A5075722440- Cancer, Hypoxia, and Metabolism
- Lipid metabolism and biosynthesis
- Lung Cancer Research Studies
- Ubiquitin and proteasome pathways
- Cancer-related Molecular Pathways
- Lung Cancer Treatments and Mutations
- Hippo pathway signaling and YAP/TAZ
- Lung Cancer Diagnosis and Treatment
- Soft tissue tumor case studies
- Gastrointestinal disorders and treatments
- Gastrointestinal Tumor Research and Treatment
Fujian Medical University
2018-2023
Second Affiliated Hospital of Fujian Medical University
2018-2023
Yes-associated protein (YAP), a key player of the Hippo pathway, has been identified to have more and important roles in tumorigenesis may be an biomarker for cancer therapy. YAP is bladder cell migration, metastasis, drug resistance; however, its function stem cells remains unknown.The aim this work was examine expression role cells.We that level significantly enriched compared noncancer population. Moreover, effect on self-renewal examined by siRNA silencing approach. In addition, we...
EGISTs originating outside the gastrointestinal tract share some similarities with GISTs regarding their immunohistochemical features including positive expression of CD117 and CD34. The majority carry activating mutations C-KIT or PDGFRA genes. However, there is no precedent in literature where two occur one case to date. We describe herein, a 52-year-old female who presented as mesenteric pelvic regions masses showing immunoreactivity for CD117, DOG-1, Mutation analysis identified that...
Background: The physical tolerance in the advanced non-small cell lung cancer (NSCLC) patient often deteriorates, with a limited effective rate of third-line treatment. This study retrospectively analyzed efficacy and safety etoposide soft capsules combined anlotinib treatment NSCLC. Methods: A retrospective was conducted on 46 patients NSCLC who had failed second-line Progression-free survival (PFS) served as an endpoint. Kaplan-Meier curves were applied to evaluate short-term patients....