- Diagnosis and Treatment of Venous Diseases
- Venous Thromboembolism Diagnosis and Management
- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Peripheral Artery Disease Management
- Organ Donation and Transplantation
- Liver Disease and Transplantation
- Medical Imaging Techniques and Applications
- Thermoregulation and physiological responses
- Transplantation: Methods and Outcomes
- Diabetic Foot Ulcer Assessment and Management
- Radiation Detection and Scintillator Technologies
- Dental Implant Techniques and Outcomes
- Central Venous Catheters and Hemodialysis
- Entomological Studies and Ecology
- Liver Disease Diagnosis and Treatment
- Cardiac Valve Diseases and Treatments
- Bee Products Chemical Analysis
- Pneumocystis jirovecii pneumonia detection and treatment
- Atomic and Subatomic Physics Research
- Hepatitis C virus research
- Periodontal Regeneration and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Dermatologic Treatments and Research
- Vascular Procedures and Complications
National Institute for Public Policy Analysis
2024
National Institute for Public Policy
2024
Istituto Superiore di Sanità
2008-2023
Sapienza University of Rome
2003-2023
Istituto Nazionale di Statistica
2015-2021
Institute of Studies for the Integration of Systems
2020
Research for Action
2019
Irvine Valley College
2016
University of Chieti-Pescara
1992-2014
Université Paris Cité
2009
A proprietary lecithin delivery system of curcumin (Meriva) was evaluated in a controlled study to assess its efficacy alleviating the side effects cancer chemo‐ and radiotherapy 160 patients undergoing these treatments. In both cases, semi‐quantitative evaluation carried out using visual analogue scale, assessing also plasma free radical status all patients. Results showed that lecithinized might alleviate burden associated radiotherapy, suggesting anecdotal use various preparations as...
Organ transplantation, e.g., of the heart, liver, or kidney, is nowadays a routine strategy to counteract several lethal human pathologies. From literature data and from obtained in Italy, striking scenario appears well evident: women are more often donors than recipients. On other hand, recipients organs mainly males, probably reflecting gender bias incidence transplant-related The impact sex mismatch on transplant outcome remains debated, even though donor-recipient mismatch, due...
T his prospective clinical trial evaluated 134 implants in 81 patients. The were placed at the time of tooth extraction and not augmented with barrier membranes or graft materials. into good jaw bone anatomy quality restored by dentists familiar implant system. Fortyseven followed between 4 to 5 years a cumulative success rate 93.3%. Marginal levels measured for 61 patients 108 implants. average mesial‐distal measurements maxillary abutment connection 1.02 mm (SD ± 0.59) 1.36 0.78) an 32...
Background Bacterial infections remain a challenge to solid organ transplantation. Due the alarming spread of carbapenem-resistant gram negative bacteria, these organisms have been frequently recognized as cause severe in transplant recipients. Methods and Findings Between 15 May 30 September 2012 we enrolled 887 recipients Italy with aim describe epidemiology bacteria spreading, explore potential risk factors assess effect early isolation on recipients' mortality during first 90 days after...
Brånemark fixtures were originally placed in two stages, whereas titanium plasma-sprayed (TPS) solid-screws are one stage. Long-term survival rates for both types of implants excellent. Excellent have also been reported machined screw-shaped (MS) A small number studies compared different implant systems and methods placement.The purpose this study is to report clinical outcomes from a prospective longitudinal, multicenter comparing MS (Nobel Biocare, Yorba Linda, California, USA) either or...
The study compared, by a prospective, randomized method, 6 treatment options: A: Sclerotherapy; B: High-dose sclerotherapy; C: Multiple ligations; D: Stab avulsion; E: Foam-sclerotherapy; F: Surgery (ligation) followed sclerotherapy. Results were analyzed 10 years after inclusion and initial treatment. Endpoints of the variations in ambulatory venous pressure (AVP), refilling time (RT), presence duplex-reflux, number recurrent or new incompetent sites. patients, limbs, treated segments...
We propose to develop a high resolution positron emission tomography (PET) detector designed for animal imaging. The consists of 2-D array small bismuth germanate (BGO) crystals coupled via optical fibers multi-channel photomultiplier tube (MC-PMT). Though this approach offers several advantages over the conventional BGO block design, it does require that sufficient number scintillation photons be transported from crystal, down fiber and into PMT. In study we use simulations experimental...
Abstract We derive a class of efficient and stable algorithms Brownian dynamics using formula, derived by Suzuki, to express time-ordered operators. These are simpler than those Helfand from Runge-Kutta and, like algorithms, can be combined with SHAKE describe the constrained systems.
