidad vida e incrementan el deterioro actividades diaria individuos EA tiene pobre pronóstico al ser una neurodegenerativa; mientras que depresión es básicamente reversible. Los estudios seguimiento longitudinal caso-control reportan estrecha asociación entre inicio tardío cognitivo progresivo, pues se ha demostrado riesgo incremento 2 a 5 veces...