- Inflammatory mediators and NSAID effects
- Nanoparticle-Based Drug Delivery
- RNA Interference and Gene Delivery
- S100 Proteins and Annexins
- Pickering emulsions and particle stabilization
- Protease and Inhibitor Mechanisms
- Nanoplatforms for cancer theranostics
- Seaweed-derived Bioactive Compounds
- Immunotherapy and Immune Responses
- Polysaccharides Composition and Applications
- Infectious Diseases and Mycology
- Cancer Cells and Metastasis
- Immune cells in cancer
- Proteins in Food Systems
Universidade Federal do Paraná
2020-2024
Rega Institute for Medical Research
2017
KU Leuven
2017
Gelatinase B or matrix metalloproteinase-9 (MMP-9) (EC 3.4.24.35) is increased in inflammatory processes and cancer, associated with disease progression. In part, this due to MMP-9-mediated degradation of extracellular matrix, facilitating influx leukocytes into inflamed tissues invasion metastasis cancer cells. MMP-9 produced as proMMP-9 its propeptide subsequently removed by other proteases generate proteolytically active MMP-9. The significance pathologies triggered the development...