Amedeo Carraro

ORCID: 0000-0001-6449-4597
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About
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Research Areas
  • Organ Transplantation Techniques and Outcomes
  • Liver Disease and Transplantation
  • Liver Disease Diagnosis and Treatment
  • Renal Transplantation Outcomes and Treatments
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Liver physiology and pathology
  • Transplantation: Methods and Outcomes
  • Polyomavirus and related diseases
  • Tissue Engineering and Regenerative Medicine
  • Esophageal Cancer Research and Treatment
  • 3D Printing in Biomedical Research
  • Organ Donation and Transplantation
  • Viral-associated cancers and disorders
  • Hepatitis C virus research
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • PI3K/AKT/mTOR signaling in cancer
  • Hepatitis B Virus Studies
  • Mesenchymal stem cell research
  • Gallbladder and Bile Duct Disorders
  • Cytomegalovirus and herpesvirus research
  • Appendicitis Diagnosis and Management
  • Chronic Kidney Disease and Diabetes
  • Bone Tissue Engineering Materials

University of Verona
2016-2025

Azienda Ospedaliera Universitaria Integrata Verona
2018-2024

University of Udine
2024

Associazione Calabrese di Epatologia
2023

University of Padua
2003-2012

Istituto Oncologico Veneto
2009-2011

Maria Cecilia Hospital
2011

Istituti di Ricovero e Cura a Carattere Scientifico
2009-2011

Azienda Ospedaliera di Padova
2007-2010

Massachusetts General Hospital
2007-2008

Expansion of donor acceptance criteria for liver transplant increased the risk early allograft failure (EAF), and although EAF prediction is pivotal to optimize outcomes, there no consensus on specific indicators or timing evaluate EAF. Recently, Liver Graft Assessment Following Transplantation (L-GrAFT) algorithm, based aspartate transaminase, bilirubin, platelet, international normalized ratio kinetics, was developed from a single-center database gathered 2002 2015.To develop validate...

10.1001/jamasurg.2020.4095 article EN cc-by JAMA Surgery 2020-10-28

This prospective study analyzed the dropout probability and intention-to-treat survival rates of patients with hepatocellular carcinoma (HCC) selected treated according to our policy before liver transplantation (LT), particular attention those exceeding Milan criteria. Exclusion criteria for LT were macroscopic vascular invasion, metastases, poorly differentiated disease at percutaneous biopsy. A specific multi-modal adjuvant algorithm was used treat HCC LT. total 100 listed LT: 40 exceeded...

10.1111/j.1600-6143.2006.01719.x article EN cc-by-nc-nd American Journal of Transplantation 2007-03-26

The epithelial to mesenchymal transition (EMT) is a multi-factorial biological mechanism involved in renal and hepatic fibrosis the IL-1 beta has been assumed as mediator of this process although data are not exhaustive. Therefore, aim our study was evaluate role cytokine EMT proximal tubular cells (HK-2) stellate (LX-2) protective/anti-fibrotic effect its inhibition by Canakinumab (a specific human monoclonal antibody targeted against IL-1beta).Both cell types were treated with (10 ng/ml)...

10.1186/s12967-019-1770-1 article EN cc-by Journal of Translational Medicine 2019-01-07

Hepatocytes and stem cells transplantation may be an alternative to liver in acute or chronic disease. We aimed evaluate the therapeutic potential of mesenchymal from human umbilical cord (UCMSCs), a readily available source cells, CCl4-induced injury model. Mesenchymal profile was analyzed by flow cytometry. In order capability our UCMSCs differentiate hepatocytes, were seeded on three different supports, untreated plastic support, MatrigelTM acellular matrix. Cells immunocitochemistry for...

10.1186/1471-230x-12-88 article EN cc-by BMC Gastroenterology 2012-07-12

Antioxidant agents have the potential to reduce ischemia/reperfusion damage organs for liver transplantation (LT). In this prospective, randomized study, we tested impact of an infusion N-acetylcysteine (NAC) during procurement on post-LT outcomes. Between December 2006 and July 2009, 140 grafts were transplanted into adult candidates with chronic disease who listed first LT, according a sequential, closed-envelope, single-blinded procedure, these patients randomly assigned in 1/1 ratio NAC...

