Obstructive sleep apnea (OSA) is associated with increased cardiovascular (CV) morbidity and mortality. Endocan a surrogate endothelial dysfunction marker that may be CV risk factors. In this study, we tested whether serum endocan biomarker for OSA. Serum levels were measured at baseline in 40 patients OSA healthy controls after 3 months of continuous positive airway pressure (CPAP) treatment the All participants evaluated by full polysomnography. Flow-mediated dilatation (FMD) carotid...

In our study, the effect of hesperetin on inflammatory and oxidative status in trinitrobenzene sulfonic acid (TNBS)-induced experimental colitis model was investigated through different methods. Eighteen Wistar albino male rats were divided to three groups: Group I (Control, n = 8; 1 ml physiological saline), II (Colitis, TNBS), III (Hesperetin, TNBS 100 mg/kg hesperetin). Macroscopic microscopic scores calculated determine damage colon at end experiment. Serum tumor necrosis factor-α...

We investigated the gastroprotective effect of apricot kernel oil on ethanol induced gastric ulcer in rats. Male Wistar albino rats were divided into control, and + groups. The fatty acid composition was determined using GC-MS. A index defined as area percentage mucosa consisting ulcerated tissue. Gastric tissue by TUNEL staining for apoptosis, immunohistochemical iNOS staining, measurement IL-10 IL-6 expression ELISA assays catalase, malondialdehyde superoxide dismutase. group exhibited a...

Arsenic exposure is increasing in communities due to environmental pollution and industrial development. toxic organ systems because it causes oxidative stress, enzymatic inhibition, damage protein structures. The liver, for example, an that may be damaged by arsenic, this cause various clinical conditions like hepatic failure or cancer. Melatonin a hormone acts antioxidant, anti-inflammatory agent, cytoprotective agent. In study, we aimed evaluate melatonin's protective effects on livers...

MicroRNAs (miRNAs) are non-coding RNA molecules that serve as regulators following gene expression transcription. While studies have investigated the role of miRNAs in pathogenesis essential hypertension (HT), very few considered their place resistant (RH). The purpose this study was to investigate levels miRNA 21 and 155 RH relationships with aldosterone.Thirty-two normotensive patients, 30 newly diagnosed HT 20 patients were included study. Patients' demographic data recorded, office blood...

Prenatal stress is a significant risk factor affecting pregnant women and fetal health. In the present study, we aimed to investigate effect of immobility at different periods pregnancy on oxidative stress, inflammation, placental apoptosis intrauterine growth retardation in rats.Fifty adult virgin female Wistar albino rats were used. Pregnant exposed 6 h/day immobilization wire cage stages pregnancy. Groups I II (Day 1-10 group) sacrificed 10th day pregnancy, Group III, IV (10-19th-day...

Objectives As a result of developed generalized inflammation, the main prognostic factor determining morbidity and mortality in coronavirus disease 2019 (COVID-19) patients is acute respiratory distress syndrome. The purpose our study was to define (1) laboratory tests that will contribute diagnosis follow-up COVID-19 patients, (2) differences between laboratory-confirmed (LC), unconfirmed (LUC), control (C) groups, (3) variation groups acute-phase reactants biomarkers can be used as an...

Irritable bowel syndrome (IBS), a functional disorder of the bowel, has been thought to result from immune activation. The aim this study was evaluate macrophage migration inhibitory factor (MMIF) and monocyte chemotactic protein-1 (MCP-1) levels in IBS patients.We enrolled 30 patients healthy controls. MMIF MCP-1 all controls were detected using commercial enzyme-linked immunosorbent assay kits.Serum markedly higher than White blood cell, neutrophil, lymphocyte, monocyte, eosinophil,...

Hypertension is one of the leading causes cardiovascular mortality. Although pathogenetic process involved not yet fully understood, disease involves endothelial damage and inflammation. Calprotectin an inflammatory marker that rises in parallel with activity conditions such as systemic diseases, infection, atherosclerosis. The purpose this study was to evaluate inflammation through serum calprotectin levels newly diagnosed primary hypertension patients.Forty-nine hypertensive patients 38...

The aim of this study is to determine biomarkers, which may be used in order understand the pathophysiology, diagnosis, progression surveillance/monitoring, and treatment efficacy high graded glial tumors.Radiological imaging diagnosis relapse surveillance tumors sometimes insufficient. There need for additional methods rule out contradictory circumstances.Using enzyme like immune sorbent assay method, E-Cadherin, Tenascin C, Tetraspanin 8, Survivin VEGF121 levels were investigated serum...

<b><i>Introduction:</i></b> Chronic kidney disease (CKD) is a widespread health problem, in which mortality most frequently due to cardiovascular diseases. Microfibrillar-associated protein 4 (MFAP4) an extracellular matrix protein. MFAP4 involved several biological processes, particularly the maintenance of vascular integrity and remodeling. Our review literature revealed no data concerning levels CKD its relationship with myocardial functions....

<title>Abstract</title> Background Although high-dose biotin interference is now considered in automated immunoassays, it has not yet been detected manually studied research kits, especially with enzyme-linked immunosorbent assay (ELISA), and the possibility of these kits demonstrated. The aims our study were to determine effects on various parameters, including leptin, leptin receptor (LEPR), ghrelin, acylated deacylated ghrelin (GHSR), kisspeptin (KISS1), (KISS1R), preptin, peroxisome...

This study aims to research whether gensini scoring of white blood cells and their subgroups hemoglobin (Hb), hematocrit (Htc), erythroscyte computational tests are related, through retrospectively evaluating complete cell counts patients who underwent coronary angiography with artery disease (CAD) early diagnosis. Files 267 patients, 113 women 154 men over the age 18, came Namık Kemal University Research Practice Hospital in August 2011 January 2012 CAD diagnosis, were scanned...