A5013263819- Zoonotic diseases and public health
- Animal Disease Management and Epidemiology
- Viral Infections and Vectors
- Vector-Borne Animal Diseases
- Prion Diseases and Protein Misfolding
- Climate Change and Health Impacts
- Metallurgy and Material Science
- Agriculture and Farm Safety
- Human-Animal Interaction Studies
- Mosquito-borne diseases and control
- COVID-19 epidemiological studies
- Viral gastroenteritis research and epidemiology
- Agriculture Sustainability and Environmental Impact
- Pharmaceutical and Antibiotic Environmental Impacts
- Data-Driven Disease Surveillance
- Trace Elements in Health
- Salmonella and Campylobacter epidemiology
- Rangeland Management and Livestock Ecology
- Yersinia bacterium, plague, ectoparasites research
- Antibiotic Resistance in Bacteria
- Antimicrobial Resistance in Staphylococcus
- Soil erosion and sediment transport
- Gut microbiota and health
- Mycobacterium research and diagnosis
- Microbial infections and disease research
University of Liverpool
2016-2025
Newcastle University
2023-2025
EcoHealth Alliance
2024
Society for Endocrinology
2019-2022
Health Protection Research Unit in Emerging and Zoonotic Infections at University of Liverpool
2016-2021
University of Pennsylvania Health System
2019
Glasgow Centre for Population Health
2017-2018
NIHR Southampton Biomedical Research Centre
2017
National Consortium for Zoonosis Research
2014
The Pirbright Institute
2006-2010
The Asian tiger mosquito ( Aedes albopictus ) is an invasive species that has the potential to transmit infectious diseases such as dengue and chikungunya fever. Using high-resolution observations regional climate model scenarios for future, we investigated suitability of Europe A. using both recent future conditions. results show southern France, northern Italy, coast Spain, eastern Adriatic Sea western Turkey were climatically suitable areas establishment during 1960–1980s. Over last two...
Abstract One Health recognises the interdependence between health of humans, animals, plants and environment. With increasing inclusion in multiple global strategies, workforce must be prepared to protect sustain well-being life on planet. In this paper, a review past currently accepted core competencies was conducted, with competence gaps identified. Here, Network for Ecohealth (NEOH) propose updated designed simplify what can complex area, grouping into three main areas of: Skills; Values...
Although the effects of antimicrobial resistance (AMR) are most obvious at clinical treatment failure, AMR evolution, transmission, and dispersal happen largely in environmental settings, for example within farms, waterways, livestock, wildlife. We argue that systems-thinking, One Health approaches crucial tackling AMR, by understanding predicting how anthropogenic activities interact subsystems, to drive emergence transmission. Innovative computational methods integrating big data streams...
Interactions between species, particularly where one is likely to be a pathogen of the other, as well geographical distribution have been systematically extracted from various web-based, free-access sources, and assembled with accompanying evidence into single database. The database attempts answer questions such what are all pathogens host, hosts pathogen, countries was found, found in country. Two datasets were database, focussing on species interactions distribution, based published...
Climate change is expected to threaten human health and well-being via its effects on climate-sensitive infectious diseases, potentially changing their spatial distributions, affecting annual/seasonal cycles, or altering disease incidence severity. sensitivity of pathogens a key indicator that diseases might respond climate change, but the proportion climate-sensitive, characteristics, are not known. The European domestic animal pathogens, characteristics associated with sensitivity, were...
COVID-19 has disrupted everyday life worldwide and is the first disease event since 1918 H1N1 Spanish influenza (flu) pandemic to demand an urgent global healthcare response. There been much debate on whether damage of due predominantly pathogen itself or our response it. We compare SARS-CoV-2 against three other major pandemics (1347 Black Death, 1520's new world smallpox outbreaks, Flu pandemic) over course 700 years unearth similarities differences in pathogen, social medical context,...
