A5003117162- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Hepatocellular Carcinoma Treatment and Prognosis
- Organ Donation and Transplantation
- Liver Disease Diagnosis and Treatment
- Gallbladder and Bile Duct Disorders
- Pancreatic and Hepatic Oncology Research
- Renal Transplantation Outcomes and Treatments
- Bone health and treatments
- Bone and Joint Diseases
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Transplantation: Methods and Outcomes
- Pancreatitis Pathology and Treatment
- Periodontal Regeneration and Treatments
- Minimally Invasive Surgical Techniques
- Hepatitis C virus research
- Colorectal Cancer Treatments and Studies
- Renal and Vascular Pathologies
- Congenital Anomalies and Fetal Surgery
- Cancer Diagnosis and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Genetic and Kidney Cyst Diseases
- Hernia repair and management
- Bone Tumor Diagnosis and Treatments
- Oral health in cancer treatment
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2014-2025
Azienda Socio Sanitaria Territoriale Lariana
2018-2021
Ospedale Maggiore
2015-2019
University of Pavia
2016-2017
University of Milano-Bicocca
2016-2017
Creative Research Enterprises (United States)
2017
University of Pisa
2006-2016
Policlinico San Matteo Fondazione
2016
Istituti di Ricovero e Cura a Carattere Scientifico
2016
Development Fund
2016
The role of donation after cardiac death (DCD) in expanding the donor pool is mainly limited by incidence primary nonfunction (PNF) and ischemia-related complications. Even greater concern exists toward uncontrolled DCD, which represents largest potential DCD donors. We recently started first Italian series liver transplantation, using normothermic regional perfusion (NRP) 6 donors 1 controlled case to deal with legally required no-touch period 20 minutes. examined our 7 cases for PNF, early...
Expansion of donor acceptance criteria for liver transplant increased the risk early allograft failure (EAF), and although EAF prediction is pivotal to optimize outcomes, there no consensus on specific indicators or timing evaluate EAF. Recently, Liver Graft Assessment Following Transplantation (L-GrAFT) algorithm, based aspartate transaminase, bilirubin, platelet, international normalized ratio kinetics, was developed from a single-center database gathered 2002 2015.To develop validate...
Donation after circulatory death (DCD) in Italy constitutes a relatively unique population because of the requirement no-touch period 20 minutes. The first aim this study was to compare liver transplantations from donors who were maintained on normothermic regional perfusion and suffered extended warm ischemia (DCD group, n = 20) with those extracorporeal membrane oxygenation (ECMO) succumbed brain (ECMO 17) standard (donation [DBD] 52). Second, we conducted an explorative analysis DCD group...
To determine whether non-surgical periodontal treatment (PT) would exert, in subjects with generalized chronic periodontitis (GCP), some beneficial effect on renal function as indicated by surrogate measures of the glomerular filtration rate (GFR).Twenty GCP systemically healthy were treated PT. Serum samples collected at baseline and 1 day, 7, 30, 90 180 days after treatment. GFR was evaluated using cystatin C, a serum marker modification diet disease (MDRD), an equation involving...
The use of machine perfusion (MP) in liver transplantation (LT) is spreading worldwide. However, its efficacy has not been demonstrated, and proper clinical far to go be widely implemented. Società Italiana Trapianti d'Organo (SITO) promoted the development an evidence-based position paper. A 3-step approach adopted develop this First, SITO appointed a chair cochair who then assembled working group with specific experience MP LT. Guideline Development Group framed questions into patient,...
Abstract Background This study aimed to assess the best achievable outcomes in laparoscopic liver resection (LLR) after risk adjustment based on surgical technical difficulty using a national registry. Methods LLRs registered Italian Group of Minimally Invasive Liver Surgery registry from November 2014 March 2018 were considered. Benchmarks calculated according Achievable Benchmark Care (ABC™). at each centre divided into three clusters (groups I, II and III) Kawaguchi classification. ABCs...
599 Background: Immunosuppression, the key post-transplant therapy to prevent organ rejection, is associated with an increased cancer risk. Kidney transplantation most frequent solid transplant, renal cell carcinoma (RCC) being common urologic in kidney transplant recipients (KTR). While numerous retrospective studies address RCC onset KTR, they often have limitations, including small sample size, case series design, and lack of annotation regarding pathological features immunosuppressive...
The UICC/AJCC TNM staging system classifies lymph nodes as N0 and N1 in pancreatic cancer. Aim of the study is to determine whether number examine nodes, nodal ratio (NR) logarithm odds positive (LODDS) may better stratify prognosis patients undergoing pancreatectomy combined with venous resection for cancer involvement. A multicenter database 303 9 Italian referral centers was analyzed. prognostic impact retrieved examined NR, LODDS analyzed compared ROC curves analysis, Pearson test,...
Despite gaining wide consensus in the management of hepatocellular carcinoma (HCC), minimally invasive liver surgery (MILS) has been poorly investigated for its role setting salvage transplantation (SLT). A multicenter retrospective analysis was carried out 6 Italian centers on 211 patients with HCC who were initially resected open (n = 167) versus MILS 44) and eventually wait-listed SLT. The secondary endpoint identification risk factors posttransplant death tumor recurrence. enrolled...
Background: Bisphosphonate (BP)-related osteonecrosis of the jaw (ONJ) is an unpredictable, debilitating adverse effect. Recently, genetic polymorphisms have arisen as promising tools to identify patients with a higher risk drug-related events. Aim: We aimed examine association between aromatase polymorphism g.132810C>T, and estrogen receptor g.156705T>C g.156751A>G, BP-related ONJ. Methods: Eighty-three subjects were included in study. A clinical radiological examination was conducted on...
Abstract Aim: To determine if the adjunctive use of intra‐muscular neridronate (NE) during non‐surgical periodontal treatment (PT) provides, in patients with generalized chronic periodontitis (GCP), benefits as compared PT alone 3 months after completion a 3‐month NE therapy. Material and Methods: Sixty GCP healthy were randomly assigned to control (CG) or test group (TG). CG received only. Thirty subjects TG also (12.5 mg an i.m. injection/week for months). Clinical parameters evaluated at...