A5036222209- Traumatic Brain Injury and Neurovascular Disturbances
- Antimicrobial Resistance in Staphylococcus
- Venomous Animal Envenomation and Studies
- Rabies epidemiology and control
- Ion channel regulation and function
- Autophagy in Disease and Therapy
- Alcoholism and Thiamine Deficiency
- Vitamin K Research Studies
- Streptococcal Infections and Treatments
- Muscle Physiology and Disorders
- Neurological Disorders and Treatments
- Infective Endocarditis Diagnosis and Management
- Nosocomial Infections in ICU
- Sepsis Diagnosis and Treatment
- Intensive Care Unit Cognitive Disorders
- Epilepsy research and treatment
- Sirtuins and Resveratrol in Medicine
- Emergency and Acute Care Studies
- Cardiac Arrest and Resuscitation
- Neonatal and fetal brain pathology
- Neonatal and Maternal Infections
- Vitamin C and Antioxidants Research
- Turtle Biology and Conservation
- Trauma and Emergency Care Studies
- Antibiotic Resistance in Bacteria
Sapporo Medical University
2023
Kumamoto University
2021-2022
Almeida Memorial Hospital
2014-2022
Saiseikai Suita Hospital
2022
American Public Health Association
2014-2017
Kagawa University Hospital
2016
Aging is associated with impairment of multiple organs, including skeletal muscle and heart. In this study, we investigated whether resveratrol, an activator NAD+-dependent protein deacetylase Sirtuin-1 (SIRT1), attenuates age-related sarcopenia cardiomyocyte hypertrophy in mice. Treatment mice resveratrol (0.4 g/kg diet) from 28 weeks age for 32 prevented aging-associated shortening rotarod riding time. the tibialis anterior (TA) muscle, histogram analysis showed that atrophic was increased...
We report a lethal case of mamushi (Gloydius blomhoffii) bite. An 84-year-old woman was bitten by snake on her right elbow. She initially treated at another hospital, however, because the swelling expanded and renal function worsened, she transferred to our hospital. Compartment syndrome, thrombocytopenia, respiratory arrest, elevated creatinine kinase lactose dehydrogenase levels were seen; failure progressed, ileus peritonitis due colon perforation occurred.The patient died 35 days after...
Aim The present study aimed to elucidate the clinical characteristics of non‐convulsive status epilepticus ( NCSE ) in patients with altered mental AMS ). Methods This single‐center retrospective comprised 149 who were hospitalized between March 1, 2015 and September 30, at emergency intensive care unit ICU Kagawa University Hospital (Kagawa, Japan). primary outcome was incidence. secondary comparison duration stay, hospital a favorable neurological outcome, as assessed using modified Rankin...
Early injection of anti-mamushi venom serum (antiserum) is believed to be effective for the treatment patients with mamushi bites. However, there no firm information that indicates time range constituting "early" injection. We tried quantify cut-off antiserum brings favorable clinical courses by clarifying relationship between and outcome.We retrospectively analyzed relationships after bite, antiserum, swelling grades, laboratory values.The in severe cases was significantly delayed as...
A 61-year-old woman was admitted to our hospital with a fever, nausea, diarrhea, and back pain. Her condition rapidly deteriorated, she transferred the intensive-care unit for mechanical circulatory support antibiotics, but died 40 hours after admission. Autopsy findings showed necrotic suppurative myocardial changes due group B Streptococcus (GBS). To date, only one case of bacterial myocarditis caused by GBS has been reported. We herein report myocarditis, etiology which is poorly...
場合 thiamine が活性化型である pyrophosphate に変換されず 1) ，これが関与するクエン酸回路 の代謝が阻害されるうえ 3) ，アルコールの代謝産物で ある acetaldehyde は の輸送や活性化を阻害 することから 5) ，アルコール依存症患者は脚気を起こ しやすいといえる。 今回我々は
It remains unclear how autonomic regulation modulates pathophysiological changes of sepsis. This study aims to analyze and clarify those in patients with suspected sepsis.In this single-centered, prospective, observational study, adult who had an infection, a quick Sequential Organ Failure Assessment score 2 or more at the emergency department, underwent intensive care were screened. Heart rate variability (HRV) serum adrenaline measured immediately after arrival. The primary outcome was...