- Oral microbiology and periodontitis research
- Dental Implant Techniques and Outcomes
- Periodontal Regeneration and Treatments
- Oral and gingival health research
- Dental Health and Care Utilization
- HIV/AIDS oral health manifestations
- Streptococcal Infections and Treatments
- Oral Health Pathology and Treatment
- Dental materials and restorations
- Dental Radiography and Imaging
- Antiplatelet Therapy and Cardiovascular Diseases
- Atrial Fibrillation Management and Outcomes
- Reconstructive Surgery and Microvascular Techniques
- Cleft Lip and Palate Research
- Drug-Induced Adverse Reactions
- Cervical Cancer and HPV Research
- Diabetes and associated disorders
- Osteomyelitis and Bone Disorders Research
- Healthcare Systems and Public Health
- Venous Thromboembolism Diagnosis and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Reconstructive Facial Surgery Techniques
- Laser Applications in Dentistry and Medicine
- Spondyloarthritis Studies and Treatments
- Patient Satisfaction in Healthcare
Universidad Autónoma de Santo Domingo
2022
Sociedad Española de Cardiología
2016
Universidad de Málaga
2009-2014
Universidad de Granada
2014
Universitat de Barcelona
1996-2010
University College London
2003-2005
Eastman Dental Hospital
2003-2005
Abstract Background: The objective of this study was to assess the adjunctive clinical effect administration systemic amoxicillin and metronidazole in non‐surgical treatment generalized aggressive periodontitis (GAP). Methods: Forty‐one systemically healthy subjects with GAP were included 6‐month double‐blind, placebo‐controlled, randomized trial. Patients received a course full‐mouth periodontal delivered over 24 h period using machine‐driven hand instruments. Test an antibiotic consisting...
The aim of this secondary analysis is to explore whether the application different definition criteria periodontitis, used in other similar studies, has an influence on significance association between periodontitis and prematurity or low birth weight.Fourteen definitions more than 50 periodontal disease continuous measurements, found 23 published were applied a cohort study that included 1296 pregnant women. associations with adverse pregnancy outcomes analysed using logistic regression...
Abstract Aim To evaluate the non‐inferiority of adjunct a xenogeneic collagen matrix ( CMX ) or connective tissue graft CTG to coronally advanced flaps CAF for coverage multiple adjacent recessions and compare superiority in patient‐reported outcomes PROM ). Material methods One hundred eighty‐seven subjects (92 with 485 14 centres were randomized followed up 6 months. Patients filled daily diaries 15 days monitor experience. The primary outcome was changed position gingival margin....
To evaluate the prevalence of peri-implant diseases in Spain, as well associated risk indicators.This is a cross-sectional study using network sentinel dentists, who randomly selected 10 patients with implants (placed, at least, 5 years before), which were clinically and radiographically evaluated. Case definitions established for mucositis [bleeding on probing (BOP) no bone level ≥2 mm] peri-implantitis (BOP plus mm). Potential predictor variables, univariate multivariate levels, explored...
To evaluate the potential benefit of use a bone substitute material in reconstructive surgical therapy peri-implantitis.In this multicenter randomized clinical trial, 138 patients (147 implants) with peri-implantitis were treated surgically, by coin toss to either control (access flap surgery) or test group (reconstructive surgery using material). Clinical assessments, including probing pocket depth (PPD), bleeding and suppuration on (BOP & SOP) as well soft tissue recession (REC), recorded...
Griffiths GS, Ayob R, Guerrero A, Nibali L, Suvan J, Moles DR, Tonetti MS. Amoxicillin and metronidazole as an adjunctive treatment in generalized aggressive periodontitis at initial therapy or re-treatment: a randomized controlled clinical trial. J Clin Periodontol 2011; 38: 43–49. doi: 10.1111/j.1600-051X.2010.01632.x Abstract Background: Previously, we showed that systemic amoxicillin significantly improved the outcomes of non-surgical debridement patients. This study aimed to observe...
The aim of this study was to determine the association between periodontitis and incidence preterm birth (PB), low weight (LBW) (PLBW) MATERIAL AND METHODS: One thousand ninety-six women were enrolled. Periodontal data, pregnancy outcome variables information on other factors that may influence adverse outcomes collected. Data analysed using a logistic regression model.The PB LBW 6.6% 6.0%, respectively. PLBW 3.3%. related mother's age, systemic diseases, onset prenatal care, previous PBs,...
