Patricia Blackwelder

ORCID: 0000-0003-0989-2976
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About
Contact & Profiles
Research Areas
  • Coral and Marine Ecosystems Studies
  • RNA Interference and Gene Delivery
  • Immunotherapy and Immune Responses
  • Calcium Carbonate Crystallization and Inhibition
  • Click Chemistry and Applications
  • Geology and Paleoclimatology Research
  • Marine Bivalve and Aquaculture Studies
  • Marine Biology and Ecology Research
  • Marine Sponges and Natural Products
  • Marine and coastal ecosystems
  • Marine and coastal plant biology
  • Isotope Analysis in Ecology
  • Carbon and Quantum Dots Applications
  • Nanocluster Synthesis and Applications
  • Marine Biology and Environmental Chemistry
  • Methane Hydrates and Related Phenomena
  • Aquaculture disease management and microbiota
  • Atmospheric chemistry and aerosols
  • Paleontology and Stratigraphy of Fossils
  • Advanced Nanomaterials in Catalysis
  • Algal biology and biofuel production
  • Ocean Acidification Effects and Responses
  • Marine and environmental studies
  • Nanoparticles: synthesis and applications
  • Graphene and Nanomaterials Applications

University of Miami
2014-2023

Nova Southeastern University
2007-2023

American Orchid Society
2017-2019

Commissariat à l'Énergie Atomique et aux Énergies Alternatives
1986

Centre National de la Recherche Scientifique
1986

University of Hawaii at Hilo
1986

Direction des énergies
1986

University of Oslo
1982

Woods Hole Oceanographic Institution
1982

University of South Carolina
1973-1976

One prevention and therapeutic strategy for diseases associated with peptide or protein fibrillation is to inhibit delay the process. Carbon dots (C–Dots) have recently emerged as benign nanoparticles replace toxic quantum attracted great attention because of their unique optical properties potential applications in biological systems. However, effect C-Dots on has not been explored. In this vitro study, human insulin was selected a model investigate fibrillation. Water-soluble fluorescent...

10.1021/cm504572b article EN Chemistry of Materials 2015-02-10

Significance Phosphorus (P) deposition from aerosols can stimulate primary productivity in P-depleted marine and terrestrial ecosystems. We tested the hypothesis that African dust fertilizes Amazon Basin Tropical Atlantic Ocean (TAO) by measuring windborne dust, P, soluble P samples collected at a coastal site on northeastern edge of Amazon. Using satellite data models, we identified previously underestimated source P: biomass burning aerosol transported southern Africa supply to Amazon,...

10.1073/pnas.1906091116 article EN Proceedings of the National Academy of Sciences 2019-07-29

Research Article| May 01, 1992 Biochemical and ultrastructural evidence for the origin of whitings: A biologically induced calcium carbonate precipitation mechanism L. Robbins; Robbins 1Department Geology, University South Florida, Tampa, Florida 33620 Search other works by this author on: GSW Google Scholar P. Blackwelder 2Marine Geology Geophysics, Rosenstiel School Marine Atmospheric Science, 4600 Rickenbacker Causeway, Miami, 33149 Author Article Information Publisher: Geological Society...

10.1130/0091-7613(1992)020<0464:baueft>2.3.co;2 article EN Geology 1992-01-01

Bone-related diseases and dysfunctions are heavy burdens on our increasingly aged society. In this study, carbon dots have been introduced as highly promising biomaterials for bone-related bioimaging drug delivery due to their high affinity specificity bone-binding properties.

10.1039/c7nr05731h article EN Nanoscale 2017-01-01

DNA-based vaccines hold promise to outperform conventional antigen-based by virtue of many unique features. However, DNA have thus far fallen short expectations, due in part poor targeting professional antigen-presenting cells (APC) and low immunogenicity. In this study, we describe a new platform for effective selective delivery APCs vivo that offers intrinsic immune-enhancing characteristics. This is based on conjugation fifth generation polyamidoamine (G5-PAMAM) dendrimers, DNA-loading...

10.1158/0008-5472.can-11-1766 article EN Cancer Research 2011-10-11

Background Marine sponge species are of significant interest to many scientific fields including marine ecology, conservation biology, genetics, host-microbe symbiosis and pharmacology. One the most intriguing aspects "holobiont" system is unique physiology, interaction with microbes from environment development a complex commensal microbial community. However, intraspecific variability temporal stability sponge-associated bacterial symbionts remain relatively unknown. Methodology/Principal...

10.1371/journal.pone.0038204 article EN cc-by PLoS ONE 2012-06-12

Research Article| June 29, 2017 Microbially mediated organomineralization in the formation of ooids Mara R. Diaz; Diaz * 1CSL–Center for Carbonate Research, Department Marine Geosciences, Rosenstiel School and Atmospheric Science, University Miami, Florida 33149, USA *E-mail: mdiaz@rsmas.miami.edu Search other works by this author on: GSW Google Scholar Gregor P. Eberli; Eberli Patricia Blackwelder; Blackwelder 2Center Advanced Microscopy, Miami–Coral Gables, 33124, Brian Phillips; Phillips...

