Yee Tak Hui
- Inflammatory Bowel Disease
- Microscopic Colitis
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Diagnosis and treatment of tuberculosis
- Liver Disease Diagnosis and Treatment
- Colorectal Cancer Screening and Detection
- Eosinophilic Esophagitis
- Autoimmune and Inflammatory Disorders
- Gastric Cancer Management and Outcomes
- Esophageal Cancer Research and Treatment
- Gallbladder and Bile Duct Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Inflammatory mediators and NSAID effects
- Biliary and Gastrointestinal Fistulas
- Lymphoma Diagnosis and Treatment
- Hematological disorders and diagnostics
- Liver Diseases and Immunity
- Osteoarthritis Treatment and Mechanisms
- Mycobacterium research and diagnosis
- HIV/AIDS drug development and treatment
- Helicobacter pylori-related gastroenterology studies
- Renal Transplantation Outcomes and Treatments
- Pancreatic and Hepatic Oncology Research
- Pneumocystis jirovecii pneumonia detection and treatment
Queen Elizabeth Hospital
2008-2024
University of Hong Kong
2015
Chinese University of Hong Kong
2015
Incidence of inflammatory bowel disease (IBD) is increasing in Asia, but population-based prevalence data are limited. This study examined IBD incidence and based on results a territory-wide registry Hong Kong.We collected 2575 patients with (1541 ulcerative colitis [UC], 983 Crohn's [CD], 51 unclassified) from 1981 to 2014 using hospital administrative coding system. Prevalence incidence, phenotype, surgery, mortality were analyzed.Adjusted IBD, UC, CD, unclassified per 100,000 individuals...
Data on the natural history of elderly-onset ulcerative colitis [UC] are limited. We aimed to investigate clinical features and outcomes patients with UC. Patients a confirmed diagnosis UC between 1981 2013, from 13 hospitals within territory-wide Hong Kong Inflammatory Bowel Disease Registry, were included. Clinical patients, defined as age ≥ 60 years at diagnosis, compared those non-elderly-onset disease [< diagnosis]. identified 1225 whom 12.8% [157/1225; 56.1% male] had Median duration...
Abstract The 69th World Health Assembly endorsed the Global Sector Strategy for Viral Hepatitis, embracing a goal to eliminate hepatitis infection as public health threat by 2030. This was followed Organization's (WHO) global targets care and management of B virus (HBV) C (HCV) infections. These announcements were important in raising awareness calling action; however, tracking countries’ progress towards these elimination goals has provided insights limitations targets. existing compare...
Summary Due to the introduction of newer, more efficacious treatment options, there is a pressing need for policy makers and public health officials develop or adapt national hepatitis C virus ( HCV ) control strategies changing epidemiological landscape. To do so, detailed, country‐specific data are needed characterize burden chronic infection. In this study 17 countries, literature review published unpublished on prevalence, viraemia, genotype, age gender distribution, liver transplants...
Summary Factors influencing the morbidity and mortality associated with viremic hepatitis C virus (HCV) infection change over time place, making it difficult to compare reported estimates. Models were developed for 17 countries (Bahrain, Bulgaria, Cameroon, Colombia, Croatia, Dominican Republic, Ethiopia, Ghana, Hong Kong, Jordan, Kazakhstan, Malaysia, Morocco, Nigeria, Qatar Taiwan) quantify characterize population as well forecast changes in infected corresponding disease burden from 2015...
Whether low-dose azathioprine (AZA) is effective in maintaining remission patients with steroid-dependent ulcerative colitis (UC) remains unclear. We assessed the efficacy and safety of AZA a Chinese population UC.We identified UC clinical on maintenance therapy from territory-wide IBD Registry. Standard- were defined as at least 2 mg/kg/day less than mg/kg/day, respectively. Relapse rates analyzed by Kaplan-Meier analysis compared using log-rank test.Among 1226 patients, 128 (53% male,...
Abstract Background To study the epidemiology of chronic hepatitis C virus infection in Hong Kong and to estimate service gap for achieving WHO elimination targets attaining a diagnosis rate 90%, treatment 80% 65% reduction mortality by 2030. Methods From January 2005 March 2017, patients who were tested positive anti‐ HCV retrospectively retrieved from all public hospitals Kong. The epidemiological data 15 participating analysed. Results A total 11 309 + identified estimated was 50.9%. Our...
Abstract Background and Aim AmplifEYE is a mucosal exposure device mounted to the tip of colonoscope improve polyp or adenoma detection. We aim compare detection rates (ADR) AmplifEYE‐assisted colonoscopy (AC) with standard (SC). Methods performed randomized controlled trial involving patients aged 50 79 who underwent AC SC in two centers. Procedures were by five experienced colonoscopists. Results Three hundred fifty‐five recruited, 334 (170 164 SC) included into analysis. The ADR was...
With the rapid increase in incidence of inflammatory bowel disease (IBD) Asia, natural course early phase these patients remains poorly defined. This study aimed to determined and characteristics infection-related hospitalization first year newly diagnosed with IBD Hong Kong SAR, China.Patients enrolled territory-wide Registry were identified. Details their within 12 months after diagnosis retrieved analyzed.Altogether 433 enrolled, including 188 Crohn's (CD), 230 ulcerative colitis (UC) 15...
Background/Aims: Data on treatment efficacy and safety of glecaprevir/pibrentasvir (GLE/PIB) for chronic hepatitis C virus (HCV) infection in Asian patients with severe renal impairment are limited. This study aimed to the side effects GLE/PIB these infected non-1 genotype (GT) HCV.Methods: We prospectively recruited Child’s A cirrhosis eGFR <30 mL/min/1.73 m<sup>2</sup> Hong Kong Taiwan during 2017–2018 receive treatment.Results: Twenty-one (GT2, n=7; GT3, n=6; GT6, n=8)...
BackgroundMucosal healing (MH) has been associated with improved outcomes in ulcerative colitis but factors MH are not well defined.
Background Osteoarthritis (OA) is a common degenerative joint condition. Family physician plays an important role in the management. Objectives The guideline seeks to assist primary health care professionals help patients with OA knee improve quality of life using pharmacological measures relieve symptoms, drug use and reduce adverse incidents. Methods based on evidence-based literature review was synthesised accordance SIGN methodology. A systematic carried out explicit search strategy...