10.1002/lt.23527 article EN Liver Transplantation 2012-08-03

// Elisabetta Trevellin 1,* , Marco Scarpa 2,* Amedeo Carraro 3 Francesca Lunardi 4 Andromachi Kotsafti 2 Andrea Porzionato 5 Luca Saadeh Matteo Cagol Rita Alfieri Umberto Tedeschi Fiorella Calabrese Carlo Castoro and Roberto Vettor 1 Department of Medicine, Internal Medicine 3, Endocrine-Metabolic Laboratory, University Padova, Italy Surgical Oncology Unit, Veneto Oncological Institute (IOV-IRCCS), General Surgery Odontoiatrics, Hospital Verona, Cardiothoracic Vascular Sciences, Molecular...

10.18632/oncotarget.3587 article EN Oncotarget 2015-03-14

Previous studies assessing the antibody response (AbR) to mRNA COVID-19 vaccines in solid organ transplant (SOT) recipients are limited by short follow-up, hampering analysis of AbR kinetics. We present ORCHESTRA SOT cohort assessed for at first dose (t0), second (t1), and within 3 ± 1 month (t2) after dose. analyzed 1062 patients (kidney, 63.7%; liver, 17.4%; heart, 16.7%; lung, 2.5%) 5045 health care workers (HCWs). The rates SOTs HCWs were 52.3% 99.4%. levels significantly higher than (p...

10.3390/microorganisms10051021 article EN cc-by Microorganisms 2022-05-12

BackgroundInternational consensus has recently introduced a new definition of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). We sought to analyse epidemiological trends, prognostic features, and transplant survival benefits MASLD non-MASLD patients waiting for liver transplantation (LT) in Italy.Materials methodsUtilising the Italian Transplant Registry database, we analysed data from adult listed primary LT due end-stage chronic disease between January 2012 December 2022....

10.1016/j.jhepr.2024.101147 article EN cc-by-nc-nd JHEP Reports 2024-06-22

Patients with HDV/HBV-related end-stage liver disease candidates for transplantation(LT) have traditionally been regarded as a special population, although their outcomes are controversial. A intention-to-treat(ITT) analysis of long-term HDV/HBV-coinfected patients waitlisted LT in Italy, between 2011-2020, was performed and compared to HBV-monoinfected candidates. Out 1,731 HBV-infected candidates, 1,237(71.5%) had HBV-monoinfection 494(28.5%) HDV/HBV-coinfection. At listing, were...

10.1016/j.ajt.2025.03.003 article EN cc-by American Journal of Transplantation 2025-03-01

Abstract More liver transplants (LT) are performed worldwide thanks to extended criteria donors (ECD). This is paralleled by a supposed increased risk of allograft failure (AF) at 90 and 365 days. study has been designed portray the LT practice investigate models AF prediction impact mitigation strategies for further improving graft patient outcomes. multicenter, international, non-competitive, observational two segment on consecutive LTs over periods (2017–2019 2022–2024). A steering...

10.1007/s13304-025-02078-4 article EN cc-by Updates in Surgery 2025-03-27

Background and aims: Besides the increased risk of perioperative morbidity, graft failure, mortality, majority PVT are diagnosed at liver transplantation (LT). Improving preoperative management patient selection may lead to better short-term long-term outcomes reduce a futile LT. The authors aimed identify predictors adverse after LT in patients with nonmalignant portal vein thrombosis (PVT) improve donor recipient matching by analyzing results Italian cohort recipients. Methods: Adult who...

10.1097/js9.0000000000001149 article EN cc-by-nc-nd International Journal of Surgery 2024-03-04

To date, caval sparing (CS) and total replacement (TCR) for recipient hepatectomy in liver transplantation (LT) have been compared only terms of surgical morbidity. Nonetheless, the CS technique is inherently associated with an increased manipulation native later exclusion venous outflow, which may increase risk intraoperative shedding tumor cells when LT performed HCC. A multicenter, retrospective study was to assess impact (CS vs. TCR) on posttransplant HCC recurrence among 16 European...

10.1097/lvt.0000000000000373 article EN Liver Transplantation 2024-03-29
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