- Mechanical Circulatory Support Devices
- Cardiovascular Function and Risk Factors
- Cardiac Structural Anomalies and Repair
- Heart Failure Treatment and Management
- Cardiac Valve Diseases and Treatments
- Cardiomyopathy and Myosin Studies
- Transplantation: Methods and Outcomes
- Congenital Heart Disease Studies
- Aortic Disease and Treatment Approaches
- Cardiac Imaging and Diagnostics
- Hemodynamic Monitoring and Therapy
- Infective Endocarditis Diagnosis and Management
- Cardiac pacing and defibrillation studies
- Ultrasound in Clinical Applications
- Cardiac and Coronary Surgery Techniques
- Viral Infections and Immunology Research
- Cardiac Arrhythmias and Treatments
- Cardiovascular Issues in Pregnancy
- Liver Disease Diagnosis and Treatment
- Potassium and Related Disorders
- Cardiovascular Effects of Exercise
- Aortic aneurysm repair treatments
- Acute Myocardial Infarction Research
- Renal and Vascular Pathologies
- Advanced MRI Techniques and Applications
Ospedale Vincenzo Cervello
2022-2023
Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione
2010-2022
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2022
Tunisia Polytechnic School
2016
City Clinical Hospital
2016
Oslo University Hospital
2016
Southern Medical University
2016
Nanfang Hospital
2016
Royal Brompton Hospital
2016
Medical University of Warsaw
2016
Sacubitril/valsartan has been shown to be superior enalapril in reducing the risks of death and hospitalization for heart failure (HF). However, knowledge impact on cardiac performance remains limited. We sought evaluate effects sacubitril/valsartan clinical, biochemical echocardiographic parameters patients with reduced ejection fraction (HFrEF).Sacubitril/valsartan was administered 205 HFrEF patients.Among 230 (mean age 59 ± 10 years, 46% ischemic disease) (89%) completed study. After a...
The aim of this study was to test the impact donor and recipient characteristics on development primary graft failure (PGF) after heart transplantation (HT) by focusing donor's inotropic support. Heart donors matched recipients data were prospectively collected. Univariate multivariate analyses used determine independent predictors for PGF peri-operative mortality. high inotrope requirement defined as sustained need dopamine exceeding 10 microg/kg/min and/or alpha agonists 0.06...
Identifying candidates for left ventricular assist device surgery at risk of right failure remains difficult. The aim was to identify the most accurate predictors among clinical, biological, and imaging markers, assessed by agreement different supervised machine learning algorithms.Seventy-four patients, referred HeartWare since 2010 in two Italian centers, were recruited. Biomarkers, standard, strain echocardiography, as well cath-lab measures, compared patients who did not develop (N =...
Cardiac amyloidosis (CA) is cardiomyopathy with a hypertrophic phenotype characterised by diffuse deposition of anomalous fibrillar proteins in the extracellular matrix.To evaluate prevalence and diagnostic value extra left ventricle echocardiographic findings patients ventricular (LV) amyloid deposition.A group 146 LV thickness ≥15 mm were enrolled: 70 who received definite diagnosis sarcomeric (HCM group) 76 transthyretin cardiac (CA group). Echocardiographic analysis crista terminalis...
Abstract Aims Echocardiographic assessment of left ventricular filling pressures is performed using a multi‐parametric algorithm. Unselected sample patients with heart failure reduced ejection fraction (HFrEF) may demonstrate an indeterminate status diastolic indices making interpretation challenging. We sought to test improvement in the diagnostic accuracy standard and strain echocardiography ventricle atrium (LA) estimate pulmonary capillary wedge pressure (PCWP) > 15 mmHg HFrEF....
Risk stratification is a crucial issue in heart failure. Clinicians seek useful tools to tailor therapies according patient risk. A prospective, observational, multicenter study on stable chronic failure outpatients with reduced left ventricular ejection fraction (HFrEF). Baseline demographics, blood, natriuretic peptides (NPs), high-sensitivity troponin I (hsTnI), and echocardiographic data, including the ratio between tricuspid annular plane excursion systolic pulmonary artery pressure...
Peripheral neuropathy can affect patients with heart failure, though its prevalence is unknown. After transplantation, it influence the postoperative course and quality of life, but screening for neuromuscular disease not routinely performed.The aim this study was to identify factors associated in a population failure who are candidates transplantation.Data regarding patients' clinical history, including recent hospitalizations, were collected. All underwent complete neurological examination...
Background: Sacubitril/valsartan has been shown to be superior enalapril in reducing the risks of death and hospitalization for heart failure (HF). However effect on cardiac performance remains unknown. We sought evaluate effects sacubitril/valsartan clinical, bioumoral echocardiographic parameters patients with HFrEF. Methods: was administered 205 HFrEF patients. Results: Among 230 (mean age 59 ± 10 years, 46% ischemic disease) (89%) completed study. After a follow–up...
Abstract Use of continuous flow left ventricle assist device (CF‐LVAD) in advanced heart failure (HF) patients results clinically relevant improvements survival, functional capacity, and quality life. Peripheral artery disease (PAD) can occur with CF‐LVAD due to the high rate concomitance between risk factors for atherosclerosis HF. Diagnosis PAD be difficult specific setting a patient supported by this kind because marked alteration waveform morphology velocity created artificial physiology...