Interactions between species, particularly where one is likely to be a pathogen of the other, as well geographical distribution have been systematically extracted from various web-based, free-access sources, and assembled with accompanying evidence into single database. The database attempts answer questions such what are all pathogens host, hosts pathogen, countries was found, found in country. Two datasets were database, focussing on species interactions distribution, based published...

Novel pathogenic coronaviruses - such as SARS-CoV and probably SARS-CoV-2 arise by homologous recombination between co-infecting viruses in a single cell. Identifying possible sources of novel therefore requires identifying hosts multiple coronaviruses; however, most coronavirus-host interactions remain unknown. Here, deploying meta-ensemble similarity learners from three complementary perspectives (viral, mammalian network), we predict which mammals are coronaviruses. We that there...

Emerging infectious diseases arising from pathogen spillover mammals to humans constitute a substantial health threat. Tracing virus origin and predicting the most likely host species for future events are major objectives in One Health disciplines.We assessed patterns of sharing among large diversity mammals, including domestic species.Global.Current.Mammals associated viruses.We used network centrality analysis trait-based Bayesian hierarchical models explore mammals. We analysed global...

Life-history traits have been identified as major indicators of mammals' susceptibility and exposure to viruses due evolutionary constraints that link life-history speed with species’ ecology immunity. Nonetheless, it is unclear where along the fast-slow continuum mammalian lies greatest diversity host species. Consequently, patterns govern host–virus associations remain largely unknown. Here we analyse virome 1350 wild mammals detect characteristics drive species' compatibility different...

Abstract Modelling approaches aimed at identifying unknown hosts of zoonotic pathogens have the potential to make high‐impact contributions global strategies for risk surveillance. However, geographical and taxonomic biases in host–pathogen associations affect reliability models their predictions. Here, we propose a methodological framework mitigate effect data account uncertainty models' Our approach involves ‘pseudo‐negative’ species integrating sampling into modelling pipeline. We present...

This is the first UK small animal disease surveillance report from SAVSNET. Future reports will expand to other syndromes and diseases. As data are collected for longer, estimates of changes in burden become more refined, allowing targeted local perhaps national interventions. Anonymised can be accessed research purposes by contacting authors. SAVSNET welcomes feedback on this report.

Our knowledge of viral host ranges remains limited. Completing this picture by identifying unknown hosts known viruses is an important research aim that can help identify and mitigate zoonotic animal-disease risks, such as spill-over from animal reservoirs into human populations. To address knowledge-gap we apply a divide-and-conquer approach which separates viral, mammalian network features three unique perspectives, each predicting associations independently to enhance predictive power....

Diseases that spread to humans from animals, zoonoses, pose major threats human health. Identifying animal reservoirs of zoonoses and predicting future outbreaks are increasingly important health well-being economic stability, particularly where research resources limited. Here, we integrate complex networks machine learning approaches develop a new approach identifying reservoirs. An exhaustive dataset mammal–pathogen interactions was transformed into hosts linked via their shared...

Presentation for gastrointestinal (GI) disease comprised 2.2 per cent of cat, 3.2 dog and rabbit consultations between April 1, 2016 March 31, 2017 Diarrhoea vomiting without blood were the most frequently reported GI clinical signs (34.4 38.9 in cats 42.8 37.3 dogs, respectively) The mean percentage samples testing positive Salmonella dogs was double that (0.82 0.41 cent, from January 2011 to December In autumn associated with a greater proportion ‐positive sample submissions; no clear...

What are all the species of pathogen that affect our livestock? As 6 out every 10 human pathogens came from animals, with a good number livestock and pets, it seems likely majority emerge in future, which could threaten or devastate health, will come animals. Only years ago, first comprehensive list was compiled for humans; we still have no equivalent Here describe creation novel database, present outputs database demonstrate its value. The ENHanCEd Infectious Diseases (EID2) is open-access...

Citizens have a variety of ways to consult with their representatives about policy proposals, seeking justifications, objecting all or part it, making counter-proposal. For the first, representative needs only state justification. second, would want understand objections, which may involve asking some questions. third, citizen provide well formulated proposal that can then be critiqued from standpoint government's own proposal. At end such consultation, users will aired understood...

Mosquito-borne viruses have been estimated to cause over 100 million cases of human disease annually. Many methodologies developed help identify areas most at risk from transmission these viruses. However, generally, focus predominantly on the effects climate either vectors or pathogens they spread, and do not consider dynamic interaction between optimal conditions for both vector virus. Here, we use a new approach that considers complex interplay temperature virus transmission, mosquito...

Recent publications highlighting autochthonous Babesia canis infection in dogs from Essex that have not travelled outside the UK are a powerful reminder of potential for pathogen emergence new populations. Here authors use electronic health data collected two diagnostic laboratories and network 392 veterinary premises to describe canine cases levels concern January 2015 March 2016, activity ticks during December 2015-March 2016. In most areas UK, diagnosis this population was rare sporadic....

Presentation for respiratory disease comprised 1.7 per cent, 2.3 cent and 2.5 of canine, feline rabbit consultations, respectively, between January 2014 December 2015 Coughing was the most frequent sign reported in dogs (71.1 consultations); cats it sneezing (42.6 cent) Mean percentage samples testing positive calicivirus (FCV) 30.1 27.9 month with highest FCV‐positive both

Abstract Background Monkeypox is a zoonotic virus which persists in animal reservoirs and periodically spills over into humans, causing outbreaks. During the current 2022 outbreak, monkeypox has persisted via human-human transmission, across all major continents for longer than any previous record. This unprecedented spread creates potential to ‘spillback’ local susceptible populations. Persistent transmission amongst such animals raises prospect of becoming enzootic new regions. However,...

<title>Abstract</title> 1. Modelling approaches aimed at identifying currently unknown hosts of zoonotic diseases have the potential to make high-impact contributions global strategies for risk surveillance. However, geographical and taxonomic biases in host-pathogen associations might influence reliability models their predictions. 2. Here we propose a methodological framework mitigate effect host–pathogen data account uncertainty models’ Our approach involves “pseudo-negative” species...

In 2006, bluetongue (BT), a disease of ruminants, was introduced into northern Europe for the first time and more than two thousand farms across five countries were affected. 2007, BT affected 35,000 in France Germany alone. By contrast, UK outbreak beginning 2007 relatively small, with only 135 southeast England We use model to investigate effects three factors on scale outbreaks UK: (1) place introduction; (2) temperature; (3) animal movement restrictions. Our results suggest that could...