The study was planned to evaluate efficacy and costs of endovascular sclerotherapy (ES) in comparison with surgery associated a prospective (10-year follow-up), good-clinical-practice study. Patients varicose veins pure, superficial venous incompetence were included. Of the patients randomized into three groups 39 (group A) treated ES, 40 (B) + sclerotherapy, 42 only (C). Surgery consisted ligation SFJ (saphenofemoral junction) incompetent detected color duplex. preselected 150 patients, 121...
The ECAT III is a whole body positron tomograph which has been designed in collaborative effort between investigators at UCLA and EGandG/Ortec (Oak Ridge, Tennessee). primary emphasis the design on problems of imaging heart. In our experience with II UCLA, heart were: 1) gated studies would have serious image artifacts if scanning period was too short, 2) resolution system made quantitative measurements difficult, particularly those cases there significant activity blood pool. this...
In a previous, double-blind, placebo-controlled study we evaluated the efficacy of 3-month treatment with Pycnogenol for 156 patients osteoarthritis knee. significantly decreased joint pain and improved function as using WOMAC score walking performance on treadmill. this study, further investigated anti-inflammatory antioxidant activity in subset presenting elevated C-reactive protein (CRP) plasma-free radicals. Elevated CRP levels have been suggested to be associated disease progression...
Purpose: The growing numbers of diabetes cases in the developed world are followed by increasing people diagnosed with diabetic complications. Diabetic microangiopathies eye lead to development retinopathy involving gradual loss vision. Previous studies Pycnogenol® showed effectiveness for stopping progression preproliferative stages retinopathy. aim our study was show protective effects Pycnogenol early retinopathy, characterized mild moderate retinal edema absence hemorrhages or hard...
BackgroundInternational consensus has recently introduced a new definition of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). We sought to analyse epidemiological trends, prognostic features, and transplant survival benefits MASLD non-MASLD patients waiting for liver transplantation (LT) in Italy.Materials methodsUtilising the Italian Transplant Registry database, we analysed data from adult listed primary LT due end-stage chronic disease between January 2012 December 2022....
The aim of this study was to evaluate the development edema, and superficial deep vein thrombosis (DVT) prophylaxis with an oral profibrinolytic agent (Flite Tabs, 150 mg pinokinase, Aidan, Tempe, AZ, USA) in long-haul flights (7-8 hours), high-risk subjects. A group 300 subjects included; 76 were excluded for several problems including concomitant treat ments ; 204 randomized into 2 groups (active treatment or placebo) effects Flite Tabs. An exercise program used both groups. femoral,...
Raloxifene (RAL), a selective estrogen receptor modulator, is indicated for the prevention and treatment of postmenopausal osteoporosis. RAL, by decreasing bone turnover, prevents loss microarchitecture damage, reducing incidence osteoporotic fractures. Our previous in vitro data demonstrated that RAL modulates osteoclast activity by, at least part, an IL-6- TNF-α-dependent mechanism. In this study we evaluated effects (60 mg/d) on circulating levels these cytokines 14 women with Lumbar...
The aim of this study was to investigate the clinical efficacy oral Pycnogenol® (Horphag Research Ltd., UK) in patients with severe chronic venous insufficiency (CVI) comparison combination diosmin and hesperidin (Daflon®, Servier, France). A group 86 (CVI), hypertension, ankle swelling) previous history ulcerations received either Pycnogenol (capsules) 150 mg or 300 daily for 8 weeks Daflon, 1000 mg/day. All completed without dropouts. At end study, microcirculatory results indicated: a...
The aim of this independent study was to investigate differences in efficacy between oxerutins (Venoruton) and 500 mg micronized diosmin + hesperidin (D+H) (Daflon) patients with chronic venous insufficiency (CVI), evaluating venous-related quality life (Ve-QOL). A first group 90 severe hypertension (CVI, ankle swelling) randomized treatment or D+H. received oral (2 g/day); the D+H 3 (500 mg) tablets daily every 8 hours for weeks. second 122 comparable included a registry following same...
Superficial vein thrombosis is characterized by clotting of superficial veins (ie, following direct trauma) with minimal inflammatory components. thrombophlebitis a minimally thrombotic process associated changes and/or infection. Treatments generally include analgesics, elastic compression, anti-inflammatory agents, exercise and ambulation, and, in some cases, local or systemic anticoagulants. It better to avoid bed rest reduced mobility. Topical analgesia nonsteroidal, creams applied...
The aim of this study was to investigate the clinical efficacy oral Pycnogenol ® (Horphag Research Ltd, United Kingdom) in patients with diabetic microangiopathy. Patients without a history ulcerations were treated Pycnogenol. received (50 mg capsules, 3 times daily for total 150 4 weeks). A group 30 included (severe microangiopathy); comparable observed as controls (no treatment during observation period). All (age, 59 years; range, 55-68 male:female = 18:12) completed 4-week study. Also,...