László Sághy

ORCID: 0000-0003-2917-0583
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About
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Research Areas
  • Cardiac Arrhythmias and Treatments
  • Cardiac pacing and defibrillation studies
  • Atrial Fibrillation Management and Outcomes
  • Cardiac electrophysiology and arrhythmias
  • Cardiovascular Function and Risk Factors
  • Cardiovascular Syncope and Autonomic Disorders
  • Viral Infections and Immunology Research
  • Infective Endocarditis Diagnosis and Management
  • Cardiac Imaging and Diagnostics
  • Ion channel regulation and function
  • Congenital Heart Disease Studies
  • Cardiac Structural Anomalies and Repair
  • Cardiomyopathy and Myosin Studies
  • Cardiac Valve Diseases and Treatments
  • Cardiac tumors and thrombi
  • Neuroscience and Neural Engineering
  • Venous Thromboembolism Diagnosis and Management
  • Central Venous Catheters and Hemodialysis
  • Advanced X-ray and CT Imaging
  • Heart Rate Variability and Autonomic Control
  • Pain Management and Treatment
  • Infrared Thermography in Medicine
  • Vascular anomalies and interventions
  • Muscle Physiology and Disorders
  • Ultrasound in Clinical Applications

University of Szeged
2016-2025

Semmelweis University
2021

University Hospital Frankfurt
2020

Goethe University Frankfurt
2020

University of Debrecen
2019

University of Chicago
2013

Nagoya Heart Center
2013

Karolinska University Hospital
2013

Tokuda Hospital
2012

Hospital of the University of Pennsylvania
2011

Michele Brignole Andrés Moyá Frederik J. de Lange Jean‐Claude Deharo Perry Elliott and 95 more Alessandra Fanciulli Artur Fedorowski Raffaello Furlan Rose Anne Kenny Alfonso Martı́n Vincent Probst Matthew J. Reed Ciara Rice Richard Sutton Andrea Ungar J. Gert van Dijk Adam Torbicki Javier Moreno Victor Aboyans Stefan Agewall Riccardo Asteggiano Jean‐Jacques Blanc Natan Bornstein Serge Bovéda Héctor Bueno Haran Burri António Coca Jean‐Philippe Collet Giorgio Costantino Ernesto Díaz‐Infante Victoria Delgado Faas Dolmans Oliver Gaemperli Jacek Gajek Gerhard Hindricks Josef Kautzner Juhani Knuuti Piotr Kułakowski Ekaterini Lambrinou Christophe Leclercq Philippe Mabo Carlos A. Morillo Massimo Piepoli Marco Roffi Win K. Shen Iain A. Simpson Martin Stockburger Peter Vanbrabant Stephan Windecker José Luis Zamorano Stephan Windecker Victor Aboyans Stefan Agewall Emanuele Barbato Héctor Bueno António Coca Jean‐Philippe Collet Ioan Mircea Coman Verónica Dean Victoria Delgado Donna Fitzsimons Oliver Gaemperli Gerhard Hindricks Bernard Iung Peter Jüni Hugo A. Katus Juhani Knuuti Patrizio Lancellotti Christophe Leclercq Theresa McDonagh Massimo Piepoli Piotr Ponikowski Dimitrios Richter Marco Roffi Е. V. Shlyakhto Miguel Sousa‐Uva Iain A. Simpson José Luis Zamorano Franz Xaver Roithinger Alexandr Chasnoits Yves Vandekerckhove Vasil B Traykov Davor Puljević Elias Papasavvas Josef Kautzner Henning Mølgaard Mostafa Nawar Hannu Parikka Marija Vavlukis Olivier Piot Kakhaber Etsadashvili Thomas Klingenheben Spyridon Deftereos László Sághy Kristján Guðmundsson Roy Beinart Antonio Raviele Ayan Abdrakhmanov Erkin М Мirrakhimov Oskars Kalējs

10.1093/eurheartj/ehy037 article EN European Heart Journal 2018-03-19

The number of cardiac implantable electronic device (CIED) implantations has increased over recent years. Transvenous lead extraction (TLE), as a part an overall management strategy, also been increasing, not only consequence this growth, but because increasing rates infection, failure, awareness indications for management, and development tools. Clinical research is essential understanding efficacy risks TLE.

