- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiovascular and exercise physiology
- Heart Failure Treatment and Management
- Pulmonary Hypertension Research and Treatments
- Cardiac Valve Diseases and Treatments
- Hemodynamic Monitoring and Therapy
- Cardiac Health and Mental Health
- Heart Rate Variability and Autonomic Control
- Mechanical Circulatory Support Devices
- Acute Myeloid Leukemia Research
- Obstructive Sleep Apnea Research
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Effects of Exercise
- Cardiovascular Syncope and Autonomic Disorders
- Transplantation: Methods and Outcomes
- Advanced MRI Techniques and Applications
- Atrial Fibrillation Management and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- ECG Monitoring and Analysis
- Advanced X-ray and CT Imaging
- Cardiac pacing and defibrillation studies
- Nutrition and Health in Aging
- Cardiovascular Disease and Adiposity
- Hematopoietic Stem Cell Transplantation
Istituti Clinici Scientifici Maugeri
2000-2025
CY Cergy Paris Université
2025
École Supérieure des Sciences Économiques et Commerciales
2025
Laboratoire d'Informatique de Paris-Nord
2018-2022
Université Sorbonne Paris Nord
2018-2022
Centre National de la Recherche Scientifique
2022
Sorbonne Université
2022
Fondazione Salvatore Maugeri
2002-2020
Tescan (Czechia)
2015
Istituti di Ricovero e Cura a Carattere Scientifico
2000-2014
Background— The predictive value of heart rate variability (HRV) in chronic failure (CHF) has never been tested a comprehensive multivariate model using short-term laboratory recordings designed to avoid the confounding effects respiration and behavioral factors. Methods Results— A survival for identification sudden (presumably arrhythmic) death was developed with data from 202 consecutive patients referred between 1991 1995 moderate severe CHF (age 52±9 years, left ventricular ejection...
Mitral flow velocity patterns (MFVPs) evaluated by Doppler echocardiography are strong predictors of survival in various cardiac diseases. However, MFVPs may change over time according to loading conditions. We performed this prospective study assess whether changes MFVP induced manipulations provided additional prognostic information 173 patients with chronic heart failure.Simultaneous echocardiographic and right-sided hemodynamic recordings were obtained at baseline all patients, during...
Because of the demographic shift and increased proportion patients surviving acute critical illnesses, number people living with severely disabling chronic diseases and, consequently, demand for rehabilitation are expected to increase sharply overtime. As underscored by World Health Organization (WHO), there is substantial evidence that provision inpatient in specialized units complex needs effective fostering functional recovery, improving health-related quality life, increasing...
Due to epidemiological and social changes related the increase in average life expectancy, hospital users are characterized by elderly chronic comorbid patients who require recurrent hospitalizations often with disability outcomes. In this framework, an innovative clinical management hospitalization model is adequate answer systematically promote patient independence. Main features interdisciplinary integrated care pathways facing both disease biologically functionally diagnosed ICD ICF. The...
It is uncertain whether exposure to renin-angiotensin system (RAS) modifiers affects the severity of new coronavirus disease 2019 (COVID-19) because most available studies are retrospective.We tested prognostic value RAS (either angiotensin-converting enzyme inhibitors [ACE-Is] or angiotensin receptor blockers [ARBs]) in a prospective study hypertensive patients with COVID-19. We analyzed data from 566 (mean age 75 years, 54% males, 162 ACE-Is users, and 147 ARBs users) hospitalized five...
Aimsheart failure (HF) and coronary artery disease (CAD) are independent predictors of death in patients with COVID-19. The adverse prognostic impact the combination HF CAD these is unclear.Methods resultswe analysed data from 954 consecutive hospitalized for SARS-CoV-2 five Italian Hospitals February 23 to May 22, 2020. study was a systematic prospective collection according pre-specified protocol. All-cause mortality during hospitalization outcome measure.Mean duration 33 days. Mortality...
The proliferative activity of bone marrow cells was studied in 24 patients with primary dysmyelopoiesis by means flow cytometry and 3H-IdR autoradiography. Abnormal DNA content found two cases aneuploid karyotypes. typical a diploid population observed all normal karyotype three chromosomal aberrations. fraction S-and G2-phase higher acquired sideroblastic anemia refractory (without excess blasts) than blasts chronic myelomonocytic leukemia. Regardless to the diagnosis, low S- had short...
Objective Strenuous exercise variably modifies cardiovascular function. Only few data are available on intermediate levels of effort. We therefore planned a study in order to address the hypothesis that half marathon distance would result transient changes cardiac mechanics, neural regulation and biochemical profile suggestive complex, integrated adaptation. Methods enrolled 35 amateur athletes (42±7 years). Supine standing heart rate variability complete echocardiographic evaluation were...
Abstract DNA flow cytometric analysis of unfixed bone marrow cells stained with propidium iodide was carried out in 33 patients untreated primary myelodysplastic syndromes. Patients stable clinical course for up to 3 years had higher fractions S and G 2 phases (22.7 ± 12.4% 12 3.6%) than those who developed acute leukemia and/or died early the disease (14.4 8.5% 6.6 4%). Median survival more 36 mo S+G cell fraction 24%, 14 remaining 16 lower values (P < 0.01). Analyses repeated after 3–24...