To explore whether subjects harbouring A. actinomycetemcomitans, P. gingivalis or T. forsythia at baseline showed increased clinical benefits with the adjunctive use of systemic amoxicillin and metronidazole (AMX-MET) during non-surgical treatment generalized aggressive periodontitis (GAgP).Forty one were included in this 6-month randomized placebo-controlled trial using a 7-day course AMX-MET placebo as adjuncts to periodontal therapy. Clinical microbiological parameters collected baseline,...
To identify predictors of treatment outcomes following surgical therapy peri-implantitis.We performed a secondary analysis data from randomized controlled trial (RCT) comparing access flap with or without bone replacement graft. Outcomes at 12 months were probing pocket depth (PPD), bleeding on (BOP), soft-tissue recession (REC) and marginal level (MBL) change. Multilevel regression analyses used to predictors. We also built an explanatory model for residual signs inflammation.Baseline PPD...
Abstract Aim: The objective of this study was to explore the effect incomplete adherence prescribed antibiotic regimen, amoxicillin and metronidazole, in non‐surgical treatment generalized aggressive periodontitis (GAP). Methods: This retrospective included 18 GAP subjects who received a conventional course full‐mouth periodontal using machine‐driven hand instruments an adjunctive systemic antibiotics (500 mg 500 metronidazole three times day for 7 days). Clinical parameters were collected...
To report the 36-month follow-up of a trial comparing adjunct xenogenic collagen matrix (CMX) or connective tissue graft (CTG) to coronally advanced flaps (CAF) for coverage multiple adjacent recessions.125 subjects (61 CMX) with 307 recessions in 8 centres from parent were followed-up 36 months. Primary outcome was change position gingival margin. Multilevel analysis used centre, subject and tooth as levels baseline parameters covariates.No differences observed between randomized...
To determine the incidence of tooth loss in patients with generalized aggressive periodontitis (GAgP) during supportive periodontal therapy (SPT), identify risk factors, and quantify alveolar crest height changes on periapical X-ray follow-up.This retrospective study included 25 GAgP 656 teeth after treatment (baseline). Data were gathered sociodemographic, periodontal, radiological variables at baseline end follow-up. Linear regression models used to assess association factors...
Abstract Aim: To determine if the adjunctive use of intra‐muscular neridronate (NE) during non‐surgical periodontal treatment (PT) provides, in patients with generalized chronic periodontitis (GCP), benefits as compared PT alone 3 months after completion a 3‐month NE therapy. Material and Methods: Sixty GCP healthy were randomly assigned to control (CG) or test group (TG). CG received only. Thirty subjects TG also (12.5 mg an i.m. injection/week for months). Clinical parameters evaluated at...
Abstract Aim To evaluate the efficacy of different screening protocols for undiagnosed hyperglycaemia in a Research Network Dental Clinics coordinated by Spanish Society Periodontology (SEPA). Material and Methods A total 1143 patients were included study. Participants filled questionnaire considering diabetes risk factors (FINDRISC) received periodontal examination. Patients with slightly elevated score according to Findrisc (≥7), point‐of‐care HbA1c eventually referred their physician...
To evaluate the potential mid-term benefit of use a bone substitute material in reconstructive surgical treatment peri-implantitis.
To systematically assess the literature and report on (1) frequency of occurrence buccal soft tissue dehiscence (BSTD) at implants, (2) factors associated with BSTD (3) treatment outcomes reconstructive therapy for coverage BSTD.Two systematic reviews addressing focused questions related to implant occurrence, served as basis group discussions consensus statements. The main findings reviews, statements implications clinical practice future research were formulated within 3 further discussed...
To study the expression and role in vigabatrin (VGB)-induced gingival enlargement of Ki-67 antigen p27KIP1, p21WAF1, p53, proteins that activate or inhibit cell-cycle progression.Six patients treated with VGB for partial epileptic seizures refractory to classic anticonvulsant treatment were studied. Gingival biopsies taken from four these immunohistochemical studies; 10 control individuals healthy gingiva periodontal disease also evaluated.Four six presented some degree (mild moderate)....
No information is available on the perception of quality care in patients treated for periodontitis. The purpose this article was to assess how periodontitis-affected perceive periodontal treatment (PT) and measure factors which may influence it.
To evaluate radiographic bone level (RxBL) at dental implants and its associated factors in Spain.This cross-sectional study was performed by a network of sentinel dentists from regions Spain. RxBL defined as the distance implant shoulder to first clearly visible contact between surface bone. Radiographic measurements were two trained experienced periodontists. Implant patient data also collected. Descriptive, bivariate, discriminative multivariate analyses done.A total 49 provided 275...