Paolo Angeli
A5007434584- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Organ Transplantation Techniques and Outcomes
- Drug-Induced Hepatotoxicity and Protection
- Hepatitis C virus research
- Hepatocellular Carcinoma Treatment and Prognosis
- Electrolyte and hormonal disorders
- Renal function and acid-base balance
- Acute Kidney Injury Research
- Hepatitis B Virus Studies
- Hepatitis Viruses Studies and Epidemiology
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Eicosanoids and Hypertension Pharmacology
- Metabolism and Genetic Disorders
- Thermal Regulation in Medicine
- Hormonal Regulation and Hypertension
- Clinical Nutrition and Gastroenterology
- Alcohol Consumption and Health Effects
- Liver Diseases and Immunity
- COVID-19 Clinical Research Studies
- Epilepsy research and treatment
- Diet and metabolism studies
- Cardiovascular Function and Risk Factors
- Blood Pressure and Hypertension Studies
- Sepsis Diagnosis and Treatment
University of Padua
2016-2025
European Foundation for the Study of Chronic Liver Failure
2016-2025
Grifols (Spain)
2018-2024
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2024
University of Bologna
1991-2024
Institute of Liver and Biliary Sciences
2024
Charité - Universitätsmedizin Berlin
2020-2023
Sorbonne Université
2020-2023
Pitié-Salpêtrière Hospital
2020-2023
Goethe University Frankfurt
2020-2023
Bacterial infections are very common and represent one of the most important reasons progression liver failure, development liver-related complications, mortality in patients with cirrhosis. In fact, bacterial may be a triggering factor for occurrence gastrointestinal bleeding, hypervolemic hyponatremia, hepatic encephalopathy, kidney acute-on-chronic failure. Moreover, cause repeated hospitalizations, impaired health-related quality life, increased healthcare costs develop as consequence...
Acute renal failure (ARF) is a common complication in patients with decompensated cirrhosis. The traditional diagnostic criteria of these were proposed 19961 and have been refined subsequent years.2 According to criteria, ARF defined as an increase serum creatinine (sCr) ≥50% from baseline final value >1.5 mg/dL (133 µmol/L). However, the threshold 1.5 mg/dL (133 µmol/L) sCr define cirrhosis has challenged.3 ,4 In addition, timeframe distinguish acute chronic not clearly identified, only...
Acute‐on‐chronic liver failure (ACLF) is characterized by acute decompensation (AD) of cirrhosis, organ failure(s), and high 28‐day mortality. We investigated whether assessments patients at specific time points predicted their need for transplantation (LT) or the potential futility care. assessed clinical courses 388 who had ACLF enrollment, from February through September 2011, during early (28‐day) follow‐up prospective multicenter European Chronic Liver Failure (CLIF) in Cirrhosis study....
Acute renal failure (ARF) is a common complication in patients with decompensated cirrhosis. The traditional diagnostic criteria of these were proposed 19961 and have been refined subsequent years.2 According to criteria, ARF defined as an increase serum creatinine (sCr) ≥50% from baseline final value >1.5 mg/dL (133 µmol/L). However, the threshold 1.5 mg/dL (133 µmol/L) sCr define cirrhosis has challenged.3 ,4 In addition, timeframe distinguish acute chronic not clearly identified, only...
Low serum sodium concentration is an independent predictor of mortality in patients with cirrhosis, but its prevalence and clinical significance unclear. To evaluate prospectively the low association between levels severity ascites complications prospective data were collected on 997 consecutive from 28 centers Europe, North South America, Asia for a period days. The as defined by < or =135 mmol/L, =130 =125 =120 mmol/L was 49.4%, 21.6%, 5.7%, 1.2%, respectively. (<135 mmol/L) high both...
•Patients with acutely decompensated cirrhosis without ACLF develop 3 different clinical courses.•Patients pre-ACLF within 90 days and have high systemic inflammation mortality.•Patients unstable suffer from complications of severe portal hypertension.•Patients stable less frequent lower 1-year mortality risk. Background & AimsAcute decompensation (AD) is defined as the acute development ascites, gastrointestinal hemorrhage, hepatic encephalopathy, infection or any combination thereof,...
The aim of the study was to investigate prevalence and clinical course renal failure that induced by various types bacterial infections in patients with cirrhosis ascites. Three hundred nine patients, who were consecutively admitted 3 major hospitals Padova, Italy, during first 6 months 2005, studied prospectively. Of these, 233 (75.4%) had evidence In 104 ascites (44.6%) a infection diagnosed. A infection-induced observed 35 (33.6%). higher biliary or gastrointestinal tract spontaneous...
Hepatorenal syndrome (HRS), a serious complication of cirrhosis, is associated with high mortality without treatment. Terlipressin albumin effective in the reversal HRS. Where terlipressin not available, as United States, midodrine and octreotide are used an alternative treatment The aim was to compare effectiveness plus versus HRS randomized controlled trial. Twenty‐seven patients were receive (TERLI group) 22 (MID/OCT group). TERLI group received by intravenous infusion, initially 3 mg/24...
In patients with cirrhosis and hepatorenal syndrome (HRS), terlipressin has been used either as continuous intravenous infusion or boluses. To date, these two approaches have never compared. The goal of this study was to compare the administration versus boluses in treatment type 1 HRS. Seventy‐eight were randomly assigned receive (TERLI‐INF group) at initial dose 2 mg/day (TERLI‐BOL 0.5 mg every 4 hours. case no response, progressively increased a final 12 both groups. Albumin given same...