A5071366565- Atherosclerosis and Cardiovascular Diseases
- Cardiac Imaging and Diagnostics
- Lipoproteins and Cardiovascular Health
- Atrial Fibrillation Management and Outcomes
- Adipokines, Inflammation, and Metabolic Diseases
- Acute Myocardial Infarction Research
- Mitochondrial Function and Pathology
- Cardiac Arrhythmias and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Disease and Adiposity
- Cardiovascular Function and Risk Factors
- Coronary Interventions and Diagnostics
- Cardiac electrophysiology and arrhythmias
- Protease and Inhibitor Mechanisms
- Tea Polyphenols and Effects
- Aortic Thrombus and Embolism
- Bone and Dental Protein Studies
- Cardiovascular Health and Disease Prevention
- Cardiomyopathy and Myosin Studies
- Reproductive tract infections research
- Cancer, Lipids, and Metabolism
- Aortic aneurysm repair treatments
- Heme Oxygenase-1 and Carbon Monoxide
- Heart Failure Treatment and Management
- Hormonal Regulation and Hypertension
Tokyo Medical Center
2016-2025
National Hospital Organization
2015-2024
Boehringer Ingelheim (Germany)
2021
Ochanomizu University
2005-2018
Toyo University
2016
Utsunomiya University
2016
National Defense Medical College
2000-2006
Icahn School of Medicine at Mount Sinai
2006
Heart Life Hospital
2006
College Station Medical Center
2005-2006
Several studies have demonstrated that the daily intakes of soy foods were associated with a reduced cardiovascular risk. The aim our study was to investigate inhibitory effect black soybeans on low density lipoprotein (LDL) oxidation in comparison yellow soybeans. extract from soybean had longer LDL lag time than (205 +/- 16 and 65 3 min, respectively). When both divided into seed coat mixture germ cotyledon, diluted solution prolonged significantly more original coat. On other hand,...
Early prediction of prognosis after out-of-hospital cardiac arrest (OHCA) remains difficult. High blood lactate or low pH levels may be associated with poor in OHCA patients, but these associations remain controversial. We compared and patients transferred to our hospital measure their prognostic performance.We investigated the between on admission neurological outcomes 372 who had a return spontaneous circulation.Of 31 favorable outcome. Blood were lower outcome than those an unfavorable...
Background Obesity is associated with advanced cardiovascular disease. However, some studies have reported the "obesity paradox" after percutaneous coronary intervention (PCI). The relationship between body mass index (BMI) and clinical outcomes PCI has not been thoroughly investigated, especially in Asian populations. Methods We studied 10,142 patients who underwent at 15 Japanese hospitals participating JCD-KICS registry from September 2008 to April 2013. Patients were divided into four...
Atherosclerotic diseases, like coronary artery disease (CAD), are recognized to be associated with oxidative stress and inflammation. Sestrin2 is a stress-inducible protein that has anti-oxidant anti-inflammatory properties. We previously reported plasma sestrin2 levels were high in patients CAD. However, no study shown their prognostic value investigated the association between major adverse cardiovascular events (MACE) (cardiovascular death, myocardial infarction, unstable angina,...
Several Japanese cohort studies have reported that the intakes of plant foods, such as vegetables, fruits, seaweed, and soy products, are inversely associated with coronary artery disease (CAD). However, results these been inconsistent. We investigated association between CAD foods in 802 patients undergoing angiography. The products were determined by 3 categories (<3, 3–4, >4 times/wk). was found 511 patients, whom 173 had myocardial infarction (MI). Patients higher vegetable fruit a...
<h3>Importance</h3> The clinical characteristics and outcomes of women men with atrial fibrillation (AF) are reported to be different. However, whether sex-related differences extend patients' symptom burden perceived quality life (QOL) or the management pattern AF has been rarely studied, particularly in Asian countries. <h3>Objective</h3> To assess symptoms, treatment, QOL between Japanese female male patients AF. <h3>Design, Setting, Participants</h3> Retrospective cohort study using data...
A Microvolt-1evel T-wave alternans (alternating morphology from beat to beat) during atrial pacing and exercise may predict ventricular tachycardia (VT) fibrillation (VF) in ischemic heart disease. We tested whether such could identify high-risk patients with hypertrophic cardiomyopathy (HCM). studied 14 HCM 9 normal control subjects for using the CH2000 system 7 multisegment electrodes a Frank orthogonal (XYZ) configuration. Bicycle ergometer was used increase rate (HR) 95-110 beats/min....
Objective: Green tea was shown to inhibit LDL oxidation, platelet aggregation, and matrix metalloproteinases (MMPs) activities in vitro. We tried elucidate whether or not green consumption may have these effects vivo, which be protective against atherosclerotic disease.Methods: measured serum malondialdehyde-modified (MDA-LDL) concentrations urine 8-epi-prostaglandin (PG) F2α 22 healthy male nonsmokers. They drank 7 cups/day of water for 2 weeks the next weeks. Regarding plasma thromboxane...
Interstitial collagen, especially type I, is a major component of atherosclerotic plaques and the matrix metalloproteinases (MMP) 1, 8 13 can initiate collagen breakdown. MMP-8 degrades I preferentially more potently than MMP-1 or MMP-13. Although was thought to be produced only by neutrophils, it recently reported also endothelial cells, smooth muscle cells macrophages in plaques.Plasma concentrations were measured 250 patients undergoing coronary angiography for artery disease (CAD: >50%...
Aim: Resistin is an adipocytokine that may link inflammation and atherosclerosis.We studied the associations of resistin levels with cardiovascular events restenosis.Methods: We measured pre-procedural serum in 140 patients coronary artery disease undergoing elective percutaneous intervention (PCI), whom 97 had a stent. Restenosis was defined as > 50% stenosis at follow-up angiography. Patients were followed for 3 years major adverse (MACE).Results: At 8±6 months after PCI, reangiography...
It is unclear whether there are differences in the clinical factors between atrial fibrillation (AF) recurrence and adverse events (AEs), including stroke/transient ischemic attack (TIA), major bleeding, death, after AF ablation.