- Bariatric Surgery and Outcomes
- Nutrition and Health in Aging
- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Multiple and Secondary Primary Cancers
- Colorectal and Anal Carcinomas
- Clinical Nutrition and Gastroenterology
- Metastasis and carcinoma case studies
- Colorectal Cancer Treatments and Studies
- Esophageal and GI Pathology
- Body Contouring and Surgery
- Cancer Diagnosis and Treatment
- Genetic factors in colorectal cancer
- Diverticular Disease and Complications
- Neuroendocrine Tumor Research Advances
- Body Composition Measurement Techniques
- Cardiovascular Disease and Adiposity
- Abdominal Surgery and Complications
- Urinary and Genital Oncology Studies
- Cancer Treatment and Pharmacology
- Oral and Maxillofacial Pathology
- Autoimmune and Inflammatory Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Protein Tyrosine Phosphatases
- Obesity and Health Practices
University of Siena
2009-2024
Ospedale Santa Maria alle Scotte
2019-2021
Azienda Ospedaliera Universitaria Senese
2009-2018
Ospedale Santa Maria
2008
Bariatric surgery (BS) is the most effective treatment strategy for obesity. Nevertheless, a subset of patients does not reach successful weight loss or experience long-term regain. Conflicting evidence exists regarding predictors BS outcomes. We aimed to define early factors linked 3 year unsuccessful in order promote tailored close follow-up. enrolled 443 who underwent from January 2014 December 2018 with An outcome was defined as percentage total (%TWL) < 20. compared characteristics...
Previous results suggest that GEM affects 5-fluorouracil (5-FU) metabolism and pharmacokinetics in cancer patients, while combined with oxaliplatin, levo-folinic acid, 5-FU (GOLF regimen), at doses achievable determines high cytotoxic proapoptotic antitumour activity colon cells vitro. On these bases we designed a phase I–II clinical trial testing the GOLF regimen patients metastatic colorectal carcinoma, who had received least prior line of chemotherapy. In total, 29 (20 males nine females)...
Introduction Bioelectrical impedance analysis (BIA) is the most used tool in clinical practice to evaluate body composition patients with obesity. The skeletal muscle index (SMI) defined by BIA has been proposed for identification of sarcopenia, but there are currently no univocal cutoffs this condition. In study, we aimed: 1) determine prevalence sarcopenia severe obesity using current SMI; 2) define new specific cutoffs; 3) validate and 4) re-determine sarcopenia. Methods A total 300...
Abstract A single nucleotide polymorphism in the Type 2 deiodinase (DIO2) gene (p.Thr92Ala) was found to be associated with hypertension, type diabetes mellitus (T2DM), insulin resistance, and body mass index (BMI). We retrospectively evaluated 182 patients assess whether DIO2 p.Thr92Ala severe obesity response bariatric surgery. Genomic DNA extracted from peripheral blood leukocytes before Glycemic control parameters, cardiometabolic risk biomarkers (waist circumference, lipid assessment...
Metastatic involvement of the upper gastrointestinal tract from breast cancer has been reported in autopsy series as occurring more than 15% patients, usually associated with extensive systemic spread; clinical manifestations such metastases have described less 1% cases. Lobular infiltrating carcinoma seems to a different metastatic pattern ductal type, an apparent predilection for tract. presentation isolated intestinal obstruction without other signs spread is extremely rare. We present...
Although colonic diverticulum is a common disease, affecting about 35% of patients above the age 60, giant sigmoid an uncommon variant which only relatively few cases have been described in literature. We report on our experience with patient affected by who was treated diverticulectomy. Resection safe surgical procedure, provided that colon section close to lesion presents no sign flogosis or diverticula; addition, recurrences are not reported after 6-year follow-up.