Amedeo Carraro
- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Renal Transplantation Outcomes and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver physiology and pathology
- Transplantation: Methods and Outcomes
- Polyomavirus and related diseases
- Tissue Engineering and Regenerative Medicine
- Esophageal Cancer Research and Treatment
- 3D Printing in Biomedical Research
- Organ Donation and Transplantation
- Viral-associated cancers and disorders
- Hepatitis C virus research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- PI3K/AKT/mTOR signaling in cancer
- Hepatitis B Virus Studies
- Mesenchymal stem cell research
- Gallbladder and Bile Duct Disorders
- Cytomegalovirus and herpesvirus research
- Appendicitis Diagnosis and Management
- Chronic Kidney Disease and Diabetes
- Bone Tissue Engineering Materials
University of Verona
2016-2025
Azienda Ospedaliera Universitaria Integrata Verona
2018-2024
University of Udine
2024
Associazione Calabrese di Epatologia
2023
University of Padua
2003-2012
Istituto Oncologico Veneto
2009-2011
Maria Cecilia Hospital
2011
Istituti di Ricovero e Cura a Carattere Scientifico
2009-2011
Azienda Ospedaliera di Padova
2007-2010
Massachusetts General Hospital
2007-2008
Expansion of donor acceptance criteria for liver transplant increased the risk early allograft failure (EAF), and although EAF prediction is pivotal to optimize outcomes, there no consensus on specific indicators or timing evaluate EAF. Recently, Liver Graft Assessment Following Transplantation (L-GrAFT) algorithm, based aspartate transaminase, bilirubin, platelet, international normalized ratio kinetics, was developed from a single-center database gathered 2002 2015.To develop validate...
This prospective study analyzed the dropout probability and intention-to-treat survival rates of patients with hepatocellular carcinoma (HCC) selected treated according to our policy before liver transplantation (LT), particular attention those exceeding Milan criteria. Exclusion criteria for LT were macroscopic vascular invasion, metastases, poorly differentiated disease at percutaneous biopsy. A specific multi-modal adjuvant algorithm was used treat HCC LT. total 100 listed LT: 40 exceeded...
The epithelial to mesenchymal transition (EMT) is a multi-factorial biological mechanism involved in renal and hepatic fibrosis the IL-1 beta has been assumed as mediator of this process although data are not exhaustive. Therefore, aim our study was evaluate role cytokine EMT proximal tubular cells (HK-2) stellate (LX-2) protective/anti-fibrotic effect its inhibition by Canakinumab (a specific human monoclonal antibody targeted against IL-1beta).Both cell types were treated with (10 ng/ml)...
Hepatocytes and stem cells transplantation may be an alternative to liver in acute or chronic disease. We aimed evaluate the therapeutic potential of mesenchymal from human umbilical cord (UCMSCs), a readily available source cells, CCl4-induced injury model. Mesenchymal profile was analyzed by flow cytometry. In order capability our UCMSCs differentiate hepatocytes, were seeded on three different supports, untreated plastic support, MatrigelTM acellular matrix. Cells immunocitochemistry for...
Antioxidant agents have the potential to reduce ischemia/reperfusion damage organs for liver transplantation (LT). In this prospective, randomized study, we tested impact of an infusion N-acetylcysteine (NAC) during procurement on post-LT outcomes. Between December 2006 and July 2009, 140 grafts were transplanted into adult candidates with chronic disease who listed first LT, according a sequential, closed-envelope, single-blinded procedure, these patients randomly assigned in 1/1 ratio NAC...
// Elisabetta Trevellin 1,* , Marco Scarpa 2,* Amedeo Carraro 3 Francesca Lunardi 4 Andromachi Kotsafti 2 Andrea Porzionato 5 Luca Saadeh Matteo Cagol Rita Alfieri Umberto Tedeschi Fiorella Calabrese Carlo Castoro and Roberto Vettor 1 Department of Medicine, Internal Medicine 3, Endocrine-Metabolic Laboratory, University Padova, Italy Surgical Oncology Unit, Veneto Oncological Institute (IOV-IRCCS), General Surgery Odontoiatrics, Hospital Verona, Cardiothoracic Vascular Sciences, Molecular...
Previous studies assessing the antibody response (AbR) to mRNA COVID-19 vaccines in solid organ transplant (SOT) recipients are limited by short follow-up, hampering analysis of AbR kinetics. We present ORCHESTRA SOT cohort assessed for at first dose (t0), second (t1), and within 3 ± 1 month (t2) after dose. analyzed 1062 patients (kidney, 63.7%; liver, 17.4%; heart, 16.7%; lung, 2.5%) 5045 health care workers (HCWs). The rates SOTs HCWs were 52.3% 99.4%. levels significantly higher than (p...
BackgroundInternational consensus has recently introduced a new definition of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). We sought to analyse epidemiological trends, prognostic features, and transplant survival benefits MASLD non-MASLD patients waiting for liver transplantation (LT) in Italy.Materials methodsUtilising the Italian Transplant Registry database, we analysed data from adult listed primary LT due end-stage chronic disease between January 2012 December 2022....
Patients with HDV/HBV-related end-stage liver disease candidates for transplantation(LT) have traditionally been regarded as a special population, although their outcomes are controversial. A intention-to-treat(ITT) analysis of long-term HDV/HBV-coinfected patients waitlisted LT in Italy, between 2011-2020, was performed and compared to HBV-monoinfected candidates. Out 1,731 HBV-infected candidates, 1,237(71.5%) had HBV-monoinfection 494(28.5%) HDV/HBV-coinfection. At listing, were...
Abstract More liver transplants (LT) are performed worldwide thanks to extended criteria donors (ECD). This is paralleled by a supposed increased risk of allograft failure (AF) at 90 and 365 days. study has been designed portray the LT practice investigate models AF prediction impact mitigation strategies for further improving graft patient outcomes. multicenter, international, non-competitive, observational two segment on consecutive LTs over periods (2017–2019 2022–2024). A steering...
Background and aims: Besides the increased risk of perioperative morbidity, graft failure, mortality, majority PVT are diagnosed at liver transplantation (LT). Improving preoperative management patient selection may lead to better short-term long-term outcomes reduce a futile LT. The authors aimed identify predictors adverse after LT in patients with nonmalignant portal vein thrombosis (PVT) improve donor recipient matching by analyzing results Italian cohort recipients. Methods: Adult who...
To date, caval sparing (CS) and total replacement (TCR) for recipient hepatectomy in liver transplantation (LT) have been compared only terms of surgical morbidity. Nonetheless, the CS technique is inherently associated with an increased manipulation native later exclusion venous outflow, which may increase risk intraoperative shedding tumor cells when LT performed HCC. A multicenter, retrospective study was to assess impact (CS vs. TCR) on posttransplant HCC recurrence among 16 European...