- Transplantation: Methods and Outcomes
- Mechanical Circulatory Support Devices
- Renal Transplantation Outcomes and Treatments
- Cardiac Structural Anomalies and Repair
- Organ Transplantation Techniques and Outcomes
- Polyomavirus and related diseases
- Organ and Tissue Transplantation Research
- Viral Infections and Immunology Research
- RNA Interference and Gene Delivery
- Viral-associated cancers and disorders
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Heparin-Induced Thrombocytopenia and Thrombosis
- Quality and Safety in Healthcare
- Parathyroid Disorders and Treatments
- Organ Donation and Transplantation
- Eosinophilic Disorders and Syndromes
- Neuroendocrine Tumor Research Advances
- Occupational Health and Safety Research
- Cardiomyopathy and Myosin Studies
- MicroRNA in disease regulation
- Cardiovascular Issues in Pregnancy
- Cardiac Valve Diseases and Treatments
- Cardiac Ischemia and Reperfusion
- Liver Disease and Transplantation
- Safe Handling of Antineoplastic Drugs
Universidade Federal do Amazonas
2023
University of Insubria
2018
University of Padua
2008-2018
Regione del Veneto
2015-2016
University Medical Center Utrecht
2013
Azienda Ospedaliera di Desio e Vimercate
2008-2009
San Diego Cardiac Center
2008
University of Milan
1996
Cardiac allograft vasculopathy (CAV) is the leading cause of morbidity and mortality in heart transplantation (HT). We sought to investigate role coronary flow reserve (CFR) by contrast-enhanced transthoracic echocardiography (CE-TTE) CAV diagnosis. was defined as maximal intimal thickness (MIT) assessed intravascular ultrasound (IVUS) > or =0.5 mm. CFR left anterior descending artery 22 HT recipients at 6 +/- 4 years post-HT. diagnosed 10 patients (group A), 12 had normal coronaries B). The...
This multicenter case-controlled pilot study evaluated myocardial inflammatory burden (IB) and phenotype in endomyocardial biopsies (EMBs) with without pathologic antibody-mediated rejection (pAMR). Sixty-five EMBs from five European heart transplant centers were centrally reviewed as positive (grade 2, n = 28), suspicious 1, 7) or negative (n 30) for pAMR. Absolute counts of total, intravascular (IV) extravascular (EV) immunophenotyped mononuclear cells correlated pAMR grade, capillary C4d...
Photopheresis (ECP) is a new immunomodulatory therapy in which recipient lymphocytes are treated extracorporeally with 8-methoxypsoralen and ultraviolet light. The treatment seems to induce an inhibition of both humoral cellular rejection after transplantation.Since recurrent (RR) continues be severe complication heart transplantation (HTx) the immunosuppressive regimes used for often associated increased morbidity mortality, we investigated whether ECP could have beneficial effect on number...
Plaque hemorrhage, inflammation and microvessel density are key determinants of plaque vulnerability in native coronary atherosclerosis (ATS). This study investigates the role intraplaque hemorrhage (IPH) its relation with microvessels cardiac allograft vasculopathy (CAV) posttransplanted patients. Seventy plaques were obtained from 12 patients who died because CAV. For each patient we collected both heart allograft, at time transplantation autopsy, respectively. Intralesion inflammation,...
Post-transplant lymphoproliferative disorders (PTLD) is a serious complication after solid organ transplantation. Reduction of immunosuppression (RI) alone not able to control the disease. We report prospective analysis 30 patients with PTLD heart or kidney Only 5 patients, treated solely RI, obtained complete response. Five were heterogeneously; in remaining 20, efficacy and safety weekly anthracycline-based chemotherapy assessed. Sixteen remission. One death was related treatment. With...
We report the case of a 68-year-old woman who underwent heart transplantation for hypertrophic cardiomyopathy. Two months after transplant she developed mild fever and dyspnea with marked drop in left ventricle ejection fraction 31%. Coronary angiography was negative cardiac allograft vasculopathy. Endomyocardial biopsy revealed ischemic damage no evidence acute cellular rejection, antibody-mediated rejection or viral myocarditis. A neoplastic process suspected even though full-body...
Alcohol-related liver disease is one of the most prevalent diseases worldwide and second common indication for transplantation. Most transplant programs require 6 months abstinence prior to transplantation; commonly referred as six-month rule. According this rule, patients admitted severe acute alcoholic hepatitis are not eligible transplantation in centers. However, there increasing evidence that if performed selected after first episode decompensation with no response steroid therapy, it...
Várias métricas de avaliação para geração texto foram propostas nos últimos anos. No entanto, muitas questões surgiram sobre o quão bem elas podem avaliar a acurácia e qualidade do gerado. Neste trabalho, estudamos como algumas das mais populares se comportam ao lidar com tarefa sumarização no domínio jurídico em Português. Mais especificamente, avaliamos cinco -- ROUGE, BERTScore, BARTScore, BLEURT MoverScore --, usando um dataset contendo 892 acórdãos Superior Tribunal Justiça. Cada item é...