A5050586003- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Health Systems, Economic Evaluations, Quality of Life
- Cardiovascular Function and Risk Factors
- Ion channel regulation and function
- Breast Cancer Treatment Studies
- Heart Rate Variability and Autonomic Control
- ECG Monitoring and Analysis
- Venous Thromboembolism Diagnosis and Management
- Breast Lesions and Carcinomas
- Pulmonary Hypertension Research and Treatments
- Obstructive Sleep Apnea Research
- Hydrogen's biological and therapeutic effects
- Genetic Neurodegenerative Diseases
- Legal principles and applications
- Neuroscience of respiration and sleep
- Cardiac Valve Diseases and Treatments
- Occupational and Professional Licensing Regulation
- Heart Failure Treatment and Management
- Inflammatory Bowel Disease
- Cardiomyopathy and Myosin Studies
- Vascular anomalies and interventions
- Cardiac Arrest and Resuscitation
Saitama Municipal Hospital
2024
Keio University
1989-2023
Keio University Hospital
2008-2023
Keio University Shonan Fujisawa
2017-2022
National Defense Medical College Hospital
2017
Hiroshima City Asa Citizens Hospital
2017
Citizens Specialty Hospitals
2017
Okayama University Hospital
2017
Chiba Cancer Center
2013-2017
Gunma Prefectural Cardiovascular Center
2017
Background:Hydrogen gas inhalation (HI) reduced infarct size and mitigated adverse left ventricular (LV) remodeling in a rat model of acute myocardial infarction (AMI). We designed prospective, open-label, rater-blinded clinical pilot study patients experiencing ST-elevated MI (STEMI).
Background Brugada syndrome ( BS ) is known to be 9 times more prevalent in males than females. However, little about the development of sick sinus female members with familial . Methods and Results Familial patients family members, both from our institutions collaborating sites that specialize clinical care , participated this study. We collected information on their genetic background, along inheritance patterns Detailed each case described. A total 7 families, including 25 (12 females 13...
Epicardiac conduction via the vein of Marshall (VOM) can bypass mitral isthmus (MI) line, making MI ablation difficult. This study aimed to assess contribution VOM in achieving block.This included 143 consecutive patients with nonparoxysmal atrial fibrillation who underwent initial ablation. They were retrospectively classified into two groups, a VOM-guided group (n = 28) and conventional 115), according use 2-Fr electrode catheter inserted VOM. The acute success rate block data assessed....
Background Atrial fibrillation and heart failure (HF) possess mutual risk factors share a common pathophysiological pathway. Tricuspid regurgitation (TR) is known predictor of adverse events in patients with HF. However, its implications on atrial early stage remain unknown. Methods Results Data 2211 without previous HF diagnosis were extracted from prospective, multicenter registry newly diagnosed fibrillation. TR was categorized as absent, mild, moderate, severe based the American Society...
Background Randomized clinical trials have demonstrated that catheter ablation (CA) for atrial fibrillation improves health-related quality of life (HRQoL). In daily practice, however, CA is performed on a wide range patients, and outcomes may vary. We aimed to examine baseline 1-year HRQoL patients with after in practice. Methods Results Using registry-based cohort study designed recruit newly referred 11 hospitals, we extracted data from 1097 consecutive who underwent between 2012 2019....
Abstract Background A novel measurement of the local impedance (LI) and electrograms recorded from micro‐electrodes on catheter tip has been developed. However, data during pulmonary vein (PV) ablation is not sufficient. We aimed to investigate utility this initial atrial fibrillation (AF) ablation. Methods investigated 111 representative radiofrequency applications in 7 AF patients without a history prior (6 males, age 68 [65‐72] years, 2 persistent AF). The strategy was PV isolation for...
Some patients with hypertrophic cardiomyopathy (HCM) develop systolic dysfunction, called the dilated phase of HCM (d-HCM), which is associated increased morbidity and mortality.We conducted a retrospective study using an database to clarify incidence, clinical characteristics, longterm outcomes d-HCM.We analyzed cohort consisting 434 (273 apical 161 non-apical HCM; 18 had obstructive HCM, 16 127 other HCM) diagnosed by echocardiography in our hospital between 1991 2010.The follow-up period...
Abstract Introduction An electrical superior vena cava (SVC) isolation from the right atrium (RA) sometimes can be challenging. For a safe and efficient SVC isolation, we aimed to visualize accurate position of SVC‐RA junction on three‐dimensional (3D) mapping system using decremental conduction properties in patients with atrial fibrillation (AF). Methods This study consisted 15 consecutive AF (11 males, age 59 ± 10 years). A 3D catheter was positioned region while delivering single...
A 62-year-old female had suffered from recurrent syncopal episodes triggered by physical and emotional stress since childhood. She no family history of sudden death. An intensive examination could not detect any structural disease, exercise testing provoked polymorphic ventricular ectopy followed tachycardia accompanied with syncope leading to a diagnosis catecholaminergic (CPVT). genetic analysis next generation sequencer identified homozygous W361X mutation in the CASQ2 gene. Careful...
The anatomical changes in pulmonary veins (PVs) after cryoballoon ablation (CBA) are unclear. We aimed to determine the morphological PVs and left atrium (LA) along with predictive factors for clinical PV stenosis.We analyzed data of 320 from 80 patients who underwent CBA atrial fibrillation (age: 62 ± 10 years, 59 males). All pre- post-procedural cardiac computed tomography. defined stenosis when cross-sectional area decreased by more than 50%.The average ostial LA volume significantly...
A 48-year-old woman with a history of bronchial asthma and allergic rhinitis presented cardiac arrest due to ventricular fibrillation was resuscitated by defibrillation. Coronary angiography revealed coronary vasospasm. Various antispastic agents were unable control recurrent spasms. We searched for other points intervention found significant increase in the eosinophil count. The patient received mepolizumab eosinophilia, which normalized Since then, has remained free from vasospasm,...
Abstract A 23‐year‐old female had been suffering from recurrent syncopal episodes during sleep since her childhood. She a family history of sudden death and QTc interval was remarkably prolonged to 537 ms Holter ECG revealed torsade de pointes, corresponding syncope. started on mexiletine shortened. Her symptoms were controlled after β‐blockers Ca‐blockers added. genetic analysis with next generation sequencer identified frameshift mutation at the C terminus KCNH2 gene. Here we present type...
Percutaneous coronary intervention for anomalous right artery (RCA) originating from the left cusp is challenging because of our current inability to coaxially engage guiding catheter.We report a case an 88-year-old woman with non-ST segment elevation myocardial infarction, RCA origin. Using either Judkins-Left catheter or Amplatz-Left was difficult ostium tortuosity. Thus, we used steam deform catheter, but back-up support insufficient deliver stent.We GuideLiner®, novel pediatric rapid...