10.1093/europace/euy050 article EN EP Europace 2018-03-16

Pacemakers, implantable cardiac defibrillators, and resynchronization therapy devices are potentially life-saving treatments for a number of conditions, but not without risk. Most concerning is the risk electronic device (CIED) infection, which associated with significant morbidity, increased hospitalizations, reduced survival, healthcare costs. Recommended preventive strategies such as administration intravenous antibiotics before implantation well recognized. Uncertainties have remained...

10.1093/europace/euz246 article EN cc-by-nc EP Europace 2019-08-20

Abstract Pacemakers, implantable cardiac defibrillators, and resynchronization therapy devices are potentially life-saving treatments for a number of conditions, but not without risk. Most concerning is the risk electronic device (CIED) infection, which associated with significant morbidity, increased hospitalizations, reduced survival, healthcare costs. Recommended preventive strategies such as administration intravenous antibiotics before implantation well recognized. Uncertainties have...

10.1093/ejcts/ezz296 article EN European Journal of Cardio-Thoracic Surgery 2019-10-12

Abstract Pacemakers, implantable cardiac defibrillators, and resynchronization therapy devices are potentially lifesaving treatments for a number of conditions but not without risk. Most concerning is the risk electronic device (CIED) infection, which associated with significant morbidity, increased hospitalizations, reduced survival, health care costs. Recommended preventive strategies such as administration intravenous antibiotics before implantation well-recognized. Uncertainties have...

10.1093/eurheartj/ehaa010 article EN European Heart Journal 2020-01-10

Routine ultrasound (US) guidance for femoral venous access to decrease vascular complications of atrial fibrillation (AF) ablation procedures has been advocated. However, the benefit not unequivocally demonstrated by randomized-trial data.Consecutive patients undergoing pulmonary vein isolation (PVI) on uninterrupted anticoagulant treatment were included. A quasi-random allocation either US-guided or conventional puncture group was based which two procedure rooms patient scheduled in, with...

10.1111/jce.15893 article EN cc-by Journal of Cardiovascular Electrophysiology 2023-03-21

Cardiac implantable electronic device (CIED) infection rates are increasing. Worldwide compliance and disparities to published guidelines for the prevention, diagnosis management of these conditions not well elucidated. The purpose this survey, therefore, was clarify issues through an inquiry arrhythmia-related associations societies worldwide.A questionnaire comprising 15 questions related CIED infections distributed among members seven arrhythmia worldwide. A total 234 centres in 62...

10.1093/europace/euz137 article EN EP Europace 2019-04-18

Three-dimensional (3D) speckle tracking echocardiography (3DSTE) is a novel imaging modality for assessing cardiac function. We aimed to analyze left atrial (LA) function using 3DSTE in patients with fibrillation (AF).3DSTE was performed 20 prior their pulmonary vein isolation AF. Every patient underwent complete two-dimensional echocardiographic study at the same time. 3DSTE-derived circumferential (CS), longitudinal (LS), radial (RS), 3D (3DS), and area strain (AS) values were measured...

10.1111/echo.12218 article EN Echocardiography 2013-05-10

Egyre több vizsgálat eredménye utal a Purkinje-hálózat és Purkinje-myocardium-junctio szerepére malignus kamrai arrhythmiák kiváltásában. A bal distalis arborizációjának rádiófrekvenciás katéterablatiója befolyásolhatja kamrafibrilláció ismétlődését. Három beteg (mind férfi, életkor: 52 ± 6,6 év) esetében került sor amiodaron ellenére gyakran visszatérő miatt ablatiójára. Egyikük hypertrophiás, egy másik ischaemiás cardiomyopathiában szenvedett, harmadik idiopathiás volt diagnózis. célpont...

