A5007119545- Health Systems, Economic Evaluations, Quality of Life
- Statistical Methods in Clinical Trials
- Patient-Provider Communication in Healthcare
- Multiple Myeloma Research and Treatments
- Economic and Environmental Valuation
- Erythropoietin and Anemia Treatment
- Acute Lymphoblastic Leukemia research
- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Migraine and Headache Studies
- Complementary and Alternative Medicine Studies
- Dermatology and Skin Diseases
- Psychosomatic Disorders and Their Treatments
- COVID-19 Impact on Reproduction
- Chronic Lymphocytic Leukemia Research
- Physical Activity and Health
- Iron Metabolism and Disorders
- Blood donation and transfusion practices
- Suicide and Self-Harm Studies
- Acute Kidney Injury Research
- Mobile Health and mHealth Applications
- Kawasaki Disease and Coronary Complications
- Protein Degradation and Inhibitors
- Dialysis and Renal Disease Management
- Chronic Myeloid Leukemia Treatments
EVRAZ (United Kingdom)
2020-2025
University of Louisville Hospital
2024
University of Tennessee Health Science Center
2022
Indiana University Hospital
2021
Indiana University – Purdue University Indianapolis
2021
AdventHealth Orlando
2020
More adjuvant treatment options are becoming available for hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) early breast cancer (EBC) based on results of clinical trials. This study quantified the importance different attributes EBC therapies to patients and benefit-risk tradeoffs were willing make. Women with HR+/HER2- completed an online discrete choice experiment (DCE) survey; design was informed by data, qualitative interviews (n = 40), pre-testing...
755 Background: The treatment landscape for la/mUC has evolved with multiple care options available. As new therapies are adopted, decision-making among physicians, patients, and their caregivers becomes more complex challenging. This study summarizes the existing literature on preferences of patients about aspects following a diagnosis la/mUC. Methods: A TLR English-language conference abstracts full-text manuscripts published from 2015 was conducted using Embase PubMed, to identify...
Objectives We aimed to quantify patient preferences for efficacy, safety and convenience features of atopic dermatitis (AD) treatments. Design setting Online discrete choice experiment survey. Participants Adults in the UK, France Spain who had used AD treatments during past 2 years. Primary secondary outcome measures Preferences attributes were analysed using a multinomial logit model. Willingness make trade-offs was expressed as maximum acceptable decrease (MAD) probability achieving...
Introduction Newer treatment options for relapsed/refractory multiple myeloma (RRMM) with efficacy and safety profiles that differ from traditional therapies have facilitated personalized management strategies to optimize patient outcomes. In the context of such management, understanding how characteristics influence patients’ preferences is essential. This study assessed RRMM attributes determined trade-offs between potential benefits, administration procedures, adverse effects. Methods...
Information about patient preferences for the treatment of anaemia associated with chronic kidney disease (CKD) is scarce. Hence, our aim was to examine how patients non-dialysis-dependent CKD valued attributes alternative hypothetical treatments. A discrete choice experiment (DCE) conducted in adult who reported a clinical diagnosis CKD-related anaemia. Treatment included mode and frequency administration, need iron supplementation, risk gastrointestinal side effects, major cardiovascular...
Research about the decision to participate in a clinical study has tended be limited single indications and focused on narrow sets of participant characteristics. This applied stated preference methods understand trial design attributes that most influence willingness how this varied with
With the expanding treatment landscape for asthma, process of identifying best-fit, individualized management options is becoming increasingly complicated. Understanding patients' preferences can inform shared decision-making between clinicians and patients.To examine adults with asthma therapeutic attributes determine how these vary among patients.We conducted an online discrete choice experiment survey in US asthma. Patient were analyzed using logit models. Factors affecting identified by...
Although several self-injectable preventive treatments for migraine have become available, they are not yet widely used. Thus, understanding patients' perceptions towards them is limited. This study aimed to inform the design of a preference-elicitation instrument, which being developed quantify treatment preferences people with migraine. We conducted qualitative involving nine in-person focus groups (three per country) in United States, Kingdom, and Germany. Participants were adults (n =...
The US National Asthma Education and Prevention Program updates Global Initiative for report encourage considering the patient perspective to improve asthma control. objective of present study was collect data about perceptions, experiences, concerns adult patients caregivers children with regarding rescue, maintenance, oral corticosteroid treatments.In-person focus groups were conducted in three cities across US. Participants also completed patient-reported outcome measures assessing...
Aim: We examined the preferences of adults with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) for benefits and risks tyrosine kinase inhibitors combined chemotherapy first-line treatment. Methods: In a discrete choice experiment, 201 patients chose between hypothetical treatment alternatives varied levels remission duration overall survival (OS), major cardiovascular (CV) events myelosuppression. Results: Although OS was most important attribute to Ph+ ALL, they...
Abstract Background Patients with follicular lymphoma (FL) often relapse or become refractory to treatment (R/R). While the R/R FL landscape evolves, little is known about priorities of patients and physicians. This discrete‐choice experiment (DCE) study assessed patients' physicians' preferences, trade‐offs they would be willing make between efficacy, tolerability, administration. Methods An online survey was conducted in US‐based (≥18 years) FL‐treating The DCE informed by a targeted...
Abstract Background and Aims Anaemia is a common complication of chronic kidney disease (CKD) that associated with fatigue, shortness breath, lethargy. CKD anaemia commonly treated oral or intravenous (IV) iron IV subcutaneous (SC) erythropoiesis-stimulating agents (ESAs). The objectives this study were to understand patients’ experiences their preferences related treatment. Method Qualitative 60-minute semi-structured interviews conducted ESA-treated adult patients anaemia, either...
Topic: 14. Myeloma and other monoclonal gammopathies - Clinical Background: The advent of novel treatment options for relapsed/refractory multiple myeloma (RRMM) with differing administration (admin), efficacy/safety profiles, necessitates an understanding the relative importance attributes to patients (pts), trade-offs they are willing make when considering options. Aims: To explore heterogeneity in pt preferences RRMM treatment. Methods: Adults who had progressed on ≥2 lines therapy (LOT)...
To, Emily; Vilar, Jason; Andrews, Jessica; Louzon, Patricia; Thomas, Caitlin; Parikh, Amay Author Information