- Hepatocellular Carcinoma Treatment and Prognosis
- Bariatric Surgery and Outcomes
- Liver Disease Diagnosis and Treatment
- Colorectal Cancer Surgical Treatments
- Gallbladder and Bile Duct Disorders
- Hepatitis B Virus Studies
- Minimally Invasive Surgical Techniques
- Pancreatic and Hepatic Oncology Research
- Cardiac, Anesthesia and Surgical Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Intestinal Malrotation and Obstruction Disorders
- Body Contouring and Surgery
- Appendicitis Diagnosis and Management
- Diverticular Disease and Complications
- Hepatitis C virus research
- Inflammatory Bowel Disease
- Gastrointestinal Tumor Research and Treatment
- Liver Disease and Transplantation
- Gastrointestinal disorders and treatments
- Anorectal Disease Treatments and Outcomes
- Pancreatitis Pathology and Treatment
- Gastric Cancer Management and Outcomes
- Microscopic Colitis
- Hernia repair and management
- Colorectal Cancer Screening and Detection
University of Messina
2016-2025
University of Cagliari
2025
Azienda Ospedaliera Universitaria Policlinico "G. Martino"
2016-2024
Carlo Forlanini Hospital
2023
Federico II University Hospital
2023
Collaborative Group (United States)
2021-2023
IRCCS San Camillo Hospital
2021
University of Rome Tor Vergata
2021
Istituto Ortopedico Gaetano Pini
2021
Magna Graecia University
2020
Abstract As limited information is available regarding the distribution and trafficking of NK cells among solid organs, we have analyzed a wide array tissues derived from different human compartments. were widely distributed in most tissues, although their amount varied significantly depending on tissue/organ analyzed. Interestingly, appeared to be subset specific, as some preferentially populated by CD56brightperforinlow cells, with others CD56dimperforinhigh cytotoxic counterpart....
To assess a new bloodless technique using radiofrequency energy for segmental liver resection of hepatic tumors.Liver remains formidable surgical procedure; safe performance requires high level training and skill. Intraoperative blood loss during major concern because it is associated with higher rate postoperative complications shorter long-term survival.From January 2000 to June 2001, 15 patients various tumors were operated on remove the tumor in its entirety. Radiofrequency was applied...
Abstract Background & Aims Hepatitis B virus ( HBV ) DNA integration in the host genome is a major mechanism responsible for etiopathogenetic role exerted by hepatocellular carcinoma HCC development. Extensive analyses evaluating viral surface antigen HB sAg) negative patients with occult infection OBI have not yet been performed. The aim of this study was to investigate and characterize tissues from patients. Methods Tumour extracts 69 (49 sAg‐negative diagnosed detection tumour...
BackgroundInsulin resistance in visceral adipose tissue (VAT), skeletal muscle and liver is a prominent feature of most patients with obesity. How this association arises remains poorly understood. The objective study was to demonstrate that the decrease insulin receptor (INSR) expression signaling VAT from obese individuals an early molecular manifestation might play crucial role cascade events leading systemic resistance.MethodsTo clarify INSR dysfunction obesity, we first measured samples...
Since its first documentation, a novel coronavirus (SARS-CoV-2) infection has emerged worldwide, with the consequent declaration of pandemic disease (COVID-19). Severe forms acute respiratory failure can develop. In addition, SARS-CoV-2 may affect organs other than lung, such as liver, frequent onset late cholestasis. We here report histological findings COVID-19 patient, affected by tardive complication ischemic and gangrenous cholecystitis perforated relaxed gallbladder needing urgent...
Efficacy and safety of OAGB/MGB (one anastomosis/mini gastric bypass) have been well documented both as primary revisional procedures. However, even after OAGB/MGB, surgery is unavoidable in patients with surgical complications or insufficient weight loss.A questionnaire asking for the total number demographics OAGB/MGBs performed between January 2006 July 2020 was e-mailed to all S.I.C. OB centres excellence (annual caseload > 100; 5-year follow-up 50%). Each bariatric centre asked provide...
Abstract Hepatitis B virus (HBV) may integrate into the genome of infected cells and contribute to hepatocarcinogenesis. However, role HBV integration in hepatocellular carcinoma (HCC) development remains unclear. In this study, we apply a high-throughput sequencing approach that allows sensitive identification sites enumeration clones. We identify 3339 paired tumour non-tumour tissue samples from 7 patients with HCC. detect 2107 clonally expanded integrations (1817 290 tissues), significant...
Background The Coronavirus 2019 (COVID-19) pandemic has favored the growth of telemedicine systems and in this context idea Metaverse was born developed. A 3D reality which people can interact with each other through digital reproductions themselves. already been tested numerous medical fields due to its ability combine visual auditory information tactile sensations. purpose study is highlight potential also be used as a telementoring place where skills knowledge surgeons from all over world...
// Antonino Agrusa 1 , Giorgio Romano Giuseppe Navarra 2 Giovanni Conzo 3 Gianni Pantuso 4 Di Buono Roberto Citarrella 5 Massimo Galia 6 Attilio Lo Monte Gaspare Cucinella 7 and Gulotta Department of General Surgery, Urgency Organ Transplantation, University Palermo, Italy Human Pathology Hospital Messina, Anesthesiologic, Surgical Emergency Sciences, Division Oncologic School Medicine, Second Naples, Surgery Oncology, Experimental Biomedicine Clinical Neurosciences, Section Radiology -...
Enhanced recovery after bariatric surgery (ERABS) is an approach developed to improve outcomes in obese surgical patients. Unfortunately, it not evenly implemented Italy. The Italian Society for the Surgery of Obesity and Metabolic Diseases Anesthesia, Analgesia, Resuscitation Intensive Care joined drafting official statement on ERABS.To assess effectiveness safety ERABS develop evidence-based recommendations with regard pre-, intra-, post-operative care patients undergoing ERABS, a...
A prospective randomized comparison of three-dimensional (3D) versus two-dimensional (2D) imaging during elective laparoscopic cholecystectomy (LC), both performed separately by an advanced surgeon and a experienced in open surgical procedures but novice at procedures, was designed to address the issue whether 3D systems offer real operative time advantages this procedure.Eighty patients were day surgery random computer-generated allocation list receive either or 2D high-definition system LC...
Abstract Background This study aimed to assess the best achievable outcomes in laparoscopic liver resection (LLR) after risk adjustment based on surgical technical difficulty using a national registry. Methods LLRs registered Italian Group of Minimally Invasive Liver Surgery registry from November 2014 March 2018 were considered. Benchmarks calculated according Achievable Benchmark Care (ABC™). at each centre divided into three clusters (groups I, II and III) Kawaguchi classification. ABCs...