- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease and Transplantation
- Viral-associated cancers and disorders
- Transplantation: Methods and Outcomes
- ATP Synthase and ATPases Research
- Alcohol Consumption and Health Effects
- Lung Cancer Research Studies
- Medical Imaging Techniques and Applications
- Advanced X-ray and CT Imaging
- Esophageal Cancer Research and Treatment
- Gallbladder and Bile Duct Disorders
- Frailty in Older Adults
- Diet, Metabolism, and Disease
- Mitochondrial Function and Pathology
- Radiomics and Machine Learning in Medical Imaging
- RNA modifications and cancer
- Nutrition and Health in Aging
University of Padua
2022-2024
Abstract Background The 2022 Barcelona Clinic Liver Cancer (BCLC) algorithm does not recommend liver resection (LR) in BCLC A patients with oligo-nodular (two or three nodules ≤3 cm) hepatocellular carcinoma (HCC). This sharply contrasts the therapeutic hierarchy concept, implying a precise treatment order exists within each stage. study aimed to compare outcomes of LR versus radiofrequency ablation (RFA) trans-arterial chemoembolization (TACE) patients. Methods meta-analysis adhering PRISMA...
BackgroundInternational consensus has recently introduced a new definition of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). We sought to analyse epidemiological trends, prognostic features, and transplant survival benefits MASLD non-MASLD patients waiting for liver transplantation (LT) in Italy.Materials methodsUtilising the Italian Transplant Registry database, we analysed data from adult listed primary LT due end-stage chronic disease between January 2012 December 2022....
In resected perihilar cholangiocarcinoma (PHC), positive ductal margin (DM) is associated with poor survival. There currently little knowledge about the impact of radial (RM) when DM negative. The aim this study was to evaluate incidence and role RM. Patients who underwent surgery between 2005 2017 where retrospectively reviewed stratified according positivity: an isolated RM-positive group ± RM group. Of 75 patients identified; 34 (45.3%) had R1 resection 17 alone. Survival poorer in...
In the context of spreading interest in textbook outcome (TO) evaluation different fields, we aimed to investigate an uncharted procedure, that is, laparoscopic microwave ablation (MWA) for hepatocellular carcinoma (HCC). Absence post-MWA complications, a hospital stay three days, no mortality nor readmission within 30 and complete response target lesion at CT scan defined TO achievement. Patients treated between January 2014 March 2021 were retrospectively reviewed, 521 patients eligible...
Abstract Sarcopenia, serving as a surrogate for frailty, is clinically significant in liver resection (LR) elderly hepatocellular carcinoma (HCC) patients. Our study aims to assess sarcopenia’s impact, measured by Psoas Muscle Index (PMI), on postoperative outcomes. We retrospectively studied patients aged ≥ 60 years who underwent LR HCC between 2014 and 2018. PMI, derived from preoperative CT scans, Textbook Outcome (TO) were assessed. A nomogram predicting overall survival (OS) was...
Background. A recent international consensus, achieved through the Delphi method, has introduced a new definition of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). Our objective was to analyse past and future epidemiological trends, prognostic features, transplant survival benefits MASLD non-MASLD patients waiting for liver transplantation (LT) in Italy. Materials methods. Utilizing Italian Transplant Registry database, we analysed data from adult listed primary due...