A5016261053- Asymmetric Synthesis and Catalysis
- Asymmetric Hydrogenation and Catalysis
- Catalytic C–H Functionalization Methods
- Oxidative Organic Chemistry Reactions
- Chemical Synthesis and Analysis
- Organoboron and organosilicon chemistry
- Obstructive Sleep Apnea Research
- Chemical Reactions and Isotopes
- Carbohydrate Chemistry and Synthesis
- Click Chemistry and Applications
- Biopolymer Synthesis and Applications
- Innovative Microfluidic and Catalytic Techniques Innovation
- Quinazolinone synthesis and applications
- Synthetic Organic Chemistry Methods
- Advanced Computing and Algorithms
- Catalytic Cross-Coupling Reactions
- Sulfur-Based Synthesis Techniques
- Civil and Geotechnical Engineering Research
- Synthesis of Indole Derivatives
Wuhan University
2022-2024
Qingdao Center of Resource Chemistry and New Materials
2020
Qingdao Agricultural University
2020
Lanzhou Petrochemical Polytechnic
2006
Substituted six-membered cyclic hydrocarbons are common constituents of biologically active compounds. Although methods for the synthesis thermodynamically favored, disubstituted cyclohexanes well established, a reliable and modular protocol their stereoisomers is still elusive. Herein, we report general strategy with excellent kinetic stereocontrol from readily accessible substituted methylenecyclohexanes by implementation chain-walking catalysis. Mechanistically, initial introduction...
Chiral boronic esters are a class of versatile building blocks. We describe herein an asymmetric nickel-catalyzed borylative coupling terminal alkenes with nonactivated alkyl halides. The success this reaction is ascribed to the application chiral anionic bisoxazoline ligand. This study provides three-component strategy access α- and β-stereogenic from easily accessible starting materials. protocol characterized by mild conditions, wide substrate scope high regio- enantioselectivity. also...
Hydride transfer enabled the first success of regioselective dearomatization indoles in carbocyclic ring and pyrrole ring, which was induced by <italic>ortho</italic>-quinone methides vinylogous iminium intermediates, respectively.
The construction of five and six membered heterocycle fused spirooxindoles was achieved <italic>via</italic> the [4 + 1] formal 2] cycloadditions between our rationally designed four-membered synthons pyridinium methylides α-bromoacetophenones, respectively.
Structurally diverse amino acids and their ester derivatives were conveniently <italic>N</italic>,<italic>N</italic>′-dialkylated <italic>via</italic> TFE promoted cascade condensation/[1,5]-hydride transfer/cyclization for straightforward construction of tetrahydroquinazolines incorporating various acids.
Correction for ‘Hydride transfer enabled switchable dearomatization of indoles in the carbocyclic ring and pyrrole ring’ by Kang Duan <italic>et al.</italic>, <italic>Org. Chem. Front.</italic>, 2020, <bold>7</bold>, 2511–2517, DOI: 10.1039/D0QO00658K.