A5003428240- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiovascular Function and Risk Factors
- ECG Monitoring and Analysis
- Heart Rate Variability and Autonomic Control
- Cardiovascular and exercise physiology
- Heart Failure Treatment and Management
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Acute Ischemic Stroke Management
- Blood Pressure and Hypertension Studies
- Coronary Interventions and Diagnostics
- Health Systems, Economic Evaluations, Quality of Life
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Effects of Exercise
- Chronic Kidney Disease and Diabetes
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Syncope and Autonomic Disorders
- Cardiomyopathy and Myosin Studies
- Pharmaceutical Practices and Patient Outcomes
- Cardiac Arrest and Resuscitation
- Neurological Disorders and Treatments
- Acute Kidney Injury Research
Cardiovascular Institute Hospital
2016-2025
Meijo University
2024
Yamagata University
2021
Toho University
2005-2020
Otsuka (United Kingdom)
2016
Cardiovascular Institute of the South
2010-2014
Innovation Cluster (Canada)
2005
Toho University Omori Medical Center
2005
Gunma University
1993-1994
Aims Non-linear models by machine learning may identify different risk factors with weighting in comparison to conventional linear models. Methods and results The analyses were performed 15,933 patients included the Shinken Database (SD) 2004–2014 (n = 22,022) for whom baseline data of blood sampling ultrasound cardiogram follow-up at 2 years available. Using non-linear software, 118 their all-cause mortality, heart failure (HF), acute coronary syndrome (ACS), ischemic stroke (IS),...
Although various kinds of cardiovascular risk factors have been reported to be associated with atrial fibrillation (AF), the relationship between serum uric acid level and AF has not fully examined.Data were collected from a single hospital-based cohort in Shinken Database 2004-2008 (n=11,123), consisted for 7,155 patients. The association prevalence was evaluated on logistic regression. Uric significantly increased crude both men women (both, P<0.001). odds ratio (OR) 95% confidence...
Background:Trends of oral anticoagulant (OAC) prescription and incidence thromboembolism (TE) and/or major bleeding (MB) in patients with non-valvular atrial fibrillation (NVAF) Japan are still unclear.Methods Results:We used data from Shinken Database 2004–2012, which included all new attending the Cardiovascular Institute between June 2004 March 2013. Of them, 2,434 were diagnosed NVAF. Patients divided into 3 time periods according to year initial visit: 2004–2006 (n=681), 2007–2009...
The efficacy of artificial intelligence (AI)-enhanced electrocardiography (ECG) for detecting hypertrophic cardiomyopathy (HCM) and its dilated phase (dHCM) has been developed, though specific ECG characteristics associated with these conditions remain insufficiently characterized. This retrospective study included 19,170 patients, 140 HCM or dHCM cases, from the Shinken Database (2010-2017). cases (HCM-total) were categorized into basal-only (HCM-basal, n = 75), apical involvement...
There is increasing evidence that 12-lead electrocardiograms (ECG) can be used to predict biological age, which associated with cardiovascular events. However, the utility of artificial intelligence (AI)-predicted age using ECGs remains unclear.Using a single-center database, we developed an AI-enabled ECG 17 042 sinus rhythm (SR-ECG) chronological (CA) convolutional neural network yields AI-predicted age. Using 5-fold cross validation method, deriving from test dataset was yielded for all...
Japan has become an aging society, resulting in increased prevalence of coronary artery disease. However, clinical outcomes elderly Japanese patients after percutaneous intervention (PCI) remain unclear. Of the 15,227 Shinken Database, a single-hospital-based cohort new patients, 1,214 who underwent PCI, was evaluated to determine differences between (≥75 years) (n = 260) and non-elderly (<75 954) patients. A major adverse cardiac event (MACE) defined as composite end point, including...
Repeated hospitalization due to acute decompensated heart failure (HF) is a pandemic health problem in Japan. However, it difficult predict rehospitalization after discharge for HF. We used single hospital-based cohort from the Shinken Database 2004–2012, comprising all new patients (n = 19,994) who visited Cardiovascular Institute Hospital. A total of 282 discharged their first HF admission were included analysis. The median follow-up period was 908 ± 865 days. Of these patients, worsening...
It is unclear whether there are differences in the clinical factors between atrial fibrillation (AF) recurrence and adverse events (AEs), including stroke/transient ischemic attack (TIA), major bleeding, death, after AF ablation.
Abstract Background There is a well-established relationship between 12-lead electrocardiogram (ECG) and age mortality. Furthermore, there increasing evidence that ECG can be used to predict biological age. However, the utility of from for predicting mortality remains unclear. Methods This was single-center cohort study cardiology specialized hospital. A total 19,170 patients registered in this February 2010 March 2018. analyzed final 12,837 after excluding those with structural heart...
Abstract Background Premature ventricular contractions (PVCs) and nonsustained tachycardia (NSVT) are common arrhythmias in cardiovascular clinical settings. However, the significance of PVCs NSVT absence structural heart disease has not yet been fully elucidated. This study aimed to evaluate association between PVCs, NSVT, outcomes. Methods A population 26,117 patients was drawn from Shinken Database established June 2004. We enrolled 6332 without who underwent 24‐h Holter monitoring were...
Background: This study investigated the progression of paroxysmal atrial fibrillation (AF) to persistent form in Japanese asymptomatic AF patients. Methods and Results: Data were derived from a single hospital-based cohort Shinken Database 2004–2012 (n=19,994), which 1,176 patients diagnosed as having AF. occurred 115 (6.0%/year) during mean follow-up period (1,213±905 days). Although who at initial visit (n=468) had low-risk profile compared with symptomatic patients, they greater...
Background: The distribution of activated partial thromboplastin time (APTT) in nonvalvular atrial fibrillation (NVAF) patients under dabigatran therapy remains to be clarified. Methods and Results: study population was 196 NVAF who were treated with 2011 (126 220mg/day). APTT values showed a wide among the patients, especially those reduced dose, seemed show high value even without contraindications. Conclusions: We found treatment. High might help screen for bleeding risks dabigatran, but...
Statins reduce cardiovascular morbidity and mortality from coronary artery disease (CAD). However, the effects of statin therapy in patients with CAD chronic kidney (CKD) remain unclear. Within a single hospital-based cohort Shinken Database 2004-2010 comprising all (n = 15,227) who visited Cardiovascular Institute, we followed CKD after percutaneous intervention (PCI). A major adverse cerebrovascular event (MACCE) was defined by composite end points, including death, myocardial infarction,...
The characteristics and prognosis of patients with first-detected atrial fibrillation (AF) in Japan remain unclear.First-detected AF without structural heart disease (n=289) were reviewed regard to 2 symptom classifications (CCS-SAF EHRA). In both classifications, asymptomatic comprised ≈40% the patients, most symptomatic class (≈6%) had peculiar poor prognosis. other classes, symptoms affected treatment strategy a significant difference patients' backgrounds prognosis.This is first report...
Revascularization of an initially non-target site due to its progression as a new culprit lesion has emerged therapeutic target coronary artery disease (CAD) in the era drug-eluting stents. Using Shinken database, single-hospital-based cohort, we aimed clarify incidence and prognostic factors for previously non-significant portions after prior percutaneous intervention (PCI) Japanese CAD patients. We selected from database cohort patients (n = 15227) who visited Cardiovascular Institute...