10.1130/g39159.1 article EN Geology 2017-06-29

Marine teleostean fish are hypo-osmotic to seawater. As part of a multiorgan osmoregulatory strategy they drink seawater and selectively absorb water minerals across the intestinal epithelium. Notably, divalent cations (Ca2+ Mg2‒) left behind. We report here that in gulf toadfish, Opsanus beta, ionic by-products osmoregulation intestine contribute de novo formation carbonate mineral, tentatively identified as calcian kutnohorite. Our data suggest mineralization is general feature marine...

10.4319/lo.1991.36.6.1227 article EN Limnology and Oceanography 1991-09-01

Abstract Highly photoluminescent gel‐like carbon dots (G‐CDs) were successfully synthesized for the first time by a rapid one‐step solvothermal synthesis approach with citric acid and 1,2‐ethylenediamine as precursors. Their nature was revealed Tyndall coagulation effects, which elucidated negative ζ potential value. The influences of temperature on properties sizes these G‐CDs analyzed, best method maximum quantum yield identified. resulting products emitted blue photoluminescence under UV...

10.1002/cphc.201700038 article EN ChemPhysChem 2017-02-07

Abstract Photoluminescent carbon dots (CDs) fractions have been isolated from a gel‐like material (GM), which was synthesized using convenient one‐step solvothermal route. In terms of purification, size exclusion chromatography (SEC) and dialysis were compared with acetone wash, revealed the advantage wash. The pre‐purified GM wash (A‐GM) further by reversed‐phase preparative thin layer (TLC) acetonitrile−water mixture (7 : 3; v /v w ) as developing solvent. As result, there four...

10.1002/cphc.201800248 article EN ChemPhysChem 2018-06-01

Five lead-resistant strains of Staphylococcus aureus were isolated. Plasmid-free lead-sensitive variants obtained from the three plasmid-bearing strains. Lead-resistant tolerated an approximately 600 x higher Pb(NO3)2 concentration than Both types initially bound lead, but only resistant accumulated metal as intracellular lead-phosphate.

10.1111/j.1574-6968.1996.tb08610.x article EN FEMS Microbiology Letters 1996-12-01

Background.Amphotericin B (AmB), the most effective drug against leishmaniasis, has serious toxicity.As Leishmania species are obligate intracellular parasites of antigen presenting cells (APC), an immunopotentiating APCspecific AmB nanocarrier would be ideally suited to reduce dosage and regimen requirements in leishmaniasis treatment.Here, we report a that results treatment shortening cutaneous mouse model, while also enhancing L. major specific T-cell immune responses infected...

10.1093/infdis/jit378 article EN The Journal of Infectious Diseases 2013-07-29

Herein we report an ultrasonic- and photobased synthetic approach for the production of size-selective SrTiO3 nanomaterials that are surface-decorated with Pd nanoparticle cocatalysts application as photocatalysts organic dye degradation. Control over final size was achieved through selection both reagent concentrations stoichiometries, allowing ability to generate structures sizes between 50 155 nm. nanoparticles were subsequently photochemically deposited onto surface oxide materials serve...

10.1021/acsanm.0c01086 article EN ACS Applied Nano Materials 2020-04-24

The inflammatory response appears to play a critical role in clotting which neutrophil extracellular traps (NETs) are the major drivers of thrombosis acute ischemic stroke (AIS). inflammasome is an innate immune complex involved activation interleukin (IL)-18 and IL-1β through caspase-1, but whether plays NETosis AIS remains poorly understood. Here we assessed levels signaling proteins NETs their association with clinical procedural outcomes mechanical thrombectomy for AIS. Electron...

10.3389/fphar.2020.607287 article EN cc-by Frontiers in Pharmacology 2021-01-22

Abstract The equatorial North Atlantic Ocean (NAO) is a nutrient‐limited ecosystem that relies on the deposition of long‐range transported iron (Fe)‐containing aerosols to stimulate primary productivity. Using microscopy, we characterized supermicron and supercoarse mode African western NAO in boreal winter/spring. We detected three particle types including dust, biological aerosol particles, freshwater diatoms (FDs). FDs contained 4% Fe by weight due surficial dust inclusions may be...

10.1029/2020gl090476 article EN Geophysical Research Letters 2021-02-03

Benthic foraminifera influenced by the Mississippi River plume and seasonal hypoxia were assessed from Louisiana inner-continental shelf sediment samples. Surface assemblages representative of in-situ populations as established staining techniques. Community diversity richness/evenness analyses indicate three regimes: high stress (sediment dominated), intermediate (hypoxia low (low accumulation/high oxygen). Epistominella vitrea Buliminella morgani are useful tracers rapid accumulation rate...

10.1016/1040-6182(95)00018-e article EN cc-by-nc-nd Quaternary International 1996-01-01
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