A5076347297- Linguistic Studies and Language Acquisition
- Language, Metaphor, and Cognition
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Educational and Social Studies
- Italian Literature and Culture
- Diverse academic and cultural studies
- Natural Language Processing Techniques
- Language, Discourse, Communication Strategies
- Electrolyte and hormonal disorders
- linguistics and terminology studies
- Venous Thromboembolism Diagnosis and Management
- Acute Kidney Injury Research
- Educational Tools and Methods
- Management, Economics, and Public Policy
- Organ Transplantation Techniques and Outcomes
- Drug-Induced Hepatotoxicity and Protection
- Teaching and Learning Programming
- Hepatitis C virus research
- Lexicography and Language Studies
- Cardiac Health and Mental Health
- Virus-based gene therapy research
- Distributed and Parallel Computing Systems
- Urban Planning and Valuation
- Renal function and acid-base balance
University of Cagliari
2009-2023
University of Padua
1999-2019
657 Oslo
2016
Consorzio CREO (Italy)
2015
Kyushu University
2013
Institute for Computational Linguistics “A. Zampolli”
2000
University of Milan
1965
In patients with cirrhosis and hepatorenal syndrome (HRS), terlipressin has been used either as continuous intravenous infusion or boluses. To date, these two approaches have never compared. The goal of this study was to compare the administration versus boluses in treatment type 1 HRS. Seventy‐eight were randomly assigned receive (TERLI‐INF group) at initial dose 2 mg/day (TERLI‐BOL 0.5 mg every 4 hours. case no response, progressively increased a final 12 both groups. Albumin given same...
Spontaneous bacterial peritonitis (SBP) is a common, life‐threatening complication of liver cirrhosis. Third‐generation cephalosporins have been considered the first‐line treatment SBP. In 2014, panel experts suggested broader spectrum antibiotic regimen for nosocomial SBP, according to high rate bacteria resistant third‐generation found in these patients. However, broader‐spectrum has never compared The aim our study was compare meropenem plus daptomycin versus ceftazidime Patients with...
The aim of this study was to evaluate the effect and molecular mechanism albumin infusion on cardiac contractility in experimental cirrhosis with ascites. Cardiac recorded ex vivo rats ascites control after injection caudal vein albumin, saline, or hydroxyethyl starch (HES). Gene protein expression β-receptors pathways involved their intracellular signaling such as Gα(i2) (Gα(i2)), adenylate cyclase 3 (Adcy3), tumor necrosis factor alpha (TNF-α) inducible nitric oxide synthase (iNOS), were...
The project LE-SIMPLE is an innovative attempt of building harmonized syntactic-semantic lexicons for twelve European languages, aimed at use in different Human Language Technology applications. SIMPLE provides a general design model the encoding large amount semantic information, spanning from ontological typing, to argument structure and terminology. thus framework resource development, where state-of-the-art results lexical semantics are coupled with needs Engineering applications...
Summary Background & Aims A moderate sodium restriction diet should be indicated in patients with cirrhosis and ascites. Nevertheless, there is a lack of specific investigation on its correct application. To evaluate the adherence ascites to moderately low‐salt impact intake total calories serum concentration. Methods 120 outpatients were interviewed pre‐established questionnaire. quantitative assessment nutrient salt was performed. Result followed by 37 (Group A). Of 83 who did not...
The detection of alcohol consumption in liver transplant candidates (LTCs) and recipients (LTRs) is required to enable a proper assessment eligibility early management relapse, respectively. In this clinical setting, urinary ethyl glucuronide (uEtG), the Alcohol Use Disorders Identification Test for Consumption (AUDIT-c), serum ethanol, carbohydrate-deficient transferrin (CDT), other indirect markers were evaluated compared prospectively 121 LTCs LTRs. was diagnosed when AUDIT-c results...
The new International Club of Ascites diagnostic criteria to diagnose acute kidney injury at hospital admission suggests the possibility using a presumed baseline serum creatinine, defined as last least two stable creatinine values during 3 months. Nevertheless, lack such value still remains. In these patients, KDIGO suggest use an inverse application MDRD equation assuming that glomerular filtration rate is 75 ml/min per 1.73 m(2) (imputed creatinine). We tested accuracy this approach...
Mental stress is one of the main risk factors for cardiovascular disease. Meditation and music listening are two techniques that able to counteract it through activation specific brain areas, eliciting so-called Relaxing Response (RR). Epidemiological evidence reveals RR practice has a beneficial prognostic impact on patients after myocardial infarction. We aimed study possible molecular mechanisms underlying these findings.We enrolled 30 consecutive infarction 10 healthy controls. were...
Mental stress is potentially a major cardiovascular risk factor. Meditation and listening to music may be able compensate by eliciting the Relaxation Response (RR) with beneficial prognostic impact after myocardial infarction (MI), reducing progression of arteriosclerotic process improving coronary blood flow. We aimed study possible epigenetic mechanism RR speculating that circulating microRNAs levels could change during relaxation. enrolled 150 consecutive patients MI. 50 were trained...
Although the induction of cytochrome P450 (CYP) has long been investigated in patients with cirrhosis, question whether liver dysfunction impairs response to CYP inducers still remains unresolved. Moreover, mechanism underlying possible effect cirrhosis on not investigated. Since ethical constraints do permit methodologically rigorous studies humans, this was addressed by investigating prototypical inducer benzo[a]pyrene (BP) CYP1A1 and CYP1A2 cirrhotic rats stratified according severity...
Social networks are really useful tools for public communication if we able to manage them improve the effectiveness of our messages in terms engagement citizens.Health is no exception.On contrary, it a fertile ground on which innovate make patients' lives easier, increasing online services and stimulating interaction communicating with patients.On this basis, present research about social applied services.We analyze it, individuating crucial matters innovative solutions.Social transparency,...
The present study examines the relationship between pictorial similes and hybrid metaphors. results suggest that metaphors are perceived more strongly than when they presented on their own in corrective convention but not verbalized. We argue have transformational effects as fusion of two concepts allow reader to see one thing terms another. Juxtaposition a simile merely suggests search for similarity, which is explicit. Results also showed verbalized metaphor (X Y) or like forms often used...
Antiangiogenic therapy may represent a promising approach to cancer treatment. Indeed, the efficacy of endogenous angiogenesis inhibitors, including angiostatin, endostatin and TIMPs, has been demonstrated in many types solid tumors animal models. In view possible problems associated with long-term administration inhibitors as recombinant proteins, we propose their delivery nucleic acids through gene approach. To this end, eukaryotic expression constructs for murine angiostatin well human...