Alfonso Martı́n
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiovascular Syncope and Autonomic Disorders
- COVID-19 and healthcare impacts
- COVID-19 Clinical Research Studies
- Cardiac electrophysiology and arrhythmias
- Venous Thromboembolism Diagnosis and Management
- Long-Term Effects of COVID-19
- Acute Myocardial Infarction Research
- Heart Failure Treatment and Management
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac pacing and defibrillation studies
- Acute Ischemic Stroke Management
- Gastrointestinal disorders and treatments
- Emergency and Acute Care Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Heart Rate Variability and Autonomic Control
- Cardiac Valve Diseases and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Palliative Care and End-of-Life Issues
- Advanced Radiotherapy Techniques
- Inflammatory Bowel Disease
- Takotsubo Cardiomyopathy and Associated Phenomena
- Cardiac Imaging and Diagnostics
- Prostate Cancer Treatment and Research
Hospital Universitario de Móstoles
2020-2024
Hospital Universitario Severo Ochoa
2014-2024
Sociedad Española de Cardiología
2005-2024
Sociedad Española de Medicina Interna
2003-2024
Hospices Civils de Lyon
2024
Impact
2023
Cohort (United Kingdom)
2023
Medical College of Wisconsin
2016-2022
Hospital Universitario Insular de Gran Canaria
2021
Hospital Clínico San Carlos
2001-2021
Abstract Aims We investigated the incidence, risk factors, clinical characteristics, and outcomes of pulmonary embolism (PE) in patients with COVID-19 attending emergency departments (EDs), before hospitalization. Methods Results retrospectively reviewed all diagnosed PE 62 Spanish EDs (20% EDs, case group) during first outbreak. without non-COVID-19 were included as control groups. Adjusted comparisons for baseline acute episode made between cases randomly selected controls (1:1 ratio)....
Intravenous procainamide and amiodarone are drugs of choice for well-tolerated ventricular tachycardia. However, the between them, even according to Guidelines, is unclear. We performed a multicentre randomized open-labelled study determine safety efficacy intravenous acute treatment tolerated wide QRS complex (probably ventricular) Patients were randomly assigned receive (10 mg/kg/20 min) or (5 min). The primary endpoint was incidence major predefined cardiac adverse events within 40 min...
We diagnosed 11 Guillain–Barré syndrome (GBS) cases among 71,904 COVID patients attended at 61 Spanish emergency departments (EDs) during the 2‐month pandemic peak. The relative frequency of GBS ED was higher in (0.15‰) than non‐COVID (0.02‰) (odds ratio [OR] = 6.30, 95% confidence interval [CI] 3.18–12.5), as standardized incidence (9.44 and 0.69 cases/100,000 inhabitant‐years, respectively, OR 13.5, CI 9.87–18.4). Regarding clinical characteristics, olfactory–gustatory disorders were more...
Recent reports of patients with coronavirus disease 2019 (COVID-19) developing pneumothorax correspond mainly to case describing mechanically ventilated patients. The real incidence, clinical characteristics, and outcome spontaneous (SP) as a form COVID-19 presentation remain be defined.Do the risk factors, outcomes SP in attending EDs differ compared without non-COVID-19 SP?This case-control study retrospectively reviewed all diagnosed (case group) 61 Spanish (20% EDs) them two control...
AimsTo assess the clinical presentation and acute management of patients with transient loss consciousness (T-LOC) in emergency department (ED).
Abstract Despite SARS-CoV-19 infection has a stereotypical clinical picture, isolated cases with unusual manifestations have been reported, some of them being well-known to be triggered by viral infections. However, the real frequency in COVID-19 is unknown. Analysing data 63 822 COVID patients attending 50 Spanish emergency department (ED) during outbreak, before hospitalisation, we report frequencies (myo)pericarditis (0.71‰), meningoencephalitis (0.25‰), Guillain–Barré syndrome (0.13‰),...
To determine the frequency and meaning of fluid inside intussusception at ultrasound (US) its relationship to irreducibility ischemia.US enabled diagnosis in 145 cases. Shape axial diameters area were determined. US-guided hydrostatic reduction was attempted 144 cases.Fluid present 20 cases (14%) appeared on images as an anechoic crescent between both serosal layers enfolded everted intussusceptum. No cystic structural anomaly detected surgery. Rates 89% (111 125) without 26% (five 19) with...
The COVID-19 pandemic has resulted in complete saturation of healthcare capacities, making it necessary to reorganise systems. In this context, we must guarantee the provision acute stroke care and optimise code protocols reduce risk SARS-CoV-2 infection rationalise use hospital resources. Madrid Stroke multidisciplinary group presents a series recommendations achieve these goals. We conducted non-systematic literature search using keywords "stroke" "COVID-19" or "coronavirus" "SARS-CoV-2."...
OBJECTIVES: Genome-wide association studies have reported the role of interleukin (IL)2-IL21chromosomal region at 4q27 in several autoimmune conditions. Mice deficient IL-2 develop a disease with clinical and histological similarity to ulcerative colitis (UC) humans. Modest evidence linkage UC was tentatively proposed for theIL2gene more than decade ago. Therefore, we decide investigate polymorphisms axis (IL2,IL2RA,andIL2RBgenes) inflammatory bowel diseases (IBDs). METHODS: Seven hundred...
The pregnane X receptor gene (PXR/NR1I2) has been recently associated with an increased risk for inflammatory bowel disease (IBD), although a subsequent case-control study failed to replicate the original association in independent population. This nuclear regulates genes involved detoxification process liver and intestine, like ABCB1/MDR1. PXR expression was significantly reduced colon of patients ulcerative colitis (UC), but remained unaffected Crohn's (CD) patients. Considering previous...
Objective To determine whether major histocompatibility complex class I chain–related gene A (MICA) polymorphisms are associated with susceptibility to rheumatoid arthritis (RA) independently of the HLA–DRB1 shared epitope (SE). Methods Fifty-four Spanish families an affected son or daughter and 211 consecutive RA patients were genotyped for HLA–DRB1, tumor necrosis factor a/b microsatellite alleles, MICA transmembrane polymorphism. We performed a case–control comparison independent...