A5088842697- Aquaculture disease management and microbiota
- Invertebrate Immune Response Mechanisms
- Fish biology, ecology, and behavior
- Genetics, Aging, and Longevity in Model Organisms
- Marine Sponges and Natural Products
- Physiological and biochemical adaptations
- Genomics and Phylogenetic Studies
- interferon and immune responses
- Coral and Marine Ecosystems Studies
- Neurobiology and Insect Physiology Research
- Protein Hydrolysis and Bioactive Peptides
- Identification and Quantification in Food
- Ichthyology and Marine Biology
- Viral Infections and Vectors
- ATP Synthase and ATPases Research
- Cybersecurity and Cyber Warfare Studies
- Parasites and Host Interactions
- Ocean Acidification Effects and Responses
- Cholinesterase and Neurodegenerative Diseases
- Neuroinflammation and Neurodegeneration Mechanisms
- International Relations and Foreign Policy
- Plant Virus Research Studies
- Global Peace and Security Dynamics
- Toxoplasma gondii Research Studies
- Echinoderm biology and ecology
University of Miami
2018-2024
Since 2014, corals within Florida’s Coral Reef have been dying at an unprecedented rate due to stony coral tissue loss disease (SCTLD). Here we describe the transcriptomic outcomes of three different SCTLD transmission experiments performed Smithsonian Marine Station and Mote Laboratory between 2019 2020 on Orbicella faveolata Montastraea cavernosa. Overall, diseased O. had 2194 differentially expressed genes (DEGs) compared with healthy colonies, whereas M. cavernosa 582 DEGs colonies. Many...
Abstract The immune repertoires of mollusks beyond commercially important organisms such as the pacific oyster Crassostrea gigas or vectors for human pathogens like bloodfluke planorb Biomphalaria glabrata are understudied. Despite being an model neural aging and role inflammation in neuropathic pain, repertoire Aplysia californica is poorly understood. Recent discovery a neurotropic nidovirus has highlighted need better understanding immunome. To address this gap literature, reference...
Abstract Long-read sequencing is revolutionizing de-novo genome assemblies, with continued advancements making it more readily available for previously understudied, non-model organisms. Stony corals are one such example, long-read assemblies now starting to be publicly available, opening the door a wide array of ‘omics-based research. Here we present new assembly endangered Caribbean star coral, Orbicella faveolata , using PacBio circular consensus reads. Our improved contiguity (51 versus...
Aging is associated with cognitive declines that originate in impairments of function the neurons make up nervous system. The marine mollusk Aplysia californica (Aplysia) a premier model for system uniquely suited to investigation neuronal aging due identifiable and molecular techniques available this model. This study describes processes two populations sensory by applying RNA sequencing technology across process (age 6 12 months). Differentially expressed genes clustered into 4-5 coherent...
Abstract The red sea urchin, Mesocentrotus franciscanus , is one the earth’s longest-lived animals, reported to live more than 100 years with indeterminate growth, life-long reproduction and no increase in mortality rate age. To gain insight into mechanisms associated longevity negligible senescence, age-related transcriptional profiles were examined tissues of urchin. Genome-wide profiling using RNA-Seq revealed few changes gene expression muscle esophagus tissue. In contrast, radial nerve...
Aging of the nervous system is typified by depressed metabolism, compromised proteostasis, and increased inflammation that results in cognitive impairment. Differential expression analysis a popular technique for exploring molecular underpinnings neural aging, but technical drawbacks methodology often obscure larger patterns. Co-expression offers robust alternative allows identification networks genes their putative central regulators. In an effort to expand upon previous work aging marine...
Although Alzheimer's disease (AD) is the most common form of dementia in United States, development therapeutics has proven difficult. Invertebrate alternatives to current mammalian AD models have been successfully employed study etiology molecular hallmarks AD. The marine snail Aplysia californica offers a unique and underutilized system which physiological, behavioral, impacts Mapping proteome humans cross-referencing with two databases genes interest research identified 898 potential...
Abstract The Gulf toadfish, Opsanus beta , within the family Batrachoididae, plays an important role ecologically and as a comparative research model. Only 4 genome assemblies are available for Batrachoids, with three being highly fragmentary not up to current assembly standards. Here we present new, de novo transcriptome toadfish using PacBio long read technology. final is among largest teleost genomes at 2.1 gigabases. This new improves significantly upon currently reference scaffold count...
The family Batrachoididae are a group of ecologically important teleost fishes with unique life histories, behavior, and physiology that has made them popular model organisms. remain understudied in the realm genomics, only four reference genome assemblies available for family, three being highly fragmented not up to current assembly standards. Among these is Gulf toadfish, Opsanus beta, organism serotonin which recently been bred captivity.
Abstract The immune repertoires of mollusks beyond commercially important organisms such as the pacific oyster Crassostrea gigas or vectors for human pathogens like bloodfluke planorb Biomphalaria glabrata are understudied. Despite being an model neural aging and role inflammation in neuropathic pain, repertoire Aplysia californica is poorly understood. Recent discovery a neurotropic nidovirus has highlighted need better understanding immunome. To address this gap literature, reference...