A5082435351- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Organ Transplantation Techniques and Outcomes
- Drug-Induced Hepatotoxicity and Protection
- Hepatitis B Virus Studies
- Transplantation: Methods and Outcomes
- Electrolyte and hormonal disorders
- Acute Kidney Injury Research
- Renal Transplantation Outcomes and Treatments
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Hepatocellular Carcinoma Treatment and Prognosis
- Inflammasome and immune disorders
- Sepsis Diagnosis and Treatment
- Organ and Tissue Transplantation Research
- Enhanced Recovery After Surgery
- Genetic factors in colorectal cancer
- MicroRNA in disease regulation
- Body Contouring and Surgery
- Liver physiology and pathology
- Renal function and acid-base balance
- Heparin-Induced Thrombocytopenia and Thrombosis
- Clinical Nutrition and Gastroenterology
- Muscle and Compartmental Disorders
- HIV/AIDS drug development and treatment
University of Padua
2014-2025
University of Campania "Luigi Vanvitelli"
2024
Ospedale di Mirano
2020
Italian Medicines Agency
2018
657 Oslo
2016
University of Naples Federico II
2008-2010
Gruppo Italiano per il Trapianto di Midollo Osseo
2007
Bilkent University
1999
In patients with cirrhosis and hepatorenal syndrome (HRS), terlipressin has been used either as continuous intravenous infusion or boluses. To date, these two approaches have never compared. The goal of this study was to compare the administration versus boluses in treatment type 1 HRS. Seventy‐eight were randomly assigned receive (TERLI‐INF group) at initial dose 2 mg/day (TERLI‐BOL 0.5 mg every 4 hours. case no response, progressively increased a final 12 both groups. Albumin given same...
Spontaneous bacterial peritonitis (SBP) is a common, life‐threatening complication of liver cirrhosis. Third‐generation cephalosporins have been considered the first‐line treatment SBP. In 2014, panel experts suggested broader spectrum antibiotic regimen for nosocomial SBP, according to high rate bacteria resistant third‐generation found in these patients. However, broader‐spectrum has never compared The aim our study was compare meropenem plus daptomycin versus ceftazidime Patients with...
Epidemiological data associate coffee consumption with a lower prevalence of chronic liver disease and reduced risk elevated enzyme levels (γ glutamyl transpeptidase alanine aminotransferase), advanced its complications, hepatocellular carcinoma. Knowledge the mechanisms underlying these effects components responsible for properties is still lacking. In this study, 1.5 mL/day decaffeinated or polyphenols melanoidins (corresponding to approximately 2 cups filtered 6 espresso 70-kg person)...
Introduction Patients with cirrhosis have a high risk of sepsis, which confers poor prognosis. The systemic inflammatory response syndrome (SIRS) criteria several limitations in cirrhosis. Recently, new for sepsis (Sepsis-3) been suggested the general population (increase Sequential Organ Failure Assessment (SOFA) ≥2 points from baseline). Outside intensive care unit (ICU), quick SOFA (qSOFA (at least two among alteration mental status, systolic blood pressure ≤100 mm Hg or respiratory rate...
<h3>Abstract</h3> Bioinformatic pipelines optimised for the processing and assessment of metagenomic ancient DNA (aDNA) are needed studies that do not make use high yielding capture techniques. These bioinformatic traditionally broad aDNA purposes, contingent on selection biases associated with costs. Here we present a pipeline identification without expensive Our actively conserves reads, allowing application approach by identifying shortest reads possible analysis (22-28bp). The time...
Summary Background & Aims A moderate sodium restriction diet should be indicated in patients with cirrhosis and ascites. Nevertheless, there is a lack of specific investigation on its correct application. To evaluate the adherence ascites to moderately low‐salt impact intake total calories serum concentration. Methods 120 outpatients were interviewed pre‐established questionnaire. quantitative assessment nutrient salt was performed. Result followed by 37 (Group A). Of 83 who did not...
Concerns about an increased hepatocellular carcinoma (HCC) recurrence rate following direct-acting antiviral (DAA) therapy in patients with cirrhosis a prior complete oncological response have been raised. Data regarding the impact of HCV treatment DAAs on wait-list dropout rates active HCC and HCV-related awaiting liver transplantation (LT) are lacking. HCV-HCC listed for LT between January 2015 May 2016 at Padua Liver Transplant Center were considered eligible study. After enrollment,...
The new International Club of Ascites diagnostic criteria to diagnose acute kidney injury at hospital admission suggests the possibility using a presumed baseline serum creatinine, defined as last least two stable creatinine values during 3 months. Nevertheless, lack such value still remains. In these patients, KDIGO suggest use an inverse application MDRD equation assuming that glomerular filtration rate is 75 ml/min per 1.73 m(2) (imputed creatinine). We tested accuracy this approach...
Autoimmune hepatitis (AIH) and drug-induced liver injury (DILI) are major causes of inflammation with distinct pathophysiology but overlapping clinical features. Among acute cases, DILI is a key differential diagnosis for AIH, especially when drug history unclear or the non-dose-dependent. Mechanisms include direct toxicity, metabolic idiosyncrasies, immune-mediated responses that can mimic AIH. Moreover, certain drugs induce AIH-like syndromes, further complicating diagnosis. While...