Peter Jarčuška
- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Liver Disease and Transplantation
- Romani and Gypsy Studies
- Liver Diseases and Immunity
- Alcohol Consumption and Health Effects
- Hepatitis Viruses Studies and Epidemiology
- Parasitic Infections and Diagnostics
- Pediatric Hepatobiliary Diseases and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Hemoglobinopathies and Related Disorders
- Autopsy Techniques and Outcomes
- Diet, Metabolism, and Disease
- Parasitic infections in humans and animals
- Electrolyte and hormonal disorders
- Liver physiology and pathology
- Congenital Anomalies and Fetal Surgery
- Nutritional Studies and Diet
- Toxoplasma gondii Research Studies
- Cytomegalovirus and herpesvirus research
- Global Health Care Issues
- Helicobacter pylori-related gastroenterology studies
- Drug-Induced Hepatotoxicity and Protection
- Eosinophilic Esophagitis
University of Pavol Jozef Šafárik
2016-2025
Univerzitná Nemocnica Louisa Pasteura
2014-2025
University of Veterinary Medicine in Košice
2019-2022
Center for Disease Analysis
2022
European Foundation for the Study of Chronic Liver Failure
2021
Medical University of Białystok
2020
Technical University of Košice
2017
General University Hospital in Prague
2016
•Patients with acutely decompensated cirrhosis without ACLF develop 3 different clinical courses.•Patients pre-ACLF within 90 days and have high systemic inflammation mortality.•Patients unstable suffer from complications of severe portal hypertension.•Patients stable less frequent lower 1-year mortality risk. Background & AimsAcute decompensation (AD) is defined as the acute development ascites, gastrointestinal hemorrhage, hepatic encephalopathy, infection or any combination thereof,...
Acute decompensation (AD) of cirrhosis may present without acute-on-chronic liver failure (ACLF) (AD-No ACLF), or with ACLF (AD-ACLF), defined by organ failure(s). Herein, we aimed to analyze and characterize the precipitants leading both these AD phenotypes. The multicenter, prospective, observational PREDICT study (NCT03056612) included 1,273 non-electively hospitalized patients (No = 1,071; 202). Medical history, clinical data laboratory were collected at enrolment during 90-day...
Morbidity and mortality attributable to chronic hepatitis C virus (HCV) infection are increasing in many countries as the infected population ages. Models were developed for 15 quantify characterize viremic population, well estimate number of new infections HCV related deaths from 2013 2030. Expert consensus was used determine current treatment levels outcomes each country. In most countries, prevalence has already peaked. every country studied, begins decline before 2030, when held...
Summary Chronic hepatitis C virus ( HCV ) infection is a leading cause of liver related morbidity and mortality. In many countries, there lack comprehensive epidemiological data that are crucial in implementing disease control measures as new treatment options become available. Published literature, unpublished expert consensus were used to determine key parameters, including prevalence, viremia, genotype the number patients diagnosed treated. this study 15 viremic prevalence ranged from...
The objective of this study was to evaluate the possible benefits coenzyme Q 10 and selenium supplementation administered patients with statin-associated myopathy (SAM). Sixty eligible entered pilot study. Laboratory examination (CoQ10, selenium, creatin kinase) intensity SAM (visual scale) were performed at baseline, after 1 month, end month 3. Plasma levels CoQ10 increased from 0.81 ± 0.39 3.31 1.72 μmol/L in active group treated by CoQ10, compared placebo (p = 0.001). Also, symptoms...
Summary The hepatitis C virus ( HCV ) epidemic was forecasted through 2030 for 15 countries, and the relative impact of two scenarios considered: (i) increased treatment efficacy while holding treated population constant (ii) annual population. Increasing levels diagnosis treatment, in combination with improved efficacy, were critical achieving substantial reductions disease burden. In most had to increase several fold achieve largest ‐related morbidity mortality. This suggests that capacity...
Abstract The 69th World Health Assembly endorsed the Global Sector Strategy for Viral Hepatitis, embracing a goal to eliminate hepatitis infection as public health threat by 2030. This was followed Organization's (WHO) global targets care and management of B virus (HBV) C (HCV) infections. These announcements were important in raising awareness calling action; however, tracking countries’ progress towards these elimination goals has provided insights limitations targets. existing compare...
Background: A 69-year-old man with multiple myeloma and left-sided heart failure presented to the hospital a two-month fever. Method: transjugular liver biopsy was performed due rapid progression of failure. The procedure complicated by an intraperitoneal hemorrhage. bleeding managed expectantly. Result: Significantly elevated serum bilirubin levels occurred on 13th day after biopsy. Increasing were observed until patient’s death biliovenous fistula at site. Simultaneously, his slightly...
Background: Several studies have revealed a high prevalence of risk factors associated with unhealthy lifestyle among individuals lower socioeconomic status. In Slovakia, one the most socially and health-disadvantaged groups is Roma minority. The aim this study to explore differences in physical activity, smoking alcohol consumption between population living settlements majority Slovakia. Methods: Data from cross-sectional epidemiological HepaMeta conducted Slovakia 2011 were used. sample...
Background: The aim of this study was to compare socioeconomic characteristics the Roma population living in settlements with majority population. Moreover, it aimed assess differences health and health-related behaviour within settlements. Methods: Data from cross-sectional HepaMeta conducted Slovakia 2011 were used. sample consisted 452 (mean age = 34.7; 35.2% men) 403 non-Roma 33.5; 45.9% respondents. selected recruited by local community workers. Respondents major randomly a list...
Background and Aim. Accurate assessment of cirrhotic patient's prognosis is essential for decisions regarding the course treatment. Therefore we aimed to confirm quantify predictive value serum cholesterol triglycerides in liver cirrhosis patients. Material methods. We performed a retrospective observational cohort study on consecutive patients with (n = 191). Relevant clinical laboratory variables were obtained from patients' charts followed two months. Mortality was main outcome. Results....