Abstract Enhancing the activity of oxygen reduction reaction (ORR) is crucial for fuel cell development, and hydrophobic species are known to increase ORR activity. This paper reports that caffeine enhanced specific Pt(111) 11-fold compared without in a 0.1 M HClO 4 aqueous solution. Moreover, increased Pt(110) 2.5-fold; however, Pt(100) was unaffected. The infrared (IR) band PtOH (blocking ORR) decreased all surfaces. Caffeine adsorbed with its molecular plane perpendicular surfaces tilted...

Dysregulation of miR-182 and miR-183 has been implicated in the progression several human cancers. Our previous study showed that are upregulated malignant mesothelioma. However, their biological functions remain unclear. We performed in-situ hybridization to analyze expression tissues. Functional analysis was by treatment two mesothelioma cell lines (ACC-MESO1 CRL-5915) with inhibitors. RT-PCR western blot were conducted FOXO1, a known target both miR-183. Mesothelioma cells treated FOXO1...

The differential diagnosis of epithelioid mesothelioma from lung adenocarcinoma using immunohistochemistry is improving. However, immunohistochemical markers with high sensitivity and specificity have yet to be identified. In this study, we investigated the utility sex-determining region Y box 6 (SOX6) as a novel marker, identified by analyzing previous gene expression data. Immunohistochemically, SOX6 was present in 53 54 (98%) cases mesothelioma, compared its only 5 69 (7%) adenocarcinoma....

Malignant mesothelioma is a major asbestos-related cancer with prolonged time lapse from the first exposure of asbestos to development mesothelioma. Most patients show very poor prognosis, thus, an urgent improvement its treatment required by novel therapeutic strategies. RNA interference (RNAi) powerful tool in post-genomic research and therapy through inhibition gene expression. In present study, we analyzed function PIM1 on cell lines knockdown siRNA transfection. Here, report that...

Aims The process of differential diagnosis between epithelioid mesothelioma and lung adenocarcinoma has been progressing; however, there are no absolute immunohistochemical markers with which to definitively diagnose mesothelioma. aim this study was search for a novel negative marker Methods results We immunohistochemically studied the applicability mucin 21 ( MUC 21), identified in our previous study, as novel, diagnostic Seventy mesotheliomas 70 adenocarcinomas were investigated expression...

Recently, the number of older people and reduction in infant birth rates Japan have increased. Elderly against younger increased to more than 28.9% 2020. According Japanese aging society, a welfare pneumatic device rehabilitate temporally injured elderly disabled has been actively researched developed. However, developed rehabilitation is almost always used for patient who not bedridden. Therefore, joint bedridden given only passive exercise, by physical therapist (PT). In this study, order...

Malignant pleural mesothelioma is a notorious human malignancy. Despite combination chemotherapy with cisplatin and pemetrexed, the majority of patients advanced malignant have poor prognosis. MicroRNAs (miRNAs/miRs) are short non-coding RNAs that regulate various biological processes by binding to 3'-untranslated region target gene mRNAs suppressing their expression. Since abnormal expression patterns miRNAs common feature in malignancies, number them been researched as potential...

The histological classification of non-small cell lung cancer (NSCLC) is essential in determining new cancer-specific targeted therapies. However, the accurate typing poorly differentiated difficult, particularly for squamous carcinoma and adenocarcinoma with limited immunohistochemical markers. Thus, novel markers are required. We assumed possibility expression glypican-1 carcinoma.The microarray dataset GSE43580 from Gene Expression Omnibus database were analyzed confirming gene carcinoma....

The oxygen reduction reaction (ORR) on the low- and high-index planes of Pt modified with a protonic ionic liquid ([7-methyl-1,5,7-triazabicyclo(4.4.0)dec-5-ene][bis(pentafluoroethylsulfonyl)imide], referred to here as [MTBD][beti]) was studied in 0.1 M perchloric acid solution. specific activity ORR Pt(1 1 1) [MTBD][beti] 3.1 times higher than that unmodified 1), while deactivated 0 0). slightly enhanced n(1 1)–(1 (where n = 2–9). These results show larger (1 terrace is essential for marked...

Histological distinction between epithelioid mesothelioma (EM) and reactive mesothelial hyperplasia (RMH) can be challenging. The aim of this study was to assess the diagnostic utility Survivin, Ki‑67, loss BRCA1‑associated protein 1 (BAP1) expressions in distinguishing EM from RMH using immunohistochemistry. Formalin‑fixed, paraffin‑embedded specimens 78 cases 80 were immunohistochemically examined for BAP1, Ki‑67. In addition, receiver operating characteristic curve analyses performed...

Early injection of anti-mamushi venom serum (antiserum) is believed to be effective for the treatment patients with mamushi bites. However, there no firm information that indicates time range constituting "early" injection. We tried quantify cut-off antiserum brings favorable clinical courses by clarifying relationship between and outcome.We retrospectively analyzed relationships after bite, antiserum, swelling grades, laboratory values.The in severe cases was significantly delayed as...

all-words 語義曖昧性解消(以下 WSD (word sense disambiguation))とは文書中のすべての単語の語義ラベルを付与するタスクである.単語の語義は文脈,すなわち周辺の単語によって推定でき,周辺の単語同士が類似している場合中心の単語同士の語義も類似していると考える.そこで本研究では,対象単語とその類義語群から周辺単語の分散表現を作成し,ユークリッド距離を計算することで対象単語の語義を予測した.また,語義の予測結果をもとにコーパスを語義ラベル列に変換し,語義の分散表現を作成した.語義の分散表現を用いて周辺単語ベクトルを作成し直し,再び語義の予測を行った.コーパスには分類語彙表番号がアノテーションされた『現代日本語書き言葉均衡コーパス』(BCCWJ) を利用した.本研究では分類語彙表における分類番号を語義とし,類義語も分類語彙表から取得した.本研究では,提案手法とランダムベースライン,Pseudo Most Frequent Sense (PMFS),Yarowsky の手法,LDAWN を比較し,提案手法が勝ることを示した.

Malignant mesothelioma is a highly aggressive tumor, and an effective strategy for its treatment not yet available. Long non‑coding RNAs (lncRNAs) have been reported to be associated with various biological processes, including the regulation of gene expression cancer‑related pathways. Among lncRNAs, plasmacytoma variant translocation 1 (PVT1) acts as tumor promoter in several human cancers, but mechanism action has elucidated. Increased PVT1 was identified ACC‑MESO‑1, ACC‑MESO‑4, CRL‑5915,...

In this study, our purpose was to develop a method analyze the presence or absence of contact between ball and fingertip during release phase throwing motion in American football, verify its validity. Further, using analysis developed study for analysis, we tried phase. method, is analyzed only position coordinates acquired by capture system. The boundary positioned at distance each thickness from surface formulated into mathematical expression. If marker attached located closer than...

Night baths are an essential and beloved tradition in Japanese households. The main purpose of taking a bath at the end day, besides hygiene, is relaxation. aging population rapidly growing Japan, as one three people approaching age 65 years or older. Furthermore, with progress nuclear families, number households only elderly need for care increasing. In recent years, experienced burns caused by hot water during bathing. We report two cases people. first case 68-year-old woman who presented...