A5072423243- Electrospun Nanofibers in Biomedical Applications
- Nanoparticle-Based Drug Delivery
- Cellular Mechanics and Interactions
- RNA Interference and Gene Delivery
- 3D Printing in Biomedical Research
- Orthopaedic implants and arthroplasty
- Cancer Cells and Metastasis
- Bone Tissue Engineering Materials
- Microencapsulation and Drying Processes
- Bee Products Chemical Analysis
- Immunotherapy and Immune Responses
- Nanoparticles: synthesis and applications
- Silk-based biomaterials and applications
- Tissue Engineering and Regenerative Medicine
Universidade Federal do Paraná
2020-2024
The design of powerful in vitro cell culture platforms to support precision medicine can contribute predict therapeutic success cancer patients. Electrospun nanofibers applied mimic extracellular matrix and improve behavior. Here, we describe biocompatible blended polyvinyl-alcohol (PVA)/gum arabic (GA) (ECM)-like for cultures capable delivering nanocomposite desired biomedical application. Therefore, PVA/GA ECM-like electrospun were developed characterized. Heat treatment was used crosslink...
Abstract The present review provides a comprehensive overview of the current state in vitro cancer studies, focusing on recent advancements and ongoing cell culture models analyses techniques. Cancer cells grow complex dynamic environment, interacting with various cellular components, such as stromal cells, cancer‐associated fibroblasts, immune extracellular matrix (ECM). ECM structural support unique characteristics essential for tumorigenesis. Accurately modeling this intricate tumor...
Abstract Zein, a corn‐derived protein, has variety of applications ranging from drug delivery to tissue engineering and wound healing. This work aims develop biocompatible scaffold for dermal based on thermally annealed electrospun propolis‐loaded zein nanofibers. Pristine fibers' biocompatibility is determined in vitro. Next, propolis Melipona quadrifasciata added the fibers at different concentrations (5% 25%), scaffolds are studied. The physicochemical properties zein/propolis precursor...