Several studies provide evidence of a link between vector-borne disease outbreaks and El Niño driven climate anomalies. Less investigated are the effects North Atlantic Oscillation (NAO). Here, we test its impact on outbreak occurrences 13 infectious diseases over Europe during last fifty years, controlling for potential bias due to increased surveillance detection. NAO variation statistically influenced occurrence eleven diseases. Seven were associated with winter positive phases in...
Understanding the global economic importance of farmed animals to society is essential as a baseline for decision making about future food systems. We estimated annual (market) value live and primary production outputs, e.g., meat, eggs, milk, from terrestrial aquatic animal The results suggest that total market ranges between 1.61 3.3 trillion USD (2018) expected be similar in absolute terms crop outputs (2.57 USD). cattle sector dominates animals. study highlights need consider other...
The housing of animals at night was investigated as a possible means protecting them from attack by Culicoides biting midges (Diptera: Ceratopogonidae), the vectors bluetongue. Light-trap catches were compared inside and outside animal housing, in presence absence cattle. A three-replicate, 4 × Latin square design used four farms Bala, north Wales, over 12 nights May June 2007, experiment repeated October. In two studies, respectively, >70 000 >4500 trapped, which 93% 86%, obsoletus group....
Antimicrobial resistance (AMR) is a critical health problem, with systemic antimicrobial therapy driving development of AMR across the host spectrum. This study compares longitudinal carriage, at multiple timepoints, faecal Escherichia coli in dogs undergoing routine treatment. Faecal samples (n = 457) from 127) were examined pretreatment, immediately after treatment and 1 month 3 months post-treatment one five antimicrobials. Isolates tested for susceptibility to range antimicrobials using...
Livestock provide nutritional and socio-economic security for marginalized populations in low middle-income countries. Poorly-informed decisions impact livestock husbandry outcomes, leading to poverty from disease, with repercussions on human health well-being. The Global Burden of Animal Diseases (GBADs) programme is working understand the impacts disease upon livelihoods welfare. This information can then be used by policy makers operating regionally, nationally making global decisions....
Summary. Mouse spermatozoa require micromolar concentrations of calcium for capacitation but millimolar levels to initiate an acrosome reaction. Sperm suspensions were capacitated by incubation 120 min in modified Tyrode's medium containing 90 μm-CaCl2 and then verapamil (0·5–50 μm) or nifedipine (0·1–100 nm), drugs shown inhibit voltage-sensitive channels other cell types, was added before the introduction 1·80 mm-CaCl2. Verapamil at 5–50 μm 1–100nm significantly inhibited...
Summary Culicoides midges (Diptera: Ceratopogonidae) are ubiquitous on farms in the United Kingdom ( UK ), but little research has explored their abundance, an important determinant of disease risk. Models to explain and predict variation abundance needed for effective targeting control methods against bluetongue virus BTV ) other ‐borne diseases. Although models have been attempted at national scale (e.g. Scotland), no investigations taken place a finer spatial scale. Midge abundances were...
Assessment of the relative impact diseases and pathogens is important for agencies other organizations charged with providing disease surveillance, management control. It also helps funders disease-related research to identify most areas investment. Decisions as which or target are often made using complex risk assessment approaches; however, these usually involve evaluating a large number hazards it rarely feasible conduct an in-depth appraisal each. Here we propose use H-index (or Hirsch...
Disease or pathogen risk prioritisations aid understanding of infectious agent impact within surveillance mitigation and biosecurity work, but take significant development. Previous work has shown the H-(Hirsch-)index as an alternative proxy. We present a weighted analysis describing for human health (human pathogens) well-being (domestic animal using objective, evidence-based, repeatable approach; H-index. This study established highest H-index European pathogens. Commonalities amongst...
So-called atypical scrapie was first identified in Great Britain (GB) 2002 following the introduction of wide-scale surveillance. In particular, abattoir and fallen stock surveys have been carried out GB since 2002, with a total 147 positives by end 2006. The results these provide data which to assess temporal trends prevalence sheep between Using surveys, (percentage samples positive) estimated. for all years combined, 0.09% (95% confidence interval (CI): 0.08%–0.11%) 0.07% CI:...