10.1556/650.2025.33209 article HU cc-by Orvosi Hetilap 2025-02-23

Abstract Background Better outcome has been suggested for repeat procedures after atrial fibrillation (AF) ablation, when recurrence presented as organized tachycardia (OAT) compared to recurrent AF. However, this contradicts the finding of more advanced remodeling in patients with OAT and may be related iatrogenesis by substrate modification during index procedure. Therefore, we examined prognostic significance type arrhythmia pulmonary vein isolation (PVI) without additional modification....

10.1002/joa3.70049 article EN cc-by-nc Journal of Arrhythmia 2025-03-25

Abstract Introduction Restoration and maintenance of sinus rhythm (SR) in the months before pulmonary vein isolation (PVI) by antiarrhythmic drug (AAD) therapy may lead to a better outcome persistent atrial fibrillation (AF). Amiodarone is only AAD that has been shown be effective not achieving control, but also reversing remodeling. It unknown, however if AF patients who convert upon amiodarone loading exhibit outcomes after ablation, compared those need electrical cardioversion (ECV)...

10.1093/europace/euaf085.403 article EN cc-by-nc EP Europace 2025-05-01

Abstract Background Implantable cardioverter defibrillator (ICD) systems are available in both single-chamber (SC) and dual-chamber (DC) configurations, with discrimination functions varying accordingly. Although expert opinion generally suggests that modern SC discriminators equipped morphology detection algorithms equally effective to DC tachyarrhythmia discrimination, only limited contradictory data available. In most previous reports the choice between or was determined by number of...

10.1093/europace/euaf085.583 article EN cc-by-nc EP Europace 2025-05-01

Abstract Introduction During the last decade, pulmonary vein isolation (PVI) has become most effective treatment for patients with atrial fibrillation. However, success rates after first interventions were less favourable, creating durable PV proved to be a technological challenge, consequently, repeated (redo) often performed. Purpose Our objective was examine how proportions of redo PVIs and reconnection rate have evolved in practice our institution light techological evolution past...

10.1093/europace/euaf085.450 article EN cc-by-nc EP Europace 2025-05-01

Atrial fibrillation (AF) is the most common cardiac arrhythmia and associated with an increased risk for stroke, heart failure cardiovascular-related mortality. Candidate targets anti-AF drugs include a potassium channel K(v)1.5, ionic currents I(KACh) late I(Na), along oxidative stress activation of NFAT-mediated gene transcription. As pharmacological management AF currently suboptimal, we have designed characterized multifunctional small molecule, compound 1 (C1), to target these ion...

10.1111/bph.12409 article EN British Journal of Pharmacology 2013-10-08

Randomized Trial of ICE During CTI Ablation. Introduction: Despite a high success rate, radio‐frequency ablation (RFA) the cavotricuspid isthmus (CTI) can be unusually challenging in some cases. We postulated that visualization with intracardiac echocardiography (ICE) could maximize succes decrease procedure and time, minimize radiation exposure. Methods Results: In our prospective, randomized study, we included 102 patients scheduled for ablation. 2 groups: guided only by fluoroscopy (n =...

10.1111/j.1540-8167.2012.02331.x article EN Journal of Cardiovascular Electrophysiology 2012-07-19

Termination of Persistent AF During Mapping. Complex fractionated atrial electrograms (CFAEs) may represent critical areas for the maintenance fibrillation (AF). While organization and termination have been reported with CFAE ablation, no reports arrhythmia during left mapping exist. We report a case reproducible catheter pressure at site remote from AF. (J Cardiovasc Electrophysiol, Vol. 22, pp. 1171-1173, October 2011)

10.1111/j.1540-8167.2011.02079.x article EN Journal of Cardiovascular Electrophysiology 2